Person: ENHOŞ, ASIM
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Publication Predictive Role of Monocyte to High-density Lipoprotein Ratio for Plaque Morphology in Asymptomatic Intermediate Carotid Stenosis(2020-01-01T00:00:00Z) KARAÇÖP, ERDEM; ENHOŞ, ASİM; KARAÇÖP, ERDEM; ENHOŞ, ASIMPublication Heart sound recognition with deep neural networks(2018-10-24) MUTLUER, ahmet serdar; AKMAN, Alican; BACAKSIZ, AHMET; ÖZDEMİR, RAMAZAN; Enhoş, ASİM; AYDIN, TEOMAN; KESKİN, YAŞAR; UÇAR, Oğuzhan; BACAKSIZ, AHMET; ÖZDEMİR, RAMAZAN; ENHOŞ, ASIM; AYDIN, TEOMAN; KESKİN, YAŞARPublication Bulky calcification on the left coronary cuspis causing to critical stenosis of LMCA ostium after a succesful TAVI procedure(2017-10-08T00:00:00Z) BAKSHALİYEV, NİJAD; NASİFOV, MAHARRAM; ENHOŞ, ASİM; ÖZDEN TOK, ÖZGE; KARAÇÖP, ERDEM; ULUGANYAN, MAHMUT; HUYUT, MUSTAFA AHMET; BACAKSIZ, AHMET; ÇELİKKALE, İLKE; AKDEMİR, BARIŞ; GÖKTEKİN, ÖMER; ENHOŞ, ASIM; KARAÇÖP, ERDEM; ULUGANYAN, MAHMUT; BACAKSIZ, AHMET; ÇELİKKALE, İLKEPublication Homocysteine Levels in Patients with Heart Failure with Preserved Ejection Fraction(2010-01-01T00:00:00Z) Okuyan, Ertugrul; Uslu, Ahmet; Cakar, Mehmet Akif; Sahin, Irfan; Onur, Imran; Enhos, Asim; Biter, Halil Ibrahim; Cetin, Sukru; Dinckal, Mustafa Hakan; ENHOŞ, ASIMObjectives: Increased homocysteine (HCY) levels are associated with an increased risk of cardiovascular disease. Plasma HCY is increased in chronic heart failure (CHF) patients, and previous studies suggest that hyperhomocysteinemia causes adverse cardiac remodeling and affects pump function. We aimed to evaluate the HCY levels in patients with diastolic heart failure with preserved left ventricular ejection fraction (LVEF). Methods: We prospectively studied 68 patients (39 females and 29 males) who were hospitalized for symptomatic heart failure, as well as 40 age- and sex-matched healthy subjects who comprised the control group. CHF was diagnosed in all cases based on Framingham diagnostic criteria. CHF with preserved LVEF was defined as cases with CHF with an LVEF of 50% or more. Patients with regional left ventricular wall motion abnormalities, atrial fibrillation, and renal failure were excluded. Results: The mean age was 65.5 +/- 9.6 years in the heart failure group and 65.2 +/- 9.7 years in the control group. The mean LVEF was 59.8 +/- 5.3 in the heart failure group and 61.4 +/- 5.2 in the control group. The mean total fasting HCY concentrations were significantly higher in patients with heart failure (16.9 +/- 5.27 mu mol/l vs. 10.15 +/- 3.49 mu mol/l, respectively; p < 0.001). Multiple regression analysis indicated that NT-proBNP, hs-CRP, E/A ratio, and HbA1C were independently associated with hyperhomocysteinemia. Conclusions: Our results suggest that hyperhomocysteinemia is prevalent in heart failure with preserved ejection fraction. Larger scale studies are needed to clarify its pathogenic mechanisms and effects on the natural history of heart failure. Copyright (C) 2010 S. Karger AG, BaselPublication P Wave Duration/P Wave Voltage Ratio Plays a Promising Role in the Prediction of Atrial Fibrillation: A New Player in the Game(2021-05-01T00:00:00Z) KARAÇÖP, ERDEM; ENHOŞ, Asim; BAKHSALIYEV, NIJAD; ÖZDEMİR, Ramazan; KARAÇÖP, ERDEM; ENHOŞ, ASIM; BAKHSALIYEV, NIJAD; ÖZDEMİR, RAMAZANBackground. Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. Identification of patients at risk for developing AF and the opportunity for early targeted intervention might have a significant impact on morbidity and mortality. Prolonged P wave duration and decreased P wave voltage have been shown to be independent predictors of AF. The present study aimed to investigate the role of P wave duration/P wave voltage in predicting new-onset AF. Methods. We screened a total of 640 consecutive patients who admitted to cardiology outpatient clinic with a complaint of palpitation between 2012 and 2014. 24-h Holter monitoring, echocardiography, and electrocardiography (ECG) recordings were reviewed to identify new-onset AF. Patients were assigned into two groups based on presence (n = 150) and absence (n = 490) of new-onset AF. Previous ECGs with sinus rhythm were analyzed. P wave duration was measured in inferior leads, and P wave voltage was measured in lead one. P wave duration/P wave voltage was also calculated for each patient. Results. One hundred fifty subjects (23.4%) had new-onset AF among 640 patients. P wave duration (123.27 +/- 12.87 vs. 119.33 +/- 17.39 ms, p=0.024) and P wave duration/P wave voltage (1284.70 +/- 508.03 vs. 924.14 +/- 462.06 ms/mV, p<0.001) were higher, and P wave voltage (0.12 +/- 0.04 vs. 0.13 +/- 0.04 mV, p<0.001) was significantly lower in the new-onset AF group compared with non-AFs. P wave duration/P wave voltage, with a cut off of 854.5 ms/mV, had 83.3% sensitivity and 62.0% specificity in a receiver operating characteristic curve (AUC 0.728, 95% CI 0.687-0.769; p<0.001). Their