Person: ÖZDEMİR, MEHMET HAKAN
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Publication Metadata only Diyabetik Retinopati ve Makulopati(2021-05-01T00:00:00Z) Özdemir, Mehmet Hakan; Kırık, Furkan; ÖZDEMİR, MEHMET HAKAN; KIRIK, FURKANOptik Koherens Tomografi (OKT), retinanın yüksek çözünürlükte görüntülenmesine olanak sağlayan, girişimsel olmayan bir görüntüleme yöntemidir. Retinal patolojiler hakkındaki kantitatif ve kalitatif verileri diğer görüntüleme yöntemlerinden daha hızlı elde etmeye olanak sağlaması nedeniyle diyabetik retinopatinin (DR) tanı ve takibinde OKT’den giderek daha fazla yararlanılmaktadır. OKT’nin oftalmolojik, özellikle de DR-de, kullanımıyla birlikte birçok retinal lezyon daha ayrıntılı tanımlanmaya başlandı ve hatta bazı retinal değişiklikler ilk defa OKT ile gösterildi. Daha önce yapılan araştırmalar sonucunda, DR’ye bağlı tespit edilen bir takım patolojik bulguların tedavi yanıtı üzerine ve nihai görme keskinliği üzerine öngörülebilir sonuçlar verdiği tespit edildi ve bu bulgulara prognostik değer biçilerek çeşitli biyobelirteçler tanımlandı. Günümüzde artık DR’ye ait çeşitli komplikasyonların tanısında sıklıkla faydalandığımız OKT görüntülerinin hastaya ait klinik bulgular ile birlikte değerlendirilmesi, hem uygulanacak tedavinin erkenden belirlenebilmesi hem de hastalık prognozunun öngörülebilmesi açısından faydalı olacaktır.Publication Metadata only Ophthalmological Perspective on Pediatric Ear, Nose, and Throat Infections(Springer, London/Berlin , 2021-11-01) Kırık F.; Özdemir M. H.; KIRIK, FURKAN; ÖZDEMİR, MEHMET HAKANThe majority of the tissues and organs that fall into the area of expertise of ear, nose and throat (ENT) specialists are adjacent to the orbit, and therefore to the globe. As a result of this contiguity, ENT diseases can spread to the orbit and present with various orbital complications. While these complications can be mild, they can also manifest as severe morbidities that lead to permanent loss of vision. In addition, ENT diseases can also spread to the cranium as well as the orbit, and lead to severe intracranial complications that may result in mortality. Such intracranial complications may also manifest with findings in an ophthalmological examination, as many cranial nerves (CNs) are also associated with the orbital structures. This is why ENT specialists commonly encounter ophthalmological findings as a result of both the orbital and cranial complications of infectious ENT diseases. In addition, ophthalmological examination findings are useful for diagnosis, as some infectious agents can cause a common infection both in the ocular and head-neck region.Publication Metadata only Acute Phototoxic Retinopathy due to Infrared Heater(2020-09-01T00:00:00Z) Kırık, Furkan; Çevik, Neslihan; Bayraktar, Havvanur; Özdemir, Mehmet Hakan; KIRIK, FURKAN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANPublication Metadata only Relation of anatomy with function following the surgical treatment of idiopathic epiretinal membrane: a multicenter retrospective study(2020-11-01T00:00:00Z) ÖZDEK, ŞENGÜL; Ozdemir Zeydanli, Ece; Karabas, Levent; Teke, Mehmet Yasin; Yilmaz, Gursel; Citirik, Mehmet; Kocak, Nilufer; Durukan, Hakan; ÖZDEMİR, MEHMET HAKANPurpose To investigate the prognostic factors associated with functional and anatomical outcomes and to assess the longitudinal course of visual acuity and retinal morphology after vitreoretinal surgery for idiopathic epiretinal membrane (ERM). Methods This multicenter, retrospective study included a total of 634 eyes who underwent surgery for idiopathic ERM in 22 academic centers nationwide in Turkey. Data on best-corrected visual acuity (BCVA) and optical coherence tomography features (central foveal thickness (CFT), ERM and foveal contour morphology, ellipsoid zone (EZ) integrity) were collected and compared at baseline, 6-month, 12-month, and 24-month follow-ups. Prognostic factors for functional (having >= 20/25 Snellen BCVA) and anatomical (having normal/shallow foveal contour) recoveries after surgery were investigated by means of multivariate regression analyses. A cutoff value of preoperative BCVA optimizing functional recovery was calculated using receiver operating characteristic curve analysis. Results At a median follow-up of 24 months, 37.4% of the eyes achieved >= 20/25 BCVA and 54% regained normal or shallow foveal contour. Functional recovery was more likely in eyes with better baseline BCVA and intact EZ (R-2 = 0.356, p < 0.001). The cutoff baseline BCVA value for good visual prognosis was 0.35 logarithm of the minimum angle of resolution (Snellen 20/44) (sensitivity 60%, specificity 85%, p < 0.001). Anatomical recovery was negatively associated with advanced age, higher baseline CFT, foveal herniation-type ERM morphology, and internal limiting membrane (ILM) peeling (R-2 = 0.225, p < 0.001). The negative effect of ILM peeling on anatomical recovery was not significant after the first postoperative year (p = 0.05). Mean BCVA values and foveal morphology progressively improved at each visit. Cases with convex baseline foveal