Person: ALKAN, ALPAY
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Publication Open Access MRI and MR Spectroscopy Features of Heat Stroke: A Case Report(2018-07-01) Yilmaz, TEMEL FATİH; Aralasmak, AYŞE; Toprak, HÜSEYİN; GULER, Serhat; Tüzün, Umit; Alkan, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; ALKAN, ALPAYHeat stroke is the outcome of over heat stress that results in multiorgan dysfunction with a tendency for central nervous system damage. Brain is very sensitive to hyperthermia, especially the cerebellum that has selective vulnerability to heat stroke. There is complex interaction between heat cytotoxicity, coagulation disorder, cytotoxine - mediated systemic inflammatory response causing multiorgan failure, metabolic derangement, and circulatory insufficiency. We reviewed the literature and discussed brain MRI and MR spectroscopy findings of heat stroke, detailed the pathophysiology underlying brain involvement and proposed excitotoxic injury as an alternative mechanism of brain damage in heat stroke.Publication Metadata only Effects of contrast material on the metabolite ratios in single-voxel MR Spectroscopy of intraaxial brain tumors(2012-08-01) Alkan, ALPAY; Burulday, Veysel; Oztanir, Namik; Dogan, Metin; ERBAY, MEHMET FATİH; Kocak, Ayhan; Aralasmak, AYŞE; ALKAN, ALPAY; ÖZTANIR, MUSTAFA NAMIK; ARALAŞMAK, AYŞEAim: The purpose of our study was to determine whether the administration of contrast material affects the results of MR Spectroscopy (MRS) in different intraaxial brain tumors.Publication Open Access The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea(2014-01-01) KILICARSLAN, Rukiye; Alkan, ALPAY; Sharifov, RASUL; Akkoyunlu, MUHAMMED EMİN; Aralasmak, AYŞE; KOCER, Abdulkadir; KART, Levent; ALKAN, ALPAY; SHARIFOV, RASUL; AKKOYUNLU, MUHAMMED EMİN; ARALAŞMAK, AYŞEPurpose: We investigated diffusion alterations in specific regions of the brain in morbid obese, obese, and nonobese OSA patients and searched whether there is a correlation between BMI and ADC values. Materials and methods: DWIs of 65 patients with OSA were evaluated. The patients were classified according to BMI as morbid obese (n = 16), obese (n = 27), and nonobese (control, n = 22) groups. ADC measurements were performed from 24 different regions of the brain in each patient. The relationship of BMI with ADC values was searched. Results: The ADC values in hypothalamus, insular cortex, parietal cortex, caudate nucleus, frontal white matter, and posterior limb of internal capsule were all increased in obese patients (n = 43) compared to control group. The ADC values of midbrain, hypothalamus, orbitofrontal cortex, and parietal cortex were significantly increased in morbid obese compared to obese patients. In obese patients, the degree of BMI was positively correlated with ADC values of orbitofrontal cortex, parietal cortex, and hypothalamus. Conclusion: We observed increasing brain vasogenic edema with increasing BMI, suggesting that the main reason of brain diffusion alteration in patients with OSA could be obesity related.Publication Metadata only Evaluation of CSF flow metrics in patients with communicating hydrocephalus and idiopathic intracranial hypertension(2019-05-01) Yilmaz, TEMEL FATİH; Aralasmak, AYŞE; Toprak, HÜSEYİN; MEHDI, Elnur; KOCAMAN, Gulsen; Kurtcan, SERPİL; Kaya, MEHMET ONUR; Alkan, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; KURTCAN, SERPİL; KAYA, MEHMET ONUR; ALKAN, ALPAYPurpose To search for CSF dynamics of idiopathic intracranial hypertension (IIH) and communicating hydrocephalus and any correlation between MRI findings, CSF metrics and CSF opening pressure in IIH.Publication Metadata only MRI findings in thoracic outlet syndrome(2012-11-01) Aralasmak, AYŞE; ÇEVİKOL, CAN; KARAALİ, KAMİL; Senol, Utku; Sharifov, RASUL; KILICARSLAN, Rukiye; Alkan, ALPAY; ARALAŞMAK, AYŞE; SHARIFOV, RASUL; ALKAN, ALPAYWe discuss MRI findings in patients with thoracic outlet syndrome (TOS). A total of 100 neurovascular bundles were evaluated in the interscalene triangle (IS), costoclavicular (CC), and retropectoralis minor (RPM) spaces. To exclude neurogenic abnormality, MRIs of the cervical spine