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AKKOYUNLU, MUHAMMED EMİN

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MUHAMMED EMİN
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AKKOYUNLU
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Now showing 1 - 10 of 33
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    Evaluation of nephrotoxicity due to the use of colistimethate sodium in a intensive care unit
    (2013-09-01T00:00:00Z) AKKOYUNLU, MUHAMMED EMİN; Ceylan, Bahadir; AKKOYUNLU, YASEMİN; ÖZKAN, DİDEM; Ozcelik, Hatice; Aslan, Turan; Kart, Levent; AKKOYUNLU, MUHAMMED EMİN; AKKOYUNLU, YASEMİN; ÖZKAN, DİDEM
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    PublicationOpen Access
    The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea
    (2014-01-01) KILICARSLAN, Rukiye; Alkan, ALPAY; Sharifov, RASUL; Akkoyunlu, MUHAMMED EMİN; Aralasmak, AYŞE; KOCER, Abdulkadir; KART, Levent; ALKAN, ALPAY; SHARIFOV, RASUL; AKKOYUNLU, MUHAMMED EMİN; ARALAŞMAK, AYŞE
    Purpose: We investigated diffusion alterations in specific regions of the brain in morbid obese, obese, and nonobese OSA patients and searched whether there is a correlation between BMI and ADC values. Materials and methods: DWIs of 65 patients with OSA were evaluated. The patients were classified according to BMI as morbid obese (n = 16), obese (n = 27), and nonobese (control, n = 22) groups. ADC measurements were performed from 24 different regions of the brain in each patient. The relationship of BMI with ADC values was searched. Results: The ADC values in hypothalamus, insular cortex, parietal cortex, caudate nucleus, frontal white matter, and posterior limb of internal capsule were all increased in obese patients (n = 43) compared to control group. The ADC values of midbrain, hypothalamus, orbitofrontal cortex, and parietal cortex were significantly increased in morbid obese compared to obese patients. In obese patients, the degree of BMI was positively correlated with ADC values of orbitofrontal cortex, parietal cortex, and hypothalamus. Conclusion: We observed increasing brain vasogenic edema with increasing BMI, suggesting that the main reason of brain diffusion alteration in patients with OSA could be obesity related.
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    PublicationOpen Access
    Lung cancer, brucellosis and tuberculosis: Remarkable togetherness
    (2013-08-01) Akkoyunlu, MUHAMMED EMİN; AKKOYUNLU, YASEMİN; Hakyemez, Ismail Necati; Erboy, Fatma; ARVAS, Gulhan; ASLAN, Turan; AKKOYUNLU, MUHAMMED EMİN; AKKOYUNLU, YASEMİN; HAKYEMEZ, İSMAİL NECATİ
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    PublicationOpen Access
    [Relationship between symptoms of obstructive sleep apnea syndrome and traffic accidents in the city drivers].
    (2013-01-01) Akkoyunlu, MUHAMMED EMİN; KART, L; ULUDAĞ, M; Bayram, MEHMET; ALISHA, G; ÖZÇELIK, H; Karaköse, FATMANUR; SEZER, M; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Introduction: There is a high tendency for traffic accidents in patients with obstructive sleep apnea syndrome (OSAS). Thus it's recommended to investigate OSAS symptoms before certification of professional drivers. However, to what degree OSAS symptoms predict traffic accidents is not clear. We aimed to investigate the relationship between OSAS symptoms and traffic accidents. Materials and methods: Five hundred twenty bus drivers working at Istanbul Electricity, Tramway and Tunnel (IETT) general management were randomly selected. Berlin questionnaire was applied which included demographic data, accident ratios, total duration in profession, duration of working in a day and OSAS symptoms. Epworth sleepiness score (ESS) test was applied to assess day time slepiness. Results: All drivers were male. Snoring were present in 324 (65.7%) of participants. Traffic accident history were present in 259 (49.7%) of drivers. Significant relationship was present between traffic accident and only daytime sleepiness among the OSAS symptoms. The mean of accident/year ratio of all participants were 0.092. Mean of ESS was 7.3 ± 3.2 for all participants. There is a positive correlation between ESS and accident/year ratio (r= 0.57, p= 0.012). Conclusion: Only daytime sleepiness among OSAS symptoms is related with traffic accident. The questioning of OSAS symptoms alone is inadequate to estimate traffic accident risk. Thus further consideration more than symptom questioning is needed at phase of authorization of professional drivers to detect OSAS.
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    The effect of sleep apnea syndrome on the development of diabetic nephropathy in patients with type 2 diabetes
    (2012-10-01) Akkoyunlu, MUHAMMED EMİN; Kazancioglu, RÜMEYZA; Buyukaydin, BANU; OZCELIK, Hatice Kutbay; ERKOC, Reha; KART, Levent; BÜYÜKAYDIN, BANU; AKKOYUNLU, MUHAMMED EMİN; KAZANCIOĞLU, RÜMEYZA
    Aims: Type 2 diabetes mellitus and obstructive sleep apnea syndrome (OSAS) are serious comorbidities. Effects of OSAS on diabetic microvascular complications are ongoing research subjects. We evaluated the incidence of OSAS in Type 2 diabetes mellitus patients with nephropathy and with no renal involvement.
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    PublicationOpen Access
    [The frequency and properties of REM related obstructive sleep apnea among the patients with mild related obstructive sleep apnea].