contour continued to change towards normal foveal depression over 24 months of follow-up, which took longer than the eyes with shallow/flat contoured cases. One-third of eyes with severe baseline EZ defects showed recovery at follow-up and achieved significantly greater visual acuity gains than the remaining eyes with persistent defects (p < 0.001). Conclusions Functional and anatomical restoration of the eyes appears to be a slow process after ERM surgery. This process may take much longer in eyes with worse foveal morphology at baseline. Although photoreceptor disruption may be reversible in some eyes, full functional recovery is unlikely when it persists.Publication Metadata only Diyabetik Retinopati ve Makülopati(Türkiye Klinikleri Yayınevi, 2021-05-01) Özdemir M. H.; Kırık F.; ÖZDEMİR, MEHMET HAKANOptik Koherens Tomografi (OKT), retinanın yüksek çözünürlükte görüntülenmesine olanak sağlayan, girişimsel olmayan bir görüntüleme yöntemidir. Retinal patolojiler hakkındaki kantitatif ve kalitatif verileri diğer görüntüleme yöntemlerinden daha hızlı elde etmeye olanak sağlaması nedeniyle diyabetik retinopatinin (DR) tanı ve takibinde OKT\"den giderek daha fazla yararlanılmaktadır. OKT\"nin oftalmolojik, özellikle de DR\"de, kullanımıyla birlikte birçok retinal lezyon daha ayrıntılı tanımlanmaya başlandı ve hatta bazı retinal değişiklikler ilk defa OKT ile gösterildi. Daha önce yapılan araştırmalar sonucunda, DR\"ye bağlı tespit edilen bir takım patolojik bulguların tedavi yanıtı üzerine ve nihai görme keskinliği üzerine öngörülebilir sonuçlar verdiği tespit edildi ve bu bulgulara prognostik değer biçilerek çeşitli biyobelirteçler tanımlandı. Günümüzde artık DR\"ye ait çeşitli komplikasyonların tanısında sıklıkla faydalandığımız OKT görüntülerinin hastaya ait klinik bulgular ile birlikte değerlendirilmesi, hem uygulanacak tedavinin erkenden belirlenebilmesi hem de hastalık prognozunun öngörülebilmesi açısından faydalı olacaktır.Publication Metadata only Spectral domain optical coherence tomography classification of diabetic macular edema: a new proposal to clinical practice.(2020-03-09T00:00:00Z) Arf, S; Sayman, Muslubas; Hocaoglu, M; Ersoz, Mg; Ozdemir, H; Karacorlu, M; ÖZDEMİR, MEHMET HAKANPublication Metadata only Güncel Vitreoretinal Cerrahi(2021-10-01T00:00:00Z) Özdemir, Mehmet Hakan; Ekinci, Cansu; ÖZDEMİR, MEHMET HAKAN; EKİNCİ, CANSUPublication Metadata only The relationship between preoperative anterior chamber parameters and postoperative refractive error in cataract surgery(2020-09-01T00:00:00Z) Koytak, İbrahim Arif; Kırık, Furkan; Özdemir, Mehmet Hakan; KIRIK, FURKAN; KOYTAK, İBRAHİM ARİF; ÖZDEMİR, MEHMET HAKANPurpose: Postoperative refraction has become important with improvements in cataract surgery. In this study, our aim was to investigate the effects of phacoemulsifi cation-intraocular lens (P-IOL) implantation on anterior chamber angle (ACA), anterior chamber volume (ACV), anterior chamber depth (ACD), and to assess relationship between these parameters and axial length (AL) and postoperative refractive error. Materials and Methods: We retrospectively reviewed data from 231 patients who underwent P-IOL implantation between January 2012 and June 2014. Scheimpfl ug imaging system was used for the determination of ACA, ACV and ACD values at preoperative and postoperative month 3. Partial coherence laser interferometry was used for preoperative AL, target postoperative refractive error and IOL power calculated by SRK-T formula. Spherical equivalent (SE=spherical error plus cylindrical error /2) at postoperative month 3 was recorded. Postoperative refractive error was calculated as mean error (ME=postoperative refraction-target refraction) and mean absolute error (MAE=absolute of ME). Data obtained at preoperative period and postoperative month 3 were compared. Results: Preoperative ACA, ACV, ACD were 30,2 ±12,1°, 130,7 ±41,2 mm³, 2,6 ±0,4 mm while postoperative ACA, ACV, ACD were 42,7 ±5,8°, 172,1 ±28,2 mm³, 4,1 ±0,7 mm respectively. Anterior chamber parameters were increased after P-IOL implantation, as all differences being statistically signifi cant (p=0.001). No signifi cant correlation was found between ME and ACA, ACV, ACD, AL. Again, no signifi cant correlation was found between MAE and ACA, ACV, ACD. Only a weak correlation was found between MAE and AL. Conclusion: Anterior chamber parameters measurements after P-IOL are signifi cantly increased compared to preoperative values. There was no signifi cant correlation between preoperative ACA, ACV, ACD and AL, and postoperative refractive error.Publication Metadata only Response to commentary -Retinal nerve fiber layer analysis in unaffected first-degree relatives of schizophrenia patients-.(2020-04-18T00:00:00Z) Ozdemir, MH; Kurtulmus, A; Elbay, AHMET; ELBAY, AHMET; ÖZDEMİR, MEHMET HAKANPublication Metadata only Fluorescein angiography as a primary guide for reduced-fluence photodynamic therapy for the treatment of chronic central serous chorioretinopathy.(2020-04-09T00:00:00Z) Koytak, A; Bayraktar, H; Ozdemir, H; KOYTAK, İBRAHİM ARİF; ÖZDEMİR, MEHMET HAKAN