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YILDIZ, KEMALETTİN

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KEMALETTİN
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YILDIZ
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Start date: 2020 × End date: 2023 × Type: Article ×

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Now showing 1 - 8 of 8
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    The Role of Staged Cryosurgery and Three-Dimensional Computed Tomography Integrated Navigation System in the Surgical Management of Severe Involvement of Craniofacial Polyostotic Fibrous Dysplasia
    (2020-01-01T00:00:00Z) Dündar, Tolga Turan; YILDIZ, KEMALETTİN; DÜNDAR, TOLGA TURAN; MEHDIZADE, TURAN; GÜNEREN, ETHEM
    Fibrous dysplasia (FD) is a developmental bone disorder caused by the hamartamatous proliferation of bone-forming cells. A 29-year-old male patient with diagnosis of FD was admitted to our clinic with the symptoms of severe craniomaxillofacial involvement of FD beginning from last year. Neurological examination revealed diplopia, horizontal nystagmus, conductive hearing loss, and partial vision loss. In his medical history, it was reported that he had undergone intramedullary nailing operation in his left femur due to a pathological fracture approximately 8 years ago in the orthopedics clinic of our institution. The patient underwent 3 consecutive surgeries by our plastic and neurosurgical team. The patient was followed-up in the neuro-intensive care unit between the surgical sessions and 1 week after the last operation. Afterwards, he was transferred to the neurosurgical department. No postoperative complication was detected. The preoperative signs were recovered. During his 6th month follow-up control-visit, all his preoperative symptoms were improved. In addition, the patient was satisfied with his postoperative cosmetic improvement. In conclusion, virtual surgical planning and intraoperative surgical navigation systems can make the challenging cases possible to operate with increasing
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    PublicationOpen Access
    Generation of Bone Tissue Using Adipose Tissue-derived Stem Cells
    (2021-07-01T00:00:00Z) Baygol, Emre Gonenc; GÜNEREN, Ethem; Karaaltin, Mehmet Veli; Canter, Halil Ibrahim; Ozturk, Kahraman; Ovali, Ercument; Ozpur, Mustafa Aykut; YILDIZ, KEMALETTİN; Eyuboglu, Fatma; GÜNEREN, ETHEM; YILDIZ, KEMALETTİN
    Objective: Bone grafts and even bone substitutes do not meet all of the requirements of bony reconstructions. The aim of this study was to generate bone tissue from autologous adipose tissue-derived mesenchymal stem cells (ATDMSCs) and decellularised bone allografts. Methods: A 1.5 cm bone defect developed in the middle third of the rabbit's ulna. Reconstructions were carried out using miniplate and screws and interpositional autogenous bone grafts according to the designs of the groups: (1) No touch, (2) cryopreserved, (3) decellularised and (4) ATDMSCs-implanted decellularised bones. Before implantation, ATDMSCs in the last group were labelled with Q-dot and identified microscopically. Results: Graft recovery and irregular callus formation were observed in the first, second and forth groups. In the first group, the organisation of Haversian systems, the structure of the lacunae and the presence of canaliculi ossiums were observed; in the second group, approximately 40% of the Haversian canals contained blood vessels, and canaliculi ossiums in the form of thin filaments were found in 90% of the microscopically examined areas; in the third group, most Haversian canals were empty, most osteocyte canals were devoid of cells, and canaliculi ossiums were absent; in the fourth group, some of the Haversian canals contained blood vessels, and there were partly lacunae containing cells due to decellularisation, whereas in approximately 50% of the examined microscope areas, the presence of canaliculi ossiums with evidence of mesenchymal stem cells differentiated into osteocytes was demonstrated by Q-dot traced cells. Conclusion: In this study, the establishment of a proper niche environment for adipose-derived mesenchymal cells promotes their development into osteogenic cells.
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    The benefit of replacing the excess costal cartilage in rhinoplasty
    (2022-03-01T00:00:00Z) ÖZTURAN, ORHAN; YENİGÜN, ALPER; YURTSEVER, İSMAİL; ÖZDEM, ABDULLAH; YILDIZ, KEMALETTİN; ÖZTURAN, ORHAN; YENİGÜN, ALPER; YURTSEVER, İSMAİL; ÖZDEM, ABDULLAH; YILDIZ, KEMALETTİN
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    A Distinct Technique of Intermaxillary Fixation Screw Application to Condylar Process to Fracture Reduction in Open Approach of Condylar Fracture Treatment
    (2021-11-01T00:00:00Z) YILDIZ, KEMALETTİN; YENİOCAK, ALİ; ERGÜN, SELMA; Canter, Halil Ibrahim; YILDIZ, KEMALETTİN; YENİOCAK, ALİ; ERGÜN, SELMA
    The aim of this letter is to present the surgical experience obtained from a patient, in whom the proximal segment was better manipulated for precise alignment after application of the intermaxillary fixation screw.
