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BAKAR, RABIA ZEHRA

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RABIA ZEHRA

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BAKAR

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Now showing 1 - 10 of 13
  • Publication
    Excision of subcutaneous endometriosis lesions in obese patients by marking them with methylene blue with ultrasound guidance: a novel technique
    (2023-01-01) ÇETİN Ç.; KÜTÜK M. S.; Tanoğlu F. B.; ATEŞ S.; ÖZCAN P.; BAKAR R. Z.; ÇETİN, ÇAĞLAR; KÜTÜK, MEHMET SERDAR; TANOĞLU, FATMA BAŞAK; ATEŞ, SEDA; ÖZCAN, PINAR; BAKAR, RABIA ZEHRA
  • Publication
    Hidradenoma papilliferum of the paraurethral area: Case report Paraüretral Yerleşimli Hidradenoma Papilliferum
    (2016-05-13) BAKAR, RABİA ZEHRA; Sönmez, FATMA CAVİDE; Dane, Banu; BAKAR, RABIA ZEHRA; SÖNMEZ, FATMA CAVİDE; KILIÇOĞLU DANE, PAKİZER BANU
  • Publication
    Effect of maternal smoking during pregnancy on fetal circulation and growth
    (2023-06-25) Kütük M. S.; Bakar R. Z.; Toluk Ö.; Çetin Ç.; Yozgat C. Y.; Doygun Ö.; KÜTÜK, MEHMET SERDAR; BAKAR, RABIA ZEHRA; TOLUK, ÖZLEM; ÇETİN, ÇAĞLAR
    Objective To understand the pathogenic mechanism of smoking on abnormal fetal growth by assessing the umbilical, and middle cerebral pulsatility index (MCA- PI, and UmA-PI, respectively) cerebroplacental ratio (CPR) and middle MCA peak systolic velocity (MCA-Vmax). Methods A hundred and eighty-one pregnant women were included in the study, 118 of whom were ever smoker and 62 were smoker. Smoking status of the cases were based on the participants statements and confirmed with breath CO test. Patients were undergo Doppler examination according to thecurrent guidelines at 24, 28, 32 and 36 weeks and the results were expressed as z- scores. UmA- PI, MCA-PI, CPR (MCI-PI/UmA-PI), MCA- Vmax were compared between control and smoking groups. As a subgroup analysis, effect of heavy smoking (>10/day) on fetal growth and Doppler indexes were also compared. Results Body mass index (BMI), gravida, rate of gestational hypertension and neonatal intensive care admission is significantly higher in smoking group. Birthweight and gestational age at birth was significantly higher in control group [3355 (1960.0-4660.0) vs 3162.5(550.0-4190.0), p=0.003, and274.0(250.0-294.0) vs. 271(175.0-288.0), p=0.015, respectively]. When controlled for confounding factors, no significant difference was detectedbetween smokers and control groups with regard to UmA-PI, MCA-PI, MCA- V Max and CPR, at 24 , 28 , 32 , 36 weeks. EFW at all gestational ages were significantly lower in smoker group (p=0.033). At subgroup analysis, no significant difference was detected between control and heavy smokers in terms of EFW and all Doppler parameters. Conclusion Smoking during pregnancy is associated decreased fetal growth and increased abnormal neonatal outcome. However, it has no demonstrable effect on any of the Doppler indexes and velocities at any given gestational ages. Abnormal effect of smoking on fetal growth seems not to operate throughimpaired uteroplacental circulation
  • Publication
    Clinical predictors of successful vaginal myomectomy for prolapsed pedunculated uterine leiomyoma
    (2018-08-06) Aydın, SERDAR; Göksever, Çelik; MARASLI, MUSTAFA; BAKAR, RABİA ZEHRA; AYDIN, SERDAR; MARAŞLI, MUSTAFA; BAKAR, RABIA ZEHRA
    Objective: Uterine leiomyomas are the most common pelvic tumor in women. The calculated prevalence of prolapsed pedunculated leiomyoma was 2.5% in patients who underwent surgery. Although vaginal removal is safe and effective, hysterectomy demand is questionable. We aimed to analyze the association between patient characteristics, clinical features of prolapsed pedunculated submucosal leiomyoma, and the probability of successful vaginal myomectomy. Material and Methods: This study was conducted in 35 women who presented with prolapsed pedunculated uterine leiomyoma. Patients were grouped according to the treatment procedure, either vaginal myomectomy or hysterectomy. Results: Hysterectomy was performed in 14 patients and vaginal myomectomy was performed in 21 women. The mean ages and menopausal status were similar. Parity was higher in the hysterectomy group (p=0.02). The preoperative hematocrit value of patients undergoing vaginal myomectomy was significantly lower (p=0.04). There was no significant difference between the groups regarding the largest leiomyoma diameter. However, the median calculated leiomyoma volume was lower in the vaginal myomectomy group (p=0.04). None of the variables were independently associated with successful vaginal myomectomy on multivariable logistic regression analysis. Conclusion: The feasibility and choice of vaginal myomectomy is associated with low parity, absence of coexisting leiomyoma, high volume of leiomyoma estimated via ultrasound measurement, and severe anemia. (J Turk Ger Gynecol Assoc 2018; 19: 146-50) Keywords: Leiomyoma, prolapsed pedunculated submucosal leiomyoma, vaginal myomectomy, hysterectomy
