Publication:
Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, alpha-amylase, butyrylcholinesterase, and alpha-glycosidase enzymes

dc.contributor.authorBursal, Ercan
dc.contributor.authorAras, Abdulmelik
dc.contributor.authorKilic, Omer
dc.contributor.authorTaslimi, Parham
dc.contributor.authorGoren, AHMET CEYHAN
dc.contributor.authorGÜLÇİN, İlhami
dc.contributor.institutionauthorGÖREN, AHMET CEYHAN
dc.date.accessioned2019-10-05T21:08:00Z
dc.date.available2019-10-05T21:08:00Z
dc.date.issued2019-03-01
dc.description.abstractMany taxa of Salvia genus have been used in herbal beverages, food flavoring, cosmetics, and pharmaceutical industry. In this paper, chemical compounds of Salvia eriophora (S. eriophora) leaves were determined by LC-MS/MS (Liquid Chromatography tandem Mass Spectrometry). Salvigenin (158.64 +/- 10.8 mg/kg), fumaric acid (123.09 +/- 8.54 mg/kg), and quercetagetin-3.6-dimethylether (37.85 +/- 7.09 mg/kg) were detected as major compounds in the ethanol extract, whereas fumaric acid (555.96 +/- 38.56 mg/kg), caffeic acid (103.62 +/- 20.51 mg/kg), and epicatechin (83.19 +/- 8.43 mg/kg) were detected as major compounds in the water extract. Furthermore, enzyme inhibition of S. eriophora against acetylcholinesterase (AChE), alpha-amylase (AM), butyrylcholinesterase (BChE), and alpha-glycosidase (AG) enzymes were detected. AChE, BChE, AG, and AM enzymes were very strongly inhibited by S. eriophora water extract (WES) and S. eriophora methanol extract (MES). Additionally, antioxidant potential of S. eriophora was determined by in vitro analytical methods. IC50 values of WES and MES were performed for radicals.
dc.identifier10.1111/jdv.12556
dc.identifier.citationBursal E., Aras A., Kilic O., Taslimi P., Goren A. C. , GÜLÇİN İ., -Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, alpha-amylase, butyrylcholinesterase, and alpha-glycosidase enzymes-, JOURNAL OF FOOD BIOCHEMISTRY, cilt.43, 2019
dc.identifier.pubmed31353544
dc.identifier.urihttps://hdl.handle.net/20.500.12645/6569
dc.language.isoen
dc.titlePhytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, alpha-amylase, butyrylcholinesterase, and alpha-glycosidase enzymes
dc.typeArticle
dspace.entity.typePublication
local.article.journalnameJOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
local.avesis.ida3cb6b94-7748-4f66-9c3f-e744ac88fb59
local.avesis.response6445
relation.isAuthorOfPublication07fcea81-8515-4cd4-86f2-047fe6b2df71
relation.isAuthorOfPublication.latestForDiscovery07fcea81-8515-4cd4-86f2-047fe6b2df71
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