Publication:
Effects of Laser and Ozone Therapies on Bone Healing in the Calvarial Defects

dc.contributor.authorAYDIN, MEHMET
dc.contributor.authorKazancioglu, Hakki Oguz
dc.contributor.authorEzirganli, Seref
dc.date.accessioned2020-10-22T18:10:56Z
dc.date.available2020-10-22T18:10:56Z
dc.date.issued2013-11-01T00:00:00Z
dc.description.abstractThis study aims to analyze the effect of the low-level laser therapy (LLLT) and ozone therapy on the bone healing of critical size defect (CSD) in rat calvaria. A total of 30 Wistar male rats were used. A 5-mm-diameter trephine bur was used to create CSD on the right side of the parietal bone of each rat calvarium. Once the bone was excised, a synthetic biphasic calcium phosphate graft material was implanted to all the bone defect sites. The animals were randomly divided into 3 groups as follows: the control group (n = 10), which received no LLLT or ozone therapy; the LLLT group (n = 10), which received only LLLT (120 seconds, 3 times a week for 2 weeks); and the ozone therapy group (n = 10) (120 seconds, 3 times a week for 2 weeks). After 1 month, all the rats were killed, and the sections were examined to evaluate the presence of inflammatory infiltrate, connective tissue, and new bone formation areas. Histomorphometric analyses showed that in the LLLT and ozone groups, the new bone areas were significantly higher than in the control group (P < 0.05). In the LLLT group, higher new bone areas were found than in the ozone group (P < 0.05). This study demonstrated that both ozone and laser therapies had a positive effect on bone formation in rat calvarial defect, compared with the control group; however, ozone therapy was more effective than LLLT (808 nm; 0.1 W; 4 J/cm(2); 0.028 cm(2), continuous wave mode).
dc.description.sponsorshipBezmiâlem Vakıf Üniversitesi
dc.identifier.citationKazancioglu H. O. , Ezirganli S., AYDIN M., -Effects of Laser and Ozone Therapies on Bone Healing in the Calvarial Defects-, JOURNAL OF CRANIOFACIAL SURGERY, cilt.24, ss.2141-2146, 2013
dc.identifier.doi10.1097/scs.0b013e3182a244ae
dc.identifier.pubmed24220424
dc.identifier.scopus84888350392
dc.identifier.urihttp://hdl.handle.net/20.500.12645/23999
dc.identifier.wosWOS:000330354500093
dc.titleEffects of Laser and Ozone Therapies on Bone Healing in the Calvarial Defects
dc.typeArticle
dspace.entity.typePublication
local.avesis.id77cfff5f-11fa-4eb7-87ac-ba363571de30
local.publication.isinternational1
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