  • Publication
    A case of HELLP syndrome complicated with acute pancreatitis Akut Pankreatit ile Komplike HELPP Sendromu
    (2016-05-13) BAKAR, RABİA ZEHRA; AYDIN, SERDAR; Aydin, SİNEM; ARIOGLU AYDIN, Çaǧri; BATMAZ, Gonca; BAKAR, RABIA ZEHRA; AYDIN, SERDAR; AYDIN, SİNEM
  • Publication
    The Effects of Maternal Smoking on Thyroid Function: Findings from Routine First-Trimester Sonographic Anomaly Screening
    (2023-01-01) BAKAR R. Z.; ÇETİN Ç.; Yozgat C. Y.; KÜTÜK M. S.; BAKAR, RABIA ZEHRA; ÇETİN, ÇAĞLAR; KÜTÜK, MEHMET SERDAR
    Aim This study aimed to assess the effect of tobacco exposure on maternal thyroid function and investigate its relationship to subclinical hypothyroidism in pregnant women during the first trimester. Subjects and Method A comparison of maternal thyroid function was made on 45 smokers, who composed the study group, and 72 non-smokers, pregnant women, who constituted the control group. After determining smokers by questionnaire, carbon monoxide (CO) levels in the expiratory air of the participants in both groups were measured and recorded, and the smokers\" exposure was objectively confirmed. Results Smoking and non-smoking pregnant women were similar regarding body mass index (BMI). While the TSH and fT4 levels were respectively 1.48 mlU/L and 11.43 pmol/L in pregnant women who smoked, that ratio changed to 1.72 mlU/L and 11.17 pmol/L in the non-smokers\" group. But the differences between the groups were not statistically significant (p=0.239, p=0.179). Even though the rate of subclinical hypothyroidism was 8.9% in the smoking group, it was approximately 19.4% in the non-smoker group; the difference was not statistically significant (p=0.187). Conclusion This study proved that there is no statistically significant difference between maternal serum TSH and fT4 levels and the rate of subclinical hypothyroidism in smokers during pregnancy in the first trimester.
  • Publication
    Assessment of postpartum symphysis pubis distention with 3D ultrasonography: a novel method.
    (2016-03-01) Aydın, SERDAR; BAKAR, RABİA ZEHRA; AYDıN, ÇA; OZCAN, PINAR; AYDIN, SERDAR; BAKAR, RABIA ZEHRA; AYDIN, CEMALETTİN; ÖZCAN, PINAR
  • Publication
    Thel Incidence of Concomitant Precancerous Lesions in Cases Who Underwent Hysterectomy for Prolapse
    (2016-09-01T00:00:00Z) AYDIN, SERDAR; BAKAR, Rabia Zehra; Mammadzade, Aygun; DANSUK, RAMAZAN; AYDIN, SERDAR; BAKAR, RABIA ZEHRA; DANSUK, RAMAZAN
    The aim of the study was is to assess the incidence of unexpected gynecological cancers and pre-cancerous lesions following hysterectomy for pelvic organ prolapse to better understand the risks of uterine sparing surgery. Material and Method: This was a retrospective analysis of histopathology findings after hysterectomy for uterine prolapse surgery who underwent preoperative diagnostic work including cervical cytology, transvaginal ultrasonography and endometrial histopathological examination for a high risk group (Postmenopausal women with an endometrial thickness of >= 5 mm and premenopausal women with abnormal bleeding). Patients with a history of endometrial, cervical and/or adnexal precancerous or cancerous pathological conditions and with incomplete medical records were excluded. Results: Results were taken from 106 women who underwent hysterectomy. The abdominal route was used in 22 cases (21.7 %), the vaginal route in 82 patients (77.4 %) and laparoscopic-assisted vaginal route in two (1.9 %) women. Oophorectomy was performed in 35 (33 %) cases. None of the patients had malignant histopathology specimens from hysterectomy. Total premalignant pathology incidence was 7.5 % (8/106). Six (5.7%) patients had simple endometrial hyperplasia and 2 patients (1.9 %) had cervical intraepithelial neoplasia. Discussion: The incidence of unexpected endometrial, cervical or ovarian malignancy among women who underwent hysterectomy after preoperative diagnostic workup including transvaginal ultrasonograhy, endometrial pathological examination to high risk cases was negligible. The inclusion of low risk endometrial and cervical precancerous lesions increased the incidences. Our results could provide precious data to extrapolate to similar populations with uterine prolapse who desire surgical correction sparing uterus.
