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BİLGİN, MEHMET

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    Platelet Glycoprotein IIb/IIIa Receptor Controls the Pro-Angiogenic Effect of Platelet Releasate
    (2011-11-22T00:00:00Z) ARSHAD, Muhammad; STAEDELE, Michael; ASLAM, Muhammad; HUSSAIN, Imran; RIAZ, Muhammad A.; SEDDING, Daniel G.; Bilgin, MEHMET; PIPER, Hans M.; NOLL, Thomas; GUENDUEZ, Dursun; BİLGİN, MEHMET
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    MRI of Pancreas in Patients with Chronic Pancreatitis and Healthy Volunteers: Can Pancreatic Signal Intensity and Contrast Enhancement Patterns be Valuable Predictors of Early Chronic Pancreatitis?
    (2017-01-01) Bilgin, Sabriye Sennur; Bilgin, MEHMET; Toprak, HÜSEYİN; BURGAZLI, K. Mehmet; CHASAN, Ritvan; ERDOGAN, Ali; Balci, Numan Cem; BİLGİN, MEHMET; TOPRAK, HÜSEYİN
    Background: Chronic pancreatitis is a progressive inflammatory disease of the pancreatic parenchyma and ductal structures. Typical MR imaging features of chronic pancreatitis include dilatation of the main pancreatic duct and irregularities of branch pancreatic ducts that can be evaluated with MRCP, loss of the normal high signal intensity of the pancreatic parenchyma on T1-weighted images, and decreased enhancement on dynamic contrast-enhanced sequences.
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    T2 Signal Intensity of the Trigeminal Nerve: A New Diagnostic Criteria for Trigeminal Neuralgia?
    (2018-01-01) Hatiboglu, Mustafa A.; KAYA, Ozlem K.; Alkan, ALPAY; Timocin, GİZEM; BADUR, Bahar A.; Bilgin, MEHMET; ALKAN, ALPAY; HATİBOĞLU, MUSTAFA AZİZ; TİMOÇİN, GİZEM; BİLGİN, MEHMET
    Objectives: The objectives of this study were to: 1) compare the size and T2 signal intensity of the trigeminal nerves on the symptomatic side and asymptomatic side of the patients with idiopathic trigeminal neuralgia and to correlate these morphological findings with each other in order to assess whether Magnetic Resonance Imaging (MRI) can provide evidence of microstructural changes in the affected trigeminal nerve that could be potential imaging markers for diagnosis and monitoring trigeminal neuralgia 2) correlate these data with the pain score of the patients in order to search a quantitative evaluation method of the pain in patients with Trigeminal Neuralgia (TN).
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    Diagnosis and treatment of deep-vein thrombosis and approach to venous thromboembolism in obstetrics and gynecology.
    (2011-09-01T00:00:00Z) BURGAZLı, KM; Bilgin, MEHMET; KAVUKCU, E; ALTAY, MM; OZKAN, HAYDAR; COŞKUN, U; AKDERE, H; ERTAN, AK; BİLGİN, MEHMET; ÖZKAN, HAYDAR
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    Randomized Comparison of Multipolar, Duty-Cycled, Bipolar-Unipolar Radiofrequency Versus Conventional Catheter Ablation for Treatment of Common Atrial Flutter
    (2010-10-01T00:00:00Z) ERDOGAN, Ali; GUETTLER, Norbert; DOERR, Oliver; FRANZEN, Wolfgang; SOYDAN, Nedim; Bilgin, MEHMET; VOGELSANG, Pascal; PARAHULEVA, Mariana; TILLMANNS, Harald; STRACKE, Siegbert; GUENDUEZ, Dursun; NEUHOF, Christiane; BİLGİN, MEHMET
    Methods: Patients presenting to our department with symptomatic, typical AFL were enrolled consecutively and randomized to conventional RF ablation with an 8-mm tip catheter (ConvRF) or a duty-cycled, bipolar-unipolar RF generator delivering power to a hexapolar tip-versatile ablation catheter (T-VAC) group. For both groups, the procedural endpoint was bidirectional cavotricuspid isthmus block.
