Publication:
Heterologous booster COVID-19 vaccination elicited potent immune responses in HCWs

Simple item page
dc.contributor.authorSALTOĞLU, NEŞE
dc.contributor.authorDİNÇ, HARİKA ÖYKÜ
dc.contributor.authorBALKAN, İLKER İNANÇ
dc.contributor.authorCAN, GÜNAY
dc.contributor.authorOzbey, Dogukan
dc.contributor.authorBEYTUR, AYŞE NUR
dc.contributor.authorKESKİN, ELİF
dc.contributor.authorBUDAK, Beyhan
dc.contributor.authorAydogan, Okan
dc.contributor.authorMETE, BİLGÜL
dc.contributor.authorKARAALİ, RIDVAN
dc.contributor.authorERGİN, SEVGİ
dc.contributor.authorKOCAZEYBEK, BEKİR SAMİ
dc.contributor.institutionauthorDİNÇ, HARİKA ÖYKÜ
dc.date.accessioned2022-08-20T17:09:58Z
dc.date.available2022-08-20T17:09:58Z
dc.date.issued2022-10-01T00:00:00Z
dc.description.abstractThe objective of our study was to evaluate the antibody responses of health care workers (HCWs) who were vaccinated with booster dose BNT162b2 6 months after 2 doses of the CoronoVac vaccine. The study included 318 HCWs vaccinated with inactive CoronaVac SARS-CoV-2 vaccine in 2 doses. Anti-spike/RBD IgG levels were measured immediately before and 1 month after the booster dose. In the sixth month after Coro-naVac vaccination, the median of antibody levels of 1212.02 AU/ML, while it was 9283 AU/mL after BNT162b2 vaccination. IgG antibody titers of over 1050 AU/mL (which is equivalent to 1:80 dilution in the plaque reduction neutralization test) were detected in HCWs 15.09% and 97.8%, respectively. Our results showed that antibody titers increased 8-fold after the booster dose. We believe that the administration of the mRNA vaccine as a booster dose can provide more effective protection against COVID-19 infection, espe-cially in individuals with risk factors.
dc.identifier.citationSALTOĞLU N., DİNÇ H. Ö. , BALKAN İ. İ. , CAN G., Ozbey D., BEYTUR A. N. , KESKİN E., BUDAK B., Aydogan O., METE B., et al., -Heterologous booster COVID-19 vaccination elicited potent immune responses in HCWs-, DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, cilt.104, sa.2, 2022
dc.identifier.doi10.1016/j.diagmicrobio.2022.115758
dc.identifier.pubmed35878507
dc.identifier.urihttp://hdl.handle.net/20.500.12645/30880
dc.identifier.wosWOS:000834101500001
dc.titleHeterologous booster COVID-19 vaccination elicited potent immune responses in HCWs
dc.typeArticle
dspace.entity.typePublication
local.avesis.id66b3a228-d4df-489f-8316-335561799c7a
local.publication.goal03 - Sağlık ve Kaliteli Yaşam
local.publication.isinternational1
relation.isAuthorOfPublication6f44fd83-f5fa-4152-9576-c7c1d7ce6ad1
relation.isAuthorOfPublication.latestForDiscovery6f44fd83-f5fa-4152-9576-c7c1d7ce6ad1
relation.isGoalOfPublication9c198c48-b603-4e2f-8366-04edcfc1224c
relation.isGoalOfPublication.latestForDiscovery9c198c48-b603-4e2f-8366-04edcfc1224c
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Heterologous booster COVID-19 vaccination elicited potent immune responses in HCWs.pdf
Size:
321.09 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Yayınlar - Eserler