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Profiling of cholinesterase inhibitory and antioxidant activities of Artemisia absinthium, A. herba-alba, A. fragrans, Marrubium vulgare, M. astranicum, Origanum vulgare subsp glandulossum and essential oil analysis of two Artemisia species

dc.contributor.authorOrhan, I. Erdogan
dc.contributor.authorBELHATTAB, R.
dc.contributor.authorSenol, F. S.
dc.contributor.authorGulpinar, A. R.
dc.contributor.authorHosbas, S.
dc.contributor.authorKartal, MURAT
dc.contributor.institutionauthorKARTAL, MURAT
dc.date.accessioned2020-10-29T23:14:47Z
dc.date.available2020-10-29T23:14:47Z
dc.date.issued2010-11-01T00:00:00Z
dc.description.abstractIn the current study, cholinesterase inhibitory and antioxidant activities of the acetone and ethanol extracts of Artemisia absinthium, A. herba-alba, A. fragrans, Marrubium vulgare, M. astranicum, and Origanum vulgare var. glandulossum along with the essential oil of A. absinthium were investigated. Cholinesterase inhibitory activity was determined against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) at 25, 50, and 100 mu g/mL using an ELISA microplate reader. Antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity, ferrous ion-chelating ability, and ferric-reducing antioxidant power (FRAP) tests at 250, 500, and 1000 mu g/mL. Among the extracts, the highest inhibition against AChE (76.30 +/- 0.18% at 100 mu g/mL) and BChE (83.51 +/- 1.27% at 50 mu g/mL) was caused by the acetone extract of M. vulgare. The acetone extract of O. vulgare var. glandulossum showed a greater FRAP than that of the reference (chlorogenic acid). Essential oil compositions of A. absinthium and A. herba-alba were also analyzed by GC-MS. (C) 2010 Elsevier B.V. All rights reserved.
dc.identifier.citationOrhan I. E. , BELHATTAB R., Senol F. S. , Gulpinar A. R. , Hosbas S., Kartal M., -Profiling of cholinesterase inhibitory and antioxidant activities of Artemisia absinthium, A. herba-alba, A. fragrans, Marrubium vulgare, M. astranicum, Origanum vulgare subsp glandulossum and essential oil analysis of two Artemisia species-, INDUSTRIAL CROPS AND PRODUCTS, cilt.32, ss.566-571, 2010
dc.identifier.doi10.1016/j.indcrop.2010.07.005
dc.identifier.scopus77957227342
dc.identifier.urihttp://hdl.handle.net/20.500.12645/26962
dc.identifier.wosWOS:000283962300059
dc.titleProfiling of cholinesterase inhibitory and antioxidant activities of Artemisia absinthium, A. herba-alba, A. fragrans, Marrubium vulgare, M. astranicum, Origanum vulgare subsp glandulossum and essential oil analysis of two Artemisia species
dc.typeArticle
dspace.entity.typePublication
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local.publication.isinternational1
relation.isAuthorOfPublicationb30ec030-5f34-4c8b-814e-a7131d524a0a
relation.isAuthorOfPublication.latestForDiscoveryb30ec030-5f34-4c8b-814e-a7131d524a0a
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