Person: AKDEMİR, OSMAN CEMİL
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Publication Open Access Persistent pleural effusion in an infant with an unusual diagnosis: congenital alveolar rhabdomyosarcoma(2020-01-01T00:00:00Z) Yozgat, Can Yilmaz; YEŞİLBAŞ, Osman; YOZGAT, Yılmaz; AKDEMİR, OSMAN CEMİL; YURTSEVER, İsmail; TEKİN, NUR; BAGHISHOV, DAMAT; BAYRAMOVA, NİGAR; ELAGÖZ, Şahande; ÇAKIR, FATMA BETÜL; YEŞİLBAŞ, OSMAN; YOZGAT, YILMAZ; AKDEMİR, OSMAN CEMİL; YURTSEVER, İSMAİL; TEKİN, NUR; BAGHISHOV, DAMAT; BAYRAMOVA, NİGAR; ELAGÖZ, ŞAHANDE; ÇAKIR, FATMA BETÜLRhabdomyosarcoma (RMS) is a malignant form of neoplasm that originates from skeletal muscle. RMSs can exist anywhere in the human body but are more commonly detected in the neck region and extremities. The alveolar type is one of the subtypes of RMS that has a poor prognosis. Because the clinical manifestation of a tumour can be a painless mass, symptoms might be non-contributary to the diagnosis. Herein, a four-month-old girl was admitted to the emergency department with complaints of respiratory distress without a runny nose, cough, and fever. Recurrent effusions subsided with subsequent tube thoracostomy. Video-assisted thoracoscopic surgery (VATS) was performed to determine the aetiology of the recurrent effusion. The Tru-Cut biopsy obtained during VATS resulted in the diagnosis of alveolar rhabdomyosarcoma. Pleural effusion decreased, and the tube drainage was stopped rapidly after first vincristine, actinomycin-D, and cyclophosphamide chemotherapy cycle. Persistent and recurrent pleural effusions should alert physicians to rule out unusual diagnoses like that of our case.Publication Open Access Merkel Cell Carcinoma(2023-01-01) Sönmez Ergün, Selma ; Kirazoğlu, Ahmet; Akdemir, Osman Cemil; Su Küçük, Özlem; Altınok, Pelin; Yıldız, Pelin; ERGÜN, SELMA; AKDEMİR, OSMAN CEMİL; KİRAZOĞLU, AHMET; YILDIZ, PELİN; SU KÜÇÜK, ÖZLEM; ALTINOK SÜT, PELİNMerkel cell carcinoma (MCC) is a rare tumor that arises from mechanoreceptor Merkel cells. Ultraviolet exposure, immunosuppression and Merkel cell polyoma virus play a significant role in tumor pathogenesis. Although it typically presents as an initially indolent growing, painless solitary lesion, the course of MCC may be aggressive due to the nodal invasion, distant metastasis and high recurrence rates. We presented a case of MCC with a background history of rheumatoid arthritis treated with immunosuppressive therapy for many years who had necrotizing granulomatous lymphadenitis.