  • Publication
    The effects of maternal smoking on fetal cranial development. Findings from routine midtrimester sonographic anomaly screening
    (2023-12-01) ÇETİN Ç.; BAKAR R. Z.; Takmaz T.; PASİN Ö.; KÜTÜK M. S.; ÇETİN, ÇAĞLAR; BAKAR, RABIA ZEHRA; PASİN, ÖZGE; KÜTÜK, MEHMET SERDAR
    The aim of this study was to assess the effect of continued smoking before and during pregnancy on mid-trimester fetal head development. A total of 250 pregnant women enrolled in the study. All participants were confirmed to be smokers or non-smokers by verifying breath carbon monoxide readings. Biparietal diameter (BPD), head circumference (HC), lateral ventricle (LV), and cisterna magna (CM) were evaluated by ultrasound between 20-22 weeks of pregnancy. Gender and gestational age-adjusted BPD z- scores were not statistically different between smokers and non-smokers (-0.75 ± 1.6 vs -0.51 ± 1, p = .3). HC measurements and z- scores were significantly lower in the smoking group than in the non-smoking groups (183.38 ± 14.56 vs. 189.28 ± 12.53, p = .003, 0.18 ± 1.39 multiple of median (MoM) vs. 0.56 ± 0.92, respectively, p = .023). At linear regression analysis, maternal smoking was the only independent factor associated with fetal HC z score (p = .041). In conclusion, continued smoking during pregnancy reduces fetal HC and has no effect on BPD, LV, or CM measurements at mid-gestation.IMPACT STATEMENTWhat is already known on this subject? Smoking during pregnancy is one of the most common environmental factors affecting fetal and neonatal growth and well-being. Despite the well-known effects of smoking on somatic growth, current studies have shown that it selectively affects some parts of the fetal brain, even in appropriately growing fetuses.What do the results of this study add? Continued smoking during pregnancy reduces fetal HC and has no effect on BPD, LV or CM measurements at mid-gestation. Since smoking is well known for its early and late childhood behavioral and neurological consequences, smaller mid-trimester fetal HC measurements should bring maternal smoking to mind as one of the potentially reversible causes.What are the implications of these findings for clinical practice and/or further research? The harmful effects of smoking start before the third trimester and antenatal counseling should be started early in the gestation. Every effort should be made to quit smoking before or early in pregnancy.
  • Publication
    Sleep, depression, anxiety and fatigue in women with premature ovarian insufficiency
    (2022-05-01T00:00:00Z) ATEŞ, SEDA; Aydin, Serdar; ÖZCAN, PINAR; BAKAR, Rabia Zehra; ÇETİN, ÇAĞLAR; ATEŞ, SEDA; ÖZCAN, PINAR; BAKAR, RABIA ZEHRA; ÇETİN, ÇAĞLAR
    Purpose To assess sleep disturbances, levels of anxiety, depression and fatigue in women with premature ovarian insufficiency (POI). Materials and methods The study included 62 women with POI and 62 age-matched controls. Women in both groups completed questionnaires. Pittsburgh Sleep Quality Index, Insomnia severity index, Epworth Sleepiness Scale, Hospital Anxiety and Depression Scale and Fatigue Severity Scale were used. Results We found poor sleep quality, higher levels of insomnia in women with POI than in controls. Depression was much more prevalent and severe in POI women. Total anxiety score, the severity of anxiety and fatigue did not differ significantly between the groups. According to the multivariable logistic regression analysis, being married and having POI were associated with worse quality of sleep, and having more children was associated with an increase in depression levels in the whole cohort. Backward analysis showed that when POI status was taken as a reference, married women were at 6.5 fold increased risk of poor sleep quality. Conclusions Women with premature ovarian failure are more likely to suffer from poor sleep quality, insomnia and depression than healthy women.