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    PublicationOpen Access
    Boneless Maxillary Reconstruction
    (2020-01-01T00:00:00Z) Kelahmetoğlu, Osman; Güneren, Ethem; Kuzu, Ismail Melih; Yıldız, Kemalettin; KELAHMETOĞLU, OSMAN; GÜNEREN, ETHEM; YILDIZ, KEMALETTİN
    Objective: Although the midface is supported by maxillary bone, reconstruction of maxillary bony defects does not always require osseous reconstruction. A series of maxillary facial defects of moderate to severe sizes (Brown and Shaw 4-6) uniformly reconstructed with myocutaneous free flaps is presented. Methods: Retrospective analysis was done for consecutive 10 cases between 2013-18. Seven of the cases had defects caused by oncological resection and 3 defects caused by trauma. Free vertically oriented rectus abdominis (fVRAM) flap was used to reconstruct these defects. The mean age of patients was 42.9 years (range=20-71 years). All flaps survived and 2 flaps had small skin island problems. Rapid recovery, low morbidity, acceptable oral competency, and satisfactory cosmetic appearance were obtained with the reconstruction using fVRAM flaps. Conclusion: According to our limited experience, acceptable reconstruction of extensive maxillary defects can be done with using only soft tissue flap, which is versatile and safe.
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    McFARLANE RAT DORSAL CİLT FLEP MODELİNDE AMNİOMAX’IN NEKROZ ÖNLEYİCİ ETKİSİNİN ARAŞTIRILMASI
    (2020-07-01T00:00:00Z) Dündar, Tolga Turan; Yıldız, Kemalettin; Tosuner, Zeynep; Mihrapoğlu, Semih Lütfi; Kitiş, Serkan; DÜNDAR, TOLGA TURAN; YILDIZ, KEMALETTİN; KİTİŞ, SERKAN
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    Hybrid reconstruction of distal nasal defects
    (2021-01-01T00:00:00Z) YILDIZ, KEMALETTİN; Gorgulu, Tahsin; Yesiloglu, Nebil; Kelahmetoglu, Osman; ÇAMLI, MEHMET FATİH; Canter, Halil Ibrahim; YILDIZ, KEMALETTİN; ÇAMLI, MEHMET FATİH
    We present hybrid reconstruction of distal lateral -through-and-through- nasal defects (skin, cartilage, and mucosa) due to resection of tumor and/or infection. Retrospective descriptive study. The study was performed in multicenter clinics between July 2011 and September 2016. 13 patients with full thickness distal nasal defects secondary to tumor and/or infection were included. Defects included dorsal and/or caudal septum, upper lateral cartilage, or inner/outer nasal valve. Caudal-based turn-in flaps were planned and used to repair inner lining of nasal cavity. Conchal and septal cartilages were used as cartilage grafts. Skin defects were reconstructed with lateral nasal artery perforator flaps. All flaps healed uneventfully, without flap loss. Nasal passage collapse, adhesion, or difficulty in breathing were not seen. No hematoma, infection, and deformity at cartilage graft donor areas was observed. During nasal reconstruction, it is mandatory to consider 3D complex and functional structure of nose. The repair of skin defects may not be enough for functional restoration. We believe that single step reconstruction of full thickness nasal defects through hybrid reconstruction may lead to anticipated successful results.
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    PublicationOpen Access
    The Effect of Vitamin D3 on Skeletal Muscle in Rat after Ischemia Reperfusion Injury: Preliminary Report
    (2020-07-01T00:00:00Z) Kelahmetoğlu, Osman; Tok, Enis Olgu; Özer, Ömer Faruk; Yeniocak, Ali; Yağmur, Çağlayan; Eşrefoğlu, Mukaddes; Koçyiğit, Abdürrahim; Yıldız, Kemalettin; Güneren, Ethem; KELAHMETOĞLU, OSMAN; ÖZER, ÖMER FARUK; YENİOCAK, ALİ; EŞREFOĞLU, MUKADDES; KOÇYİĞİT, ABDÜRRAHİM; YILDIZ, KEMALETTİN; GÜNEREN, ETHEM
    Objective: Vitamin D is a vitamin that has gained popularity in recent years and has an anti-inflammatory and immunmodular effect. In the literature review we conducted, there was no study investigating the effect of vitamin D to prevent ischemia reperfusion (I/R) injury in skeletal muscle. The aim of this study was to investigate the effect of vitamin D on skeletal muscle in I/R injury. Methods: Six rats were used in each group including ischemia group (group I) and experimental group (group D given vitamin D). In the histopathological examination, inflammation and apoptosis levels were studied in gastrocnemius muscle. In biochemical analysis, total oxidative stress and total antioxidant and catalase levels were evaluated in anterior tibialis muscle. Results: The number of apoptotic cells in group D were found significantly lower than group I. In the terms of total antioxidants and catalase levels, there were significant difference between group D and group I. Conclusion: Our results support the hypothesis that vitamin D is an agent that can be used to prevent I/R injury.