negative and positive predictive values were 78.7% and 68.6%, respectively. In a univariate regression analysis, age, smoking, C-reactive protein, brain natriuretic peptide, left atrial diameter, left atrial volume index, P wave duration, P wave voltage, and P wave duration/P wave voltage were significantly associated with the development of new-onset AF. Moreover, smoking (OR 4.008, 95% CI 1.707-9.409; p=0.001), left atrial volume index (OR 7.108, 95% CI 4.400-11.483; p<0.001), and P wave duration/P wave voltage (OR 1.002, 95% CI 1.000-1.003; p=0.044) were found to be significant independent predictors of new-onset AF in a multivariate analysis, after adjusting for other risk parameters. Conclusion. The P wave duration/P wave voltage ratio is a practical, easy-to-use, cheap, and reliable electrocardiographic parameter, which can play a promising role for both in predicting and elucidating a mechanism of new-onset AF.Publication The relationships between blood pressure, blood glucose, and bone mineral density in postmenopausal Turkish women(2015-01-01T00:00:00Z) Cakmak, Huseyin Altug; Cakmak, Burcu Dincgez; Yumru, Ayse Ender; Aslan, Serkan; Enhos, Asim; Kalkan, Ali Kemal; İNCİ COŞKUN, EBRU; Acikgoz, Abdullah Serdar; Karatas, Suat; ENHOŞ, ASIMBackground: Hypertension, diabetes mellitus, and osteoporosis are important comorbidities commonly seen in postmenopausal women. The aim of the present study was to investigate the relationships between blood pressure, blood glucose, and bone mineral density (BMD) in postmenopausal Turkish women.Publication The analysis of the relationship between low vitamin D levels and cardiovascular diseases: hypertension, cardiac hypertrophy, atrial fibrillation, stroke(2020-12-06T00:00:00Z) UÇAR, OĞUZHAN; BACAKSIZ, AHMET; KULA, ASLI YAMAN; ÖZDEMİR, RAMAZAN; HOCAOĞLU, NİSA; ENHOŞ, ASİM; KARAÇÖP, ERDEM; BACAKSIZ, AHMET; ÖZDEMİR, RAMAZAN; ENHOŞ, ASIM; KARAÇÖP, ERDEMPublication Relation of coronary collateral circulation with epicardial fat volume in patients with stable coronary artery disease(2013-01-01T00:00:00Z) Enhos, Asim; Sahin, Irfan; Can, Mehmet Mustafa; Biter, Ibrahim; Dinckal, Mustafa Hakan; Serebruany, Victor; ENHOŞ, ASIMObjective To investigated the relationship between epicardial fat volume (EFV) and coronary collateral circulation (CCC) in patients with stable coronary artery disease (CAD). Methods The study population consisted of 152 consecutive patients with CAD who underwent coronary angiography and were found to have at least 95% significiant lesion in at least one major coronary artery. EFV was assessed utilizing 64-multislice computed tomography. The patients were classifield into impaired CCC group (Group 1, Rentrop grades 0-1, n = 58), or adequate CCC (Group 2, Rentrop grades 2-3, n = 94). Results The EFV values were significantly higher in paitients with adequate CCC than in those with impaired CCC. In multivariate logistic regression analysis, EFV (OR = 1.059; 95% CI: 1.035-1.085; P = 0.001); and presence of angina were independent predictors of adequate CCC. In receiver-operating characteristic curve analysis, the EFV value > 106.5 mL yielded an area under the curve value of 0.84, with the test sensitivity of 49.3%, and with 98.3% specifity. Conclusions High EFV, and the presence of angina independently predict adequate CCC in patients with stable coronary artery disease. This association offers new diagnostic opportinities to assess collateral flow by conventional ultrasound techniques.Publication Association Between Contrast Media Volume-Glomerular Filtration Rate Ratio and Contrast-Induced Acute Kidney Injury After Primary Percutaneous Coronary Intervention(2015-07-01T00:00:00Z) Celik, Omer; Ozturk, Derya; Akin, Fatih; Ayca, Burak; Yalcin, Ahmet Arif; Erturk, Mehmet; Biyik, Ismail; Ayaz, Ahmet; Akturk, Ibrahim Faruk; Enhos, Asim; Aslan, Serkan; ENHOŞ, ASIMWe hypothesized that contrast media volume-estimated glomerular filtration rate (CV-e-GFR) ratio may be a predictor of contrast media-induced acute kidney injury (CI-AKI). We investigated the associations between CV-e-GFR ratio and CI-AKI in 597 patients undergoing primary percutaneous coronary intervention (pPCI). An absolute 0.3 mg/dL increase in serum creatinine compared with baseline levels within 48 hours after the procedure was considered as CI-AKI; 78 (13.1%) of the 597 patients experienced CI-AKI. The amount of contrast during procedure was higher in the CI-AKI group than in those without CI-AKI (153 vs 135 mL, P = .003). The CV-e-GFR ratio was significantly higher in patients with CI-AKI than without (2.3 vs 1.5, P 2 (P < .001, OR = 5.917). In conclusion, CV-e-GFR ratio is significantly associated with CI-AKI after pPCI.Publication Tam kan sayımında belirlenen nötrofil/lenfosit oranı pulmoner tromboemboli hastalarında mortalite belirteci olarak kullanılabilir mi?(2020-10-01T00:00:00Z) TURNA, FAHRETTİN; ENHOŞ, ASİM; ENHOŞ, ASIM