Person: KIRIK, FURKAN
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Publication Metadata only Diyabetik Retinopati ve Makulopati(2021-05-01T00:00:00Z) Özdemir, Mehmet Hakan; Kırık, Furkan; ÖZDEMİR, MEHMET HAKAN; KIRIK, FURKANOptik Koherens Tomografi (OKT), retinanın yüksek çözünürlükte görüntülenmesine olanak sağlayan, girişimsel olmayan bir görüntüleme yöntemidir. Retinal patolojiler hakkındaki kantitatif ve kalitatif verileri diğer görüntüleme yöntemlerinden daha hızlı elde etmeye olanak sağlaması nedeniyle diyabetik retinopatinin (DR) tanı ve takibinde OKT’den giderek daha fazla yararlanılmaktadır. OKT’nin oftalmolojik, özellikle de DR-de, kullanımıyla birlikte birçok retinal lezyon daha ayrıntılı tanımlanmaya başlandı ve hatta bazı retinal değişiklikler ilk defa OKT ile gösterildi. Daha önce yapılan araştırmalar sonucunda, DR’ye bağlı tespit edilen bir takım patolojik bulguların tedavi yanıtı üzerine ve nihai görme keskinliği üzerine öngörülebilir sonuçlar verdiği tespit edildi ve bu bulgulara prognostik değer biçilerek çeşitli biyobelirteçler tanımlandı. Günümüzde artık DR’ye ait çeşitli komplikasyonların tanısında sıklıkla faydalandığımız OKT görüntülerinin hastaya ait klinik bulgular ile birlikte değerlendirilmesi, hem uygulanacak tedavinin erkenden belirlenebilmesi hem de hastalık prognozunun öngörülebilmesi açısından faydalı olacaktır.Publication Metadata only Refractive precision in uncomplicated eyes with pseudoexfoliation: three-piece versus one-piece intraocular lens implantation(2021-01-01T00:00:00Z) Onur, Ismail Umut; Kirik, FURKAN; Yigit, Fadime Ulviye; Vural, Asli Deger; Cavusoglu, Ercan; Evcimen, Yusuf; KIRIK, FURKANPurpose: To evaluate the refractive precision of three-piece versus one-piece intraocular lenses (IOLs) in eyes with pseudoexfoliation (PXF) and changes in anterior chamber depth (ACD) following cataract surgery.Publication Metadata only Ophthalmological Perspective on Pediatric Ear, Nose, and Throat Infections(Springer, London/Berlin , 2021-11-01) Kırık F.; Özdemir M. H.; KIRIK, FURKAN; ÖZDEMİR, MEHMET HAKANThe majority of the tissues and organs that fall into the area of expertise of ear, nose and throat (ENT) specialists are adjacent to the orbit, and therefore to the globe. As a result of this contiguity, ENT diseases can spread to the orbit and present with various orbital complications. While these complications can be mild, they can also manifest as severe morbidities that lead to permanent loss of vision. In addition, ENT diseases can also spread to the cranium as well as the orbit, and lead to severe intracranial complications that may result in mortality. Such intracranial complications may also manifest with findings in an ophthalmological examination, as many cranial nerves (CNs) are also associated with the orbital structures. This is why ENT specialists commonly encounter ophthalmological findings as a result of both the orbital and cranial complications of infectious ENT diseases. In addition, ophthalmological examination findings are useful for diagnosis, as some infectious agents can cause a common infection both in the ocular and head-neck region.Publication Metadata only Acute Phototoxic Retinopathy due to Infrared Heater(2020-09-01T00:00:00Z) Kırık, Furkan; Çevik, Neslihan; Bayraktar, Havvanur; Özdemir, Mehmet Hakan; KIRIK, FURKAN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANPublication Metadata only Effects of 1,25 Dihydroxyvitamin D3 on Human Retinal Pigment Epithelial Cell Lines.