Person: ÇOBAN, GANİME
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Publication Effects of keto-analogs in the pathologic findings of diabetic nephropatic rats(2020-01-01T00:00:00Z) Kazancıoğlu, Rümeyza; Çoban, Ganime; Gürsu, Meltem; Elçioğlu, Ömer Celal; Deligöz Bilkdacı, Yelda; ÇOBAN, GANİME; GÜRSU, MELTEM; ELÇİOĞLU, ÖMER CELALPublication Can the use of reference pictures improve the interobserver variability on assessment of liver steatosis percentage: A digital platform based approach(2017-09-01) Turkmen, I. Cetinaslan; Cakir, A.; Capar, A.; Saka, B.; Kahraman, Z. S.; Erkan, S. Sengiz; Ozkan, Y.; Kepil, N.; Keser, S. Hallac; Gucin, Z.; Ceyran, B.; Coban, G.; Yilmaz, M. Segmen; Arici, S.; Dursun, N.; Dogusoy, G. Bulbul; Tuncel, D.; Ozguven, B. Yilmaz; Pasaoglu, E.; Kamali, G. Harman; Kirimlioglu, H.; Erdamar, S.; Yildiz, S.; Erdogan, N. Yildirim; Armutlu, A.; ÇOBAN, GANİME; ARICI, DILEK SEMAPublication Protective effect of dexpanthenol against nephrotoxic effect of amikacin: An experimental study(2017-05-01) Dogan, ELİF ECE; ERKOC, Reha; EKINCI, Iskender; HAMDARD, Jamshid; DONER, Baris; KARATOPRAK, CUMALİ; Coban, GANİME; Ozer, Omer Faruk; Kazancioglu, RÜMEYZA; DOĞAN, ELİF ECE; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZABackground: Amikacin has the largest spectrum among aminoglycosides, its nephrotoxic effect limits its utilization. Our purpose in this study is to review the protective effect of dexpanthenol against the nephrotoxic effect of amikacin, accompanied with histopathological and biochemical parameters.Publication Ungewöhnlicher Fall eines bilateralen kombinierten Netzhautvenen- und Arterienverschlusses, vermutlich aufgrund einer Blutegeltherapie durch Hirudo Medicinalis.(2023-12-07) Ağın A.; Oskan E. E.; Bastan Tuzun B.; Gocgun N.; Coban G.; Onder F.; ÇOBAN, GANİMEVorstellung eines Patienten, der aufgrund von Hirudo Medicinalis einen kombinierten Netzhautarterien- und Venenverschluss entwickelte. Eine 55-jährige Patientin wurde mit der Vordiagnose Pseudotumor cerebri in unsere Klinik überwiesen. In ihrer Anamnese wurde eine Woche zuvor eine Blutegeltherapie im Periokularbereich durchgeführt. Bei ihrer biomikroskopischen Untersuchung war die Fundoskopie mit einem bilateralen kombinierten Netzhautvenen- und Arterienverschluss vereinbar. In der kranialen Magnetresonanztomographie (MRT) wurde eine akute multiple Diffusionseinschränkung festgestellt. In der neuroradiologischen und neuropathologischen Beratung wurde ein Zusammenhang mit einem entzündlichen Prozess vermutet. Trotz aller ärztlichen Untersuchungen und Behandlungen konnte beim Patienten keine Verbesserung des Sehvermögens erreicht werden. Darüber hinaus wurden in der zweijährigen Nachuntersuchung keine systemischen Befunde festgestellt, die diese Situation erklären könnten. Es ist zu bedenken, dass ein kombinierter Netzhautvenen- und Arterienverschluss, der selten beobachtet wird, bei einem entzündlichen Prozess im Zusammenhang mit Hirudo Medicinalis auftreten kann. Abstract To present a patient who developed combined retinal artery and vein occlusion due to Hirudo medicinalis. A 55-year-old female patient was referred to our clinic with a pre-diagnosis of pseudotumor cerebri. In her history, leech therapy was applied to the periocular area a week before. On her biomicroscopic evaluation, fundoscopy was compatible with bilateral combined retinal vein and artery occlusion. Acute multiple diffusion restriction was detected in cranial magnetic resonance imaging (MRI). In neuroradiological and neuropathological consultation, the findings were thought to be associated with an inflammatory process. Despite all the medical evaluation and treatment, the patient could not achieve visual improvement. Besides, no