and brachial plexus (BPL) were obtained in neutral. To exclude compression on neurovascular bundles, sagittal T1W images were obtained vertical to the longitudinal axis of BPL from spinal cord to the medial part of the humerus, in abduction and neutral. To exclude vascular TOS, MR angiography (MRA) and venography (MRV) of the subclavian artery (SA) and vein (SV) in abduction were obtained. If there is compression on the vessels, MRA and MRV of the subclavian vessels were repeated in neutral. Seventy-one neurovascular bundles were found to be abnormal: 16 arterial-venous-neurogenic, 20 neurogenic, 1 arterial, 15 venous, 8 arterial-venous, 3 arterial-neurogenic, and 8 venous-neurogenic TOS. Overall, neurogenic TOS was noted in 69%, venous TOS in 66%, and arterial TOS in 39%. The neurovascular bundle was most commonly compressed in the CC, mostly secondary to position, and very rarely compressed in the RPM. The cause of TOS was congenital bone variations in 36%, congenital fibromuscular anomalies in 11%, and position in 53%. In 5%, there was unilateral brachial plexitis in addition to compression of the neurovascular bundle. Severe cervical spondylosis was noted in 14%, contributing to TOS symptoms. For evaluation of patients with TOS, visualization of the brachial plexus and cervical spine and dynamic evaluation of neurovascular bundles in the cervicothoracobrachial region are mandatory.Publication Metadata only CT Angiography Evaluation of Unusual Transorbital Penetrating Injury: A Toothbrush(2013-04-01) ATAY, Musa; Alkan, ALPAY; HANIMOGLU, Hakan; Sharifov, RASUL; KILICARSLAN, Rukiye; Aralasmak, AYŞE; ALKAN, ALPAY; SHARIFOV, RASUL; ARALAŞMAK, AYŞEOrbital penetrating injuries may cause significant harm to optic nerves and eyeball as well as to the brain and cerebral vasculature. Defining surrounding neurovascular structures by CT angiography (CTA) is important for surgical removal. We present an uncommon case of a 3-year-old child with a penetrating orbital injury caused by a toothbrush. To the best of our knowledge, there is no report orbital injury with a toothbrush so far.Publication Metadata only MRI findings in crural compartment syndrome: A case series(2014-01-01) YILMAZ, TEMEL FATİH; TOPRAK, HÜSEYİN; Bilsel, Kerem; ÖZDEMİR, HÜSEYİN; ARALAŞMAK, AYŞE; ALKAN, ALPAY; YILMAZ, TEMEL FATİH; TOPRAK, HÜSEYİN; BİLSEL, İSMAIL KEREM; ÖZDEMİR, HÜSEYIN; ARALAŞMAK, AYŞE; ALKAN, ALPAYPublication Metadata only Auditory Pathway Features Determined by DTI in Subjects with Unilateral Acoustic Neuroma(2016-12-01) KURTCAN, SERPİL; Alkan, ALPAY; Kilicarslan, R.; BAKAN, A. A.; TOPRAK, HÜSEYİN; ARALASMAK, AYŞE; AKSOY, FEYZA MÜBERRA; Kocer, A.; KURTCAN, SERPİL; ALKAN, ALPAY; TOPRAK, HÜSEYİN; ARALAŞMAK, AYŞEIn the studies concerning the pathology of the auditory pathway in the vestibulocochlear system, few use advanced neuroimaging applications of magnetic resonance imaging (MRI) such as diffusion tensor imaging (DTI). Those who did use reported DTI changes only at the lateral lemniscus and inferior colliculus level. The aim of our study was to determine diffusion changes in the bilateral auditory pathways of subjects with unilateral acoustic neuroma (AN) and compare them with healthy controls.Publication Metadata only Comparison of TOF MRA, Contrast-Enhanced MRA and Subtracted CTA from CTP inResidue Evaluation of Treated Intracranial Aneurysms(2017-11-10T00:00:00Z) DÜNDAR, TOLGA TURAN; SEYİTHANOĞLU, MEHMET HAKAN; ARALAŞMAK, AYŞE; Toprak, Huseyin; Kitiş, Serkan; Ozek, Erdinc; UYSAL, ÖMER; ALKAN, ALPAY; DÜNDAR, TOLGA TURAN; SEYİTHANOĞLU, MEHMET HAKAN; ARALAŞMAK, AYŞE; UYSAL, ÖMER; ALKAN, ALPAYPublication Metadata only Magnetic Resonance Spectroscopy Features of Heschl-s Gyri in Patients with Unilateral Acoustic Neuroma: Preliminary Study(2014-12-01) KILICARSLAN, Rukiye; Alkan, ALPAY; Aralasmak, AYŞE; AKSOY, Fadlullah; Toprak, HÜSEYİN; YETIS, Huseyin; Ozturan, ORHAN; ALKAN, ALPAY; ARALAŞMAK, AYŞE; AKSOY, FADLULLAH; ÖZTURAN, ORHANRationale and Objectives: To evaluate neurochemical alterations in Heschl-s gyri and determine the most affected side in case of Unilateral acoustic neuroma using magnetic resonance spectroscopy (MRS).