(2021-05-22T00:00:00Z) Ekinci, Cansu; Guler, Eray Metin; Kocyigit, ABDÜRRAHİM; Ozdemir, Hakan; EKİNCİ, CANSU; KOÇYİĞİT, ABDÜRRAHİM; KIRIK, FURKANPublication Metadata only The relationship between preoperative anterior chamber parameters and postoperative refractive error in cataract surgery(2020-09-01T00:00:00Z) Koytak, İbrahim Arif; Kırık, Furkan; Özdemir, Mehmet Hakan; KIRIK, FURKAN; KOYTAK, İBRAHİM ARİF; ÖZDEMİR, MEHMET HAKANPurpose: Postoperative refraction has become important with improvements in cataract surgery. In this study, our aim was to investigate the effects of phacoemulsifi cation-intraocular lens (P-IOL) implantation on anterior chamber angle (ACA), anterior chamber volume (ACV), anterior chamber depth (ACD), and to assess relationship between these parameters and axial length (AL) and postoperative refractive error. Materials and Methods: We retrospectively reviewed data from 231 patients who underwent P-IOL implantation between January 2012 and June 2014. Scheimpfl ug imaging system was used for the determination of ACA, ACV and ACD values at preoperative and postoperative month 3. Partial coherence laser interferometry was used for preoperative AL, target postoperative refractive error and IOL power calculated by SRK-T formula. Spherical equivalent (SE=spherical error plus cylindrical error /2) at postoperative month 3 was recorded. Postoperative refractive error was calculated as mean error (ME=postoperative refraction-target refraction) and mean absolute error (MAE=absolute of ME). Data obtained at preoperative period and postoperative month 3 were compared. Results: Preoperative ACA, ACV, ACD were 30,2 ±12,1°, 130,7 ±41,2 mm³, 2,6 ±0,4 mm while postoperative ACA, ACV, ACD were 42,7 ±5,8°, 172,1 ±28,2 mm³, 4,1 ±0,7 mm respectively. Anterior chamber parameters were increased after P-IOL implantation, as all differences being statistically signifi cant (p=0.001). No signifi cant correlation was found between ME and ACA, ACV, ACD, AL. Again, no signifi cant correlation was found between MAE and ACA, ACV, ACD. Only a weak correlation was found between MAE and AL. Conclusion: Anterior chamber parameters measurements after P-IOL are signifi cantly increased compared to preoperative values. There was no signifi cant correlation between preoperative ACA, ACV, ACD and AL, and postoperative refractive error.Publication Metadata only Regional analysis of segmented-macular structure in patients with myopic anisometropia(2021-06-01T00:00:00Z) KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; Ozdemir, Hakan; KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANPurpose To compare intraretinal layers between the eyes in patients with myopic anisometropia, and evaluate the relationship between the layers with spherical equivalent (SE) and axial length (AL). Methods In this retrospective study, the more myopic (MM) and fellow (F) eyes of 41 patients with myopic anisometropia, and 38 emmetropic (+/- 0.50 diopter) control (C) eyes were inclueded. Intraretinal layer segmentation was performed by optical coherence tomography. Global volumes of retinal layers and their thicknesses in nine macular regions were compared. Correlation analysis was used to determine the relationship with SE and AL in each layer. Results Total retinal, ganglion cell (GCL), inner nuclear (INL), and outer plexiform (OPL) layer volumes in MM eyes were less than in C eyes, while INL and OPL were less than in F eyes. There was no difference in the fovea, except for the retinal pigment epithelium. In MM eyes, only INL and OPL were thin in at least one perifoveal and parafoveal quadrant compared to F eyes. Only INL and OPL thicknesses were significantly correlated with both SE and AL in all perifoveal quadrants. In contrast to the thinning found in MM eyes, the only layer in which thickening was detected to compare to C eye was nerve fiber layer (NFL), which correlated positively with SE and negatively with AL. Conclusion While the fovea is less affected by myopia, thinning becomes remarkable in the perifoveal quadrants. Despite thinning in many layers, especially INL and OPL, NFL thickening may be seen due to myopia.Publication Metadata only