    (2013-01-01) Kutbay, Özçelik; Akkoyunlu, MUHAMMED EMİN; BOSTANLı, P; Bayram, MEHMET; ATAHAN, E; SEZER, M; Karaköse, FATMANUR; KART, L; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Hafif obstrüktif uyku apneli hastalarda REM ile ilişkili obstrüktif uyku apne sıklığı ve özellikleri Giriş: REM ile ilişkili obstrüktif uyku apne (OUA), “Hafif ve orta OUA olgularında daha fazla görülmesi nedeniyle uykuda solunum bozuklukları spektrumunun erken bir işareti midir?” yoksa “Tamamen ayrı bir antite midir?” sorusuyla araştırmacıların son zamanlarda oldukça dikkatini çekmektedir. Bu çalışmada, hafif OUA tanılı hastalar arasında REM ile ilişkili OUA hastalarının sıklığını ve diğer hafif OUA tanılı hastalardan farkını görmek; ayrıca REM ile ilişkili OUA hastalarında gündüz aşırı uykululuk ile apne ilişkisini değerlendirmek amaçlanmıştır. Materyal ve Metod: 1 Ağustos 2010 ile 29 Şubat 2012 tarihleri arasında Bezmialem Vakıf Üniversitesi Uyku Laboratuvarında polisomnografi tetkiki yapılan toplam 1267 hasta arasından, 134 hafif OUA [Apne hipopne indeksi (AHİ)= 5-15] tanılı hasta retrospektif olarak değerlendirildi. REM AHİ/non-REM AHİ ≥ 2 olan ve non-REM AHİ < 15 olanlar; REM ile ilişkili OUA olarak kabul edildi. Bulgular: Toplam 134 hafif OUA tanılı hastadan 80 (%59)’i REM ile ilişkili OUA olarak değerlendirildi. REM ilişkili OUA ve diğer hafif OUA’lılar yaş, cinsiyet, gündüz aşırı uykululuk, beden kitle indeksi, boyun çevresi ve ek hastalık varlığı açısından karşılaştırıldığında; REM ile ilişkili OUA grubunda yalnızca yaş ortalaması anlamlı olarak düşük bulundu. REM ile ilişkili OUA grubunun %87.3’ünde REM AHİ 15’in üzerinde; %39.3’ünde 30’un üzerindeydi. REM ile ilişkili OUA olgularında; REM AHİ ile gündüz aşırı uykululuk semptomu arasında anlamlı ilişki saptanmadı (p= 0.81). Sonuç: Hafif OUA olguları arasında, REM ile ilişkili OUA grubunun yaş ortalamasının daha düşük olması, REM OUA’nın “uykuda solunum bozuklukları spektrumunun erken bir işareti” olabileceğini düşündürebilir. Bu grup hastaların klinik takibinin bu sorunun cevabı açısından yararlı olacağı kanısındayız.
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    Does CPAP treatment lead to gastroesophageal reflux in moderate and severe OSA case.
    (2014-09-01) OZCELIK, Hatice Kutbay; DANALIOGLU, Ahmet; Bayram, MEHMET; Akkoyunlu, MUHAMMED EMİN; YAKAR, Fatih; KARAKOSE, Fatmanur; SEZER, Murat; BAYRAM, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR
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    Asbestos-Related Diseases in Turkey: Not Only Caused by Naturally Occurring Fibers, but Also by Industrial Exposures
    (2018-12-01) Mehmdi, Elnur; BAYRAM, MEHMET; ÖZKAN, DİDEM; Bilgin, Sabriye Şennur; BİLGİN, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR; KANSU, ABDULLAH; BAYRAM, MEHMET; ÖZKAN, DİDEM; HAYAT, ESAT; BİLGİN, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR; KANSU, ABDULLAH
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    Pulmonary Thromboembolism in Klinefelter-s Syndrome Patient with Deficient of Protein C
    (2013-08-01T00:00:00Z) Yigit, Mehmet; Turkdogan, Kenan Ahmet; Akkoyunlu, Muhammed Emin; Lisar, Hazar; Erturk, Zeynep; AKKOYUNLU, MUHAMMED EMİN
    Kinefelter syndrome (KS) is a common genetic disorder caused by one or more supernumerary X chromosomes. KS poses an increased risk for venous thromboembolic events such as deep venous thrombosis and pulmonary embolism. Klinefelter syndrome is prone to hypercoagulability due to hormonal imbalance and one or more inherited thrombophilic factors. Therefore, patients with KS having a medical history of venous thromboembolism require chest computed tomographic (CT) images and oral anticoagulation therapy for a period of at least six months. A 21 year old, male patient diagnosed with Klinefelter syndrome was presented to the emergency department of our hospital with primary complaints of left lower extremity pain lasting for 2 months. Deep venous thromboembosis (DVT) was diagnosed via venous doppler ultrasound and pulmonary thromboembolism in his chest CT images. Following anticoagulation treatment, his symptoms recovered. An endocrinologic test should be ordered in patients having klinefelter syndrome with a medical or familial history of venous thromboembolism as well as additional assessment of innate or acquired thrombophilia should be made.
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    COPD: an underdiagnosed disease at hospital environment
    (2014-02-01) Kart, Levent; Akkoyunlu, MUHAMMED EMİN; Bayram, MEHMET; YAKAR, Fatih; OZCELIK, Hatice Kutbay; KARAKOSE, Fatmanur; SEZER, Murat; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Background and Aim Chronic obstructive pulmonary disease (COPD) is a serious disease with morbidity and mortality due to delayed diagnosis until significant symptoms arise. We aimed to assess the utility of spirometry and COPD Assessment Test (CAT) in detecting undiagnosed COPD patients in a localized area.