Person: BIYIK ÖZKAYA, DİLEK
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Publication Unilateral linear punctate palmar keratoderma(2014-05-01) Biyik Ozkaya, DİLEK; TAS, Betul; Su, Ozlem; UNAL CAKITER, Alkim; Tosuner, ZEYNEP; Demirkesen, Cuyan; Onsun, NAHİDE; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM; TOSUNER, ZEYNEP; ONSUN, NAHIDEPublication Demographic characteristics, aetiology, and assessment of treatment options in leukocytoclastic vasculitis.(2017-04-01) CAKıTER, AU; Kucuk, OS; OZKAYA, DB; TOPUKÇU, B; ONSUN, NAHİDE; SU KÜÇÜK, ÖZLEM; BIYIK ÖZKAYA, DİLEK; ONSUN, NAHIDEIntroduction: Vasculitides are a heterogeneous group of diseases characterized by inflammation of the blood vessel walls. Etiological factors include infections, drugs, connective tissue diseases, and malignancies. Aim: To examine the demographic characteristics, etiological factors, and treatment options in 75 patients with leukocytoclastic vasculitis. Material and methods: The study included 75 patients diagnosed with leukocytoclastic vasculitis at our clinic. The patients’ medical records were reviewed to determine their age, sex, presence of systemic symptoms, possible etiological factors, laboratory results, types of cutaneous lesions, locations of the lesions, treatment options, and disease course. Results: There were 43 women and 32 men. Cutaneous lesions affected only the lower limbs in 60 of the 75 patients (80%) and usually presented as palpable purpura (64%, n = 48). Arthralgia (26.7%, n = 20) was the most frequent extracutaneous symptom. Of the patients with secondary vasculitis, the most common causes were infections and drugs. The mean age of the patients with Henoch-Schönlein purpura was 26.8 years. There was no significant association between age and renal, gastrointestinal, or joint involvement. Conclusions: The most common form of vasculitis in our study was cutaneous leukocytoclastic vasculitis. In most of the patients it appeared to be idiopathic. Among drugs, antibiotics were the most common etiological factor. In 4 patients, the cutaneous leukocytoclastic vasculitis behaved like the paraneoplastic syndrome.Publication Poxvirus-induced angiogenesis after a thermal burn(2014-09-01) Biyik Ozkaya, DİLEK; TASKIN, Banu; TAS, Betul; ASIRAN SERDAR, Zehra; Demirkesen, Cuyan; Su, Ozlem; Onsun, NAHİDE; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDEOrf (contagious ecthyma) is a zoonotic infection caused by a dermatotropic parapoxvirus that commonly infects sheep, goats, and oxen. Parapoxviruses are transmitted to humans through contact with an infected animal or fomites. Orf virus infections can induce ulceration, and papulonodular, pustular, or ecthymic lesions of the skin after contact with an infected animal or contaminated fomite. Rarely, orf virus provokes extensive vasculo-endothelial proliferation as a skin manifestation. Here, we present the case of an 8-year old female with poxvirus-induced vascular angiogenesis that developed 10days after a thermal burn. An 8-year-old female presented at our outpatient clinic with red swellings and a yellow-brown crust on them. After a thermal burn with hot water, she went to a clinic and the burn was dressed with nitrofurazone and covered for 2days. When the dressing was removed after 2days, nodules were seen in the burnt areas. When the clinical findings were considered with the histopathological features, a reactive vascular proliferation due to a viral agent was suspected. Following PCR, parapoxvirus ovis was detected. Viral infections such as pox virus can trigger pyogenic granulomas or pyogenic granuloma-like vascular angiogenesis. Infectious agents must be considered when dealing with pyogenic granuloma-like lesions.Publication Localized Darier-s Disease(2016-08-01) BAHALI, Anil G.; Su, Ozlem; Biyik Ozkaya, DİLEK; Dizman, DİDEM; Yildiz, PELİN; Demirkesen, Cuyan; Onsun, NAHİDE; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; BIYIK ÖZKAYA, DİLEK; DİZMAN, DİDEM; YILDIZ, PELİN; ONSUN, NAHIDEPublication Role of Helicobacter pylori in Rosacea(2018-01-01T00:00:00Z) EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; BAHALI, ANIL GÜLSEL; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDEObjective: Rosacea is a chronic, inflammatory skin disease. The etiology is not known exactly, and natural immunity, impaired dermal matrix, vasodilation, and fibrogenesis may play a role in the pathogenesis of rosacea. Many studies investigated the relationship between rosacea and Helicobacter pylori (HP) but the results were contradictory. Methods: Patients were retrospectively identified from those treated by the Department of Dermatology. A total of 47 rosacea patients and 27 healthy controls were included in the study. Helicobacter pylori (Hp Ag), Helicobacter pylori immunoglobulin A (Hp IgA), and Helicobacter pylori immunoglobulin G (Hp IgG) were investigated and statistically compared in groups. Results: There was statistically no difference between the groups in terms of Hp Ag positivity (p=0.871), Hp IgA positivity (p=0.806), and Hp IgG positivity (p=0.330). Conclusions: Although we did not observe any difference between groups, we were unable to evaluate whether there is a reduction in symptoms with HP eradication. Further studies are needed to clarify the relation between HP infections with rosacea and other dermatological disorders.Publication Basosquamous Carcinoma Arising in a Leishmaniasis Scar(2017-09-17T00:00:00Z) EMİROĞLU, NAZAN; CENGİZ, FATMA PELİN; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDEPublication Pustulotic arthro-osteitis (sonozaki syndrome).(2011-03-01) Su, O; PIRMIT, S; OZKAYA, DB; KURAL, YB; ONSUN, NAHİDE; SU KÜÇÜK, ÖZLEM; BIYIK ÖZKAYA, DİLEK; ONSUN, NAHIDEPublication Borrelia burgdorferi Enfeksiyonu ve p83 Geni ile İlişkilendirilmiş Jeneralize Granüloma Anülare Moleküler Benzerlik Fenomeni ve Isı Şok Proteinleri ile Olası İlişkisi(2016-01-01) TAŞ, BETÜL; BIYIK ÖZKAYA, DİLEK; TAŞKIN, BANU; SAR, MEHMET; ÖZDEMİR, BİLGE; BIYIK ÖZKAYA, DİLEKPublication Extramammary paget disease: Case report Ekstramammaryan Paget Hastaliǧi(2016-12-30) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; SU, Özlem; Tosuner, ZEYNEP; BAHALI, ANIL GÜLSEL; YILDIZ, PELİN; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BIYIK ÖZKAYA, DİLEK; TOSUNER, ZEYNEP; SU KÜÇÜK, ÖZLEM; BAHALI, ANIL GÜLSEL; YILDIZ, PELİN; ONSUN, NAHIDEPublication Extramammary paget disease: Case report(2016-12-01) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; BIYIK ÖZKAYA, DİLEK; TOSUNER, ZEYNEP; BAHALI, ANIL GÜLSEL; YILDIZ, PELİN; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BIYIK ÖZKAYA, DİLEK; TOSUNER, ZEYNEP; SU KÜÇÜK, ÖZLEM; BAHALI, ANIL GÜLSEL; YILDIZ, PELİN; ONSUN, NAHIDE
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