Cilioretinal artery occlusion and anterior ischaemic optic neuropathy due to periocular botulinum toxin a injection: A case report(2020-08-01T00:00:00Z) Kirik, Mehtap Ozkahraman; Arslan, Enver; KIRIK, FURKAN; KIRIK, FURKANPublication Open Access Evaluation of pediatric patients presenting with acute-onset unilateral transient acquired blepharoptosis(2022-01-01) KIRIK S.; KIRIK F.; YURTTUTAN N.; Gungor O.; Acipayam C.; KIRIK, FURKANPurpose: To evaluate the clinical features of pediatric patients with acute-onset, unilateral transient acquired blepharoptosis. Methods: In this retrospective study, the clinical records of patients between April 2015 and June 2020 were reviewed for evaluation of demographic features, accompanying neurological and ophthalmologic manifestations, symptom duration, etiological cause, and imaging findings. Patients with congenital and acquired blepharoptosis with chronic etiologies were excluded. Results: Sixteen pediatric patients (10 boys and 6 girls) with acquired acute-onset unilateral transient blepharoptosis were included in this study. The patients' mean age was 6.93 ± 3.16 years. The most commonly identified etiological cause was trauma in 7 patients (43.75%) and infection (para-infection) in 5 patients (31.25%). In addition, Miller Fisher syndrome, Horner syndrome secondary to neuroblastoma, acquired Brown's syndrome, and pseudotumor cerebri were identified as etiological causes in one patient each. Additional ocular findings accompanied blepharoptosis in 7 patients (58.33%). Blepharoptosis spontaneously resolved, without treatment, in all the patients, except those with Miller Fisher syndrome, neuroblastoma, and pseudotumor cerebri. None of the patients required surgical treatment and had ocular morbidities such as amblyopia. Conclusion: This study demonstrated that acute-onset unilateral transient blepharoptosis, which is rare in childhood, may regress without the need for surgical treatment in the pediatric population. However, serious pathologies that require treatment may present with blepharoptosis.Publication Metadata only Evaluation of dry eye and meibomian gland function in pregnancy(2023-01-01) Kunduracı M. S.; Koçkar A.; Helvacıoğlu Ç.; KIRIK F.; Karakuş Hacıoğlu G.; Akçay B. İ. S.; KIRIK, FURKANPurpose: To evaluate the signs and symptoms of dry eye in healthy pregnant women and investigate the effect of pregnancy on meibomian gland loss using non-contact meibography. Methods: Healthy pregnant women and age-matched healthy non-pregnant women were included in the study. Subjective symptoms were assessed using the Ocular Surface Disease Index (OSDI). The first and average non-invasive break-up times (first-NIBUT and avg-NIBUT, respectively) were determined, and the Schirmer test was applied. Non-contact meibography was performed. Results: The study included a total of 62 women, 30 pregnant (study group) and 32 non-pregnant (control group). There was no significant difference between the groups in terms of OSDI score and the Schirmer test (p > 0.05). The mean first-NIBUT and avg-NIBUT values of the study group (13.1 ± 5.3 and 13.7 ± 4.5 s) were significantly lower than the control group (16.0 ± 2.4 and 16.4 ± 1.5 s) (p: 0.015 and p: 0.040, respectively). The mean meibomian gland losses in the upper and lower eyelids were significantly higher in the study group (16.9 ± 8.2% and 11.6 ± 10.2%) compared to the control group (9.7 ± 6.2% and 5.6 ± 4.7%) (p < 0.001 and p: 0.011, respectively). Conclusions: It is considered that loss of the meibomian glands may occur during pregnancy, and this may predispose pregnant women to evaporative dry eye. Although dry eye does not cause significant ocular surface symptoms in pregnancy, NIBUT and non-contact meibography can be considered as effective diagnostic methods for the detection of dry eye in pregnant women.