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    Acute left main coronary artery occlusion
    (2013-01-01T00:00:00Z) BURGAZLI, K. Mehmet; Bilgin, MEHMET; SOYDAN, Nedim; CHASAN, Ridvan; ERDOGAN, Ali; BİLGİN, MEHMET
    The treatment of an acute left main coronary artery occlusion still poses a challenge. In this case report we present a 50-year-old patient with an acute occlusion of the left main artery. After a successful angioplasty without -stenting- due to the complexity of the stenosis the patient underwent a successful bypass surgery. We discuss the therapeutic options of acute left main occlusion regarding medical, interventional and surgical options.
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    Iliofemoral-popliteal deep vein thrombosis at 35(th) week of pregnancy: treated with cesarean section and vena cava blockage plus thrombectomy.
    (2012-06-01T00:00:00Z) Mehmet, Burgazlı; ALTAY, MM; AKDERE, H; Bilgin, MEHMET; KAVUKCU, E; KILL, H; PÄFGEN, W; Kubilay, Ertan; BİLGİN, MEHMET
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    Inflammatory Fibroid Polyp of the Stomach Mimics Malignancy on 18F FDG PET/CT Imaging.
    (2016-09-01) BILGIN, SS; Bilgin, MEHMET; SAVAS, R; ERDOGAN, EZGİ BAŞAK; BİLGİN, MEHMET; ERDOĞAN, EZGİ BAŞAK
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    Bauhinia bauhinioides cruzipain inhibitor reduces endothelial proliferation and induces an increase of the intracellular Ca2+ concentration
    (2010-12-01T00:00:00Z) Bilgin, MEHMET; NEUHOF, Christiane; DOERR, Oliver; BENSCHEID, Utz; ANDRADE, Sheila S.; MOST, Astrid; ABDALLAH, Yaser; PARAHULEVA, Mariana; GUENDUEZ, Dursun; OLIVA, Maria L.; ERDOGAN, Ali; BİLGİN, MEHMET
    Proteinase inhibitors, isolated from different types of Bauhinia, have an effect on apoptosis, angiogenesis and inflammation. The Bauhinia bauhinioides cruzipain inhibitor (BbCI) is a Kunitz-type inhibitor and inactivates the cysteine proteinases cruzipain and cruzain from Trypanosoma cruzi. Cruzipain and tissue kallikrein have similar biochemical properties, e.g. the proteolytic cleavage of the kininogen precursor of lys-bradykinin. Tissue kallikrein stimulation in endothelial cells causes migration and capillary tube formation. The aim of this study was to examine whether the antiproliferative effect of BbCI is dependent on changes of the intracellular calcium concentration and membrane hyperpolarization. Endothelial cells were isolated from human umbilical cord veins (HUVEC). For proliferation experiments, HUVEC were incubated with BbCI (10-100 mu mol/L) for 48 h. The proliferation was detected by cell counting with a Neubauer chamber. The effect of BbCI (10-100 mu M) on the membrane potential was measured with the fluorescence dye DiBAC(4)(3) and the effect on [Ca+2] (i) with the fluorescence probe Fluo-3 AM. The change of the fluorescence intensity was determined with a GENios plate reader (Tecan). The experiments showed that BbCI (10-100 mu mol/L) reduces the endothelial cell proliferation significantly in a concentration-dependent manner with a maximum effect at 100 mu mol/L (35.1 +/- 1.8% as compared to control (p a parts per thousand currency signaEuro parts per thousand 0.05; n = 45)). As compared to the control, the addition of BbCI (100 mu mol/L) caused a significant increase of systolic Ca2+ of 28.4 +/- 5.0% after 30 min incubation. HUVEC treatment with BbCI (100 mu mol/L) showed a weak but significant decrease of the membrane potential of 9.5 +/- 0.9% as compared to control (p a parts per thousand currency signaEuro parts per thousand 0.05; n = 80). BbCI influenced significantly the endothelial proliferation, the intracellular Ca2+ concentration and the membrane potential.
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    Ultrasonography and magnetic resonance imaging findings of abdominal complications of cystic fibrosis.
    (2012-10-01) Bilgin, MEHMET; BURGAZLI, MEHMET; Toprak, HÜSEYİN; ERDOGAN, ALİ; KOCAKOÇ, ERCAN; BİLGİN, MEHMET; TOPRAK, HÜSEYİN