systemic findings were detected in two years follow-up that could explain this situation. It should be kept in mind that combined retinal vein and artery occlusion, which is rarely observed, may be seen with an inflammatory process associated with Hirudo medicinalis.Publication Renal Biopsy in Patients with Diabetes: Indications, Results, and Clinical Predictors of Diabetic Kidney Disease(2021-02-01T00:00:00Z) Artan, Ayşe Serra; Kazancıoğlu, Rümeyza; Elçioğlu, Ömer Celal; Çoban, Ganime; Gürsu, Meltem; GÜRSU, MELTEM; ÇOBAN, GANİME; ELÇİOĞLU, ÖMER CELAL; KAZANCIOĞLU, RÜMEYZAPublication Does ozone administration have a protective or therapeutic effect against radiotherapy-induced testicular injury?(2019-03-01) AYDOĞDU, İBRAHİM; İLBEY, YUSUF ÖZLEM; ÇOBAN, GANİME; EKİN, RAHMİ GÖKHAN; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALİ; KIZILTAN, HURİYE ŞENAY; EKİN, ZÜBEYDE YILDIRIM; SILAY, MESRUR SELÇUK; SEMERCİ, MEHMET BÜLENT; AYDOĞDU, İBRAHİM; ÇOBAN, GANİME; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALI; KIZILTAN, HURİYE ŞENAYObjective: We investigate the protective and therapeutic effects of ozone therapy (OT) in radiotherapy (RT)‑induced testicular damage. Methods: Thirty healthy adult male Wistar rats divided into five groups consisting of six animals each as follows: (1) Control (C), (2) RT, (3) OT, (4) OT + RT, and (5) RT + OT group. Histopathological findings, Johnsen scores, thiobarbituric acid‑reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) levels were evaluated. Results: RT caused a significant decrease in testicular weight and Johnsen score compared to the control group. In addition, TBARS level was significantly higher, whereas GSH, SOD, catalase, and GPx levels were significantly lower in the RT group when compared to the control group. Pre and postRT OT significantly increased GSH, SOD, catalase, and GPx levels and decreased TBARS level. Furthermore, testicular weight and Johnsen score were increased with OT. Conclusions: The present study showed that OT is protective and therapeutic in radiation‑induced testicular damage. OT may be beneficial to the patients who underwent RT.Publication The Relationship of Prognostic Factors with Regulatory T Cells in Langerhans Cell Histiocytosis(2023-12-01) Çoban G.; Coşanay Tekden B.; Güler B.; Çakır F. B.; Toluk Ö.; Gücin Z.; Elagöz Ş.; ÇOBAN, GANİME; COŞANAY TEKDEN, BÜŞRA; GÜLER, BERIL; ÇAKIR, FATMA BETÜL; GÜCİN, ZÜHAL; ELAGÖZ, ŞAHANDEPublication Undifferentiated Embryonal Sarcoma of the Liver in an Adult: Case Report(2016-03-01) ÇOBAN, GANİME; GÜCİN, ZÜHAL; Karatepe, Oğuzhan; Kocakoç, Ercan; ÇOBAN, GANİME; GÜCİN, ZÜHALPublication Mesane Tümörleri(2021-01-01T00:00:00Z) ÇOBAN, GANİME; ÇOBAN, GANİMEPublication Anti-CD10 (56C6) expression in soft tissue sarcomas(2012-01-01T00:00:00Z) DENİZ, Kemal; Coban, Ganime; Okten, Turhan; ÇOBAN, GANİMECD10 is known to be expressed in certain types of leukemia, in lymphomas and also in various types of carcinoma. However, data regarding CD10 expression in soft tissue sarcomas is scarce. Two hundred and two retrospective soft tissue sarcoma specimens were evaluated for CD10 expression immunohistochemically. The clinical records of these patients were reviewed, and clinical data was obtained for all patients. Our results showed that 90 of the 202 cases were found to express CD10. 72% of malignant fibrous histiocytomas, 45% of fibrosarcomas, 34% of rhabdomyosarcomas, 50% of leiomyosarcomas, 22% of liposarcomas, 72% of malignant peripheral nerve sheath tumors, and 0% of the primitive neuroectodermal tumors were positive for CD10. Nearly half of the soft tissue sarcomas were found to express CD10. Stronger CD10 expression was found in high grade sarcomas. (C) 2012 Elsevier GmbH. All rights reserved.