Person: İZZETTİN, FIKRET VEHBI
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Publication Metadata only Determination of CYP2C19 polymorphisms, adverse drug reaction, and medication adherence in patients utilized selective serotonin reuptake inhibitors(2015-02-01T00:00:00Z) Deniz, Semanur; SANCAR, MESUT; OKUYAN, BETÜL; ATA, PINAR; Bingol-Ozakpinar, Ozlem; TALAS, Anil; GUNES, Tufan; CALISKAN, Mecit; Izzettin, Fikret Vehbi; İZZETTİN, FIKRET VEHBIPublication Metadata only Protective effect of ferulic acid on cisplatin induced nephrotoxicity in rats(2017-09-01T00:00:00Z) Bami, Erliasa; Ozakpinar, Ozlem Bingol; Ozdemir-Kumral, Zarife Nigar; Koroglu, Kutay; ERCAN, FERİHA; CIRAKLI, Zeynep; ŞEKERLER, TURGUT; Izzettin, FİKRET VEHBİ; SANCAR, MESUT; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBIThis study aims to determine the potential protective effects of ferulic acid against cisplatin-induced nephrotoxicity and to compare its effect with curcumin, a well-known protective agent against cisplatin- induced toxicity in rats. Administration of cisplatin resulted in high BUN (Blood Urea Nitrogen), creatinine, MDA (Malondialdehyde), MPO (Myeloperoxidase), TOS (Total Oxidative Status), PtNT (Protein Nitrotyrosine) levels (p < 0.05). Histological observations showed abnormal morphology of kidney; in addition with appearance of TUNEL positive cells indicating apoptosis in cisplatin administered group. HO-1 (Heme Oxygenase-1) levels measured by RT-PCR (Real Time Polymerase Chain Reaction), and TAS (Total Antioxidative Status) revealed antioxidant depletion due to cisplatin toxicity in animals (p < 0.05). All parameters showed improvement in groups treated with ferulic acid (p < 0.05). Ferulic acid treatment was found significant in preventing oxidative stress, increasing antioxidative status and regaining histological parameters to normal, indicating nephroprotective and antioxidant effects of this phenolic compound.Publication Metadata only Importance of medication dose adjustment in hospitalized patients with impaired renal function at internal medicine ward: the possible impact of clinical pharmacist(2018-02-01T00:00:00Z) Altan, Aysenur; Ozkan, Oznur; DEMIRTUNC, Refik; OKUYAN, BETÜL; Izzettin, Fikret Vehbi; SANCAR, MESUT; İZZETTİN, FIKRET VEHBIPublication Metadata only Evaluation of drug burden index and medication utilization in geriatric patients at community pharmacy(2015-02-01T00:00:00Z) SANCAR, MESUT; Girgin, Irem; Selcuk, Aysu; Yang, Seonkyeong; Izzettin, Fikret Vehbi; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBIPublication Metadata only Validation of the Turkish version of medication regimen complexity index among elderly patients(2016-10-01T00:00:00Z) OKUYAN, BETÜL; Babi, Bedis; SANCAR, MESUT; Ay, Pinar; YUCEL, Emre; YUCEL, Aylin; Izzettin, Fikret Vehbi; İZZETTİN, FIKRET VEHBIObjectiveThe aim of this study was to validate the Turkish version of the Medication Regimen Complexity Index- (MRCI).Publication Metadata only The assessment of self-medication utilization in pain management at a community pharmacy setting(2013-05-01T00:00:00Z) OKUYAN, BETÜL; Atalay, Mustafa Vakkas; Sahin, Ceren; Sahin, Duygucan; Izzettin, Fikret V.; SANCAR, MESUT; İZZETTİN, FIKRET VEHBIPublication Metadata only Tüberküloz tedavisi alan çocuk hastalarda yüksek basınçlı sıvı kromatografi yöntemi ile terapötik ilaç izlemi(2017-09-22) KARAKUŞ, SEVGİ; SANCAR, MESUT; DALGIC, NAZAN; OKUYAN, BETÜL; ÇAKIR, ERKAN; MIDYAT, LEVENT; ERENBERK, UFUK; İZZETTİN, FİKRET VEHBİ; ROLLAS, SEVİM; KAYMAKÇIOĞLU, BEDİA; ÇAKIR, ERKAN; ERENBERK, UFUK; İZZETTİN, FIKRET VEHBIPublication Metadata only Erratum to and corrections on the article entitled -Assessment of medication knowledge and adherence among patients under oral chronic medication treatment in community pharmacy settings-(2013-02-01T00:00:00Z) OKUYAN, BETÜL; SANCAR, MESUT; Izzettin, FİKRET VEHBİ; MORISKY, Donald E.; İZZETTİN, FIKRET VEHBIPublication Metadata only Opinion and knowledge towards pharmaceutical care of the pharmacists participated in clinical pharmacy and pharmaceutical care continuing education program Klinik eczaci{dotless}li{dotless}k ve farmasötik baki{dotless}m meslek i̇çi programi{dotless}na kati{dotless}lan eczaci{dotless}lari{dotless}n farmasötik baki{dotless}m hakki{dotless}ndaki bilgi düzeyleri ve görüşleri(2013-08-21T00:00:00Z) SANCAR, MESUT; OKUYAN, BETÜL; Apikoglu-Rabus, Sule; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBIPublication Metadata only Determination of side effects and medication adherence in major depression patients utilized antidepressants(2017-01-01T00:00:00Z) SANCAR, MESUT; Duzgun, Emine; OKUYAN, BETÜL; Deniz, Semanur; CALISKAN, Mecit; COSKUN, Kadir; Izzettin, Fikret Vehbi; İZZETTİN, FIKRET VEHBIThe aim of the study is to determine side effects, and medication adherence in patients who were diagnosed with major depression utilized antidepressants. This study was conducted in outpatient psychiatry clinic between February 2013 and May 2013. -Toronto Side Effects Scale- and 4-item Morisky-Green-Levine Medication Adherence Scale were evaluated. Fifty-six major depression patients (mean of age: 40.82 +/- 14.28 years old; male/female: 13/43) were included in this study. Patients were treated with escitalopram (46.4%), sertraline (26.8%), venlafaxine (10.7%), citalopram (8.9%) and paroxetine (7.1%). The most common side effects that patients reported were drowsiness/daytime somnolence (57.1%), dry mouth (46.4%) and increased sleep (46.4%), increased appetite (37.5%) and malaise or fatigue (30.4%). The most severity side effects that patients experienced were drowsiness/daytime somnolence (25%), increased sleep (19.6%) and decreased libido (14.3%). Only fifteen (26.8%) patients were found high adherent to their medication. It was concluded that although the frequency and severity of side effects have been found high, the percentage of patients- medication adherence has been obtained low. Patient education and monitoring regarding side effects and medication adherence providing by pharmacists would be contributed to prevent possible drug induced problems in these patients besides the routine services they are taken from outpatient clinic.
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