2020-02-25T00:00:00Z, Türk, HM, Gültekin, MEHMET ALİ, Uysal, Ö, Beşiroğlu, M, Yilmaz, TF, Yurtsever, I, GÜLTEKİN, MEHMET ALİ, TÜRK, HACI MEHMET, TOPRAK, HÜSEYİN, YURTSEVER, İSMAİL, YILMAZ, TEMEL FATİH, SHARIFOV, RASUL, UYSAL, ÖMER

Purpose: We aimed to investigate whether there are any differences in apparent diffusion coefficient (ADC) values obtained from colorectal liver metastases (CRLM) according to Kirsten rat sarcoma (KRAS) gene mutation status.

2022-01-01T00:00:00Z, YILMAZ, TEMEL FATİH, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, GÜCİN, ZÜHAL, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA, YILMAZ, TEMEL FATİH, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, GÜCİN, ZÜHAL, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA

To evaluate breast MRI and DWI and demographic features of pleomorphic invasive lobular carcinoma (pILC) and classic invasive lobular carcinoma (cILC). Invasive lobular (ILC) is the second most common breast malignancy after invasive ductal carcinoma (IDC) and constitutes the 8-14% of all invasive breast cancers. ILC morphologically can be classified into the classic, alveolar, solid, tubulolobular, and pleomorphic subtypes according to WHO. This study was performed retrospectively. The MRI and demographic features of 18 patients with 23 pILC were compared with those 22 consecutive patients with 27 cILC. There was no significant difference in demographic features of patients, MR appearance, kinetics, and ADC values between two groups. pILC, an aggressive subtype of ILC, cannot be differentiated from cILC with breast MRI.

2019-05-01, Yilmaz, TEMEL FATİH, Aralasmak, AYŞE, Toprak, HÜSEYİN, MEHDI, Elnur, KOCAMAN, Gulsen, Kurtcan, SERPİL, Kaya, MEHMET ONUR, Alkan, ALPAY, YILMAZ, TEMEL FATİH, ARALAŞMAK, AYŞE, TOPRAK, HÜSEYİN, KURTCAN, SERPİL, KAYA, MEHMET ONUR, ALKAN, ALPAY

Purpose To search for CSF dynamics of idiopathic intracranial hypertension (IIH) and communicating hydrocephalus and any correlation between MRI findings, CSF metrics and CSF opening pressure in IIH.

2017-04-27, TOPRAK, HÜSEYİN, Yılmaz, Temel Fatih, Mehdi, Elnur, Kocaman, Gülsen, KAYA, MEHMET ONUR, ALKAN, ALPAY, TOPRAK, HÜSEYİN, ARALAŞMAK, AYŞE, YILMAZ, TEMEL FATİH, ALKAN, ALPAY

2018-07-01, Yilmaz, TEMEL FATİH, Aralasmak, AYŞE, Toprak, HÜSEYİN, GULER, Serhat, Tüzün, Umit, Alkan, ALPAY, YILMAZ, TEMEL FATİH, ARALAŞMAK, AYŞE, TOPRAK, HÜSEYİN, ALKAN, ALPAY

Heat stroke is the outcome of over heat stress that results in multiorgan dysfunction with a tendency for central nervous system damage. Brain is very sensitive to hyperthermia, especially the cerebellum that has selective vulnerability to heat stroke. There is complex interaction between heat cytotoxicity, coagulation disorder, cytotoxine - mediated systemic inflammatory response causing multiorgan failure, metabolic derangement, and circulatory insufficiency. We reviewed the literature and discussed brain MRI and MR spectroscopy findings of heat stroke, detailed the pathophysiology underlying brain involvement and proposed excitotoxic injury as an alternative mechanism of brain damage in heat stroke.

2019-11-01T00:00:00Z, Kiran, T, Peker, A, Yilmaz, TF, Yildiz, S, TOPRAK, HÜSEYİN, YILMAZ, TEMEL FATİH, KIRAN, TUĞÇE, YILDIZ, ŞEYMA

2014-01-01, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, Bilsel, Kerem, ÖZDEMİR, HÜSEYİN, ARALAŞMAK, AYŞE, ALKAN, ALPAY, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, BİLSEL, İSMAIL KEREM, ÖZDEMİR, HÜSEYIN, ARALAŞMAK, AYŞE, ALKAN, ALPAY

2022-01-01T00:00:00Z, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA

Aim: We aimed to investigate the magnetic resonance imaging (MRI) features of benign, atypical, or malignant papillary breast lesions and to assess the additional value of diffusion-weighted imaging (DWI) and turbo inversion recovery magnitude (TIRM) sequences to routine breast MRI. Background: Differentiation between benign and malignant papillary breast lesions is essential for patient management. However, morphologic features and enhancement patterns of malignant papillary lesions may overlap with those of benign papilloma. Methods: Seventy-two papillary breast lesions (50 benign, 22 atypical or malignant) were included in the current study, retrospectively. We divided the patients into two groups: benign papillary breast lesions and atypical or malignant papillary breast lesions. Morphologic, dynamic, turbo inversion recovery magnitude (TIRM) values and diffusion features of the papillary lesions were compared between two groups. Results: Benign papillary lesions were smaller in size (p=0.006 and p=0.005, for radiologists 1 and 2 respectively), closer to the areola (p=0.045 and 0.049 for radiologist 1 and 2 respectively), and had higher ADC values (p=0.001 for two radiologists) than the atypical or malignant group. ROC curves showed diagnostic accuracy for ADC (AUC=0.770 and 0.762, p & lt; 0.0001 for two radiologists), and showed a cut-off value of <= 957 x 10-6 mm(2/s) (radiologist 1) and <= 910 x 10-6 mm(2/s) (radiologist 2). Conclusion: MRI is a useful method for differentiation between benign and malignant papillary breast lesions. Centrally located, lesser in size, and higher ADC values should be considered benign, whereas peripherally located, larger in size, and lower ADC values should be considered malignant.

2021-12-22T00:00:00Z, Yilmaz, TEMEL FATİH, Gultekin, Mehmet Ali, Turk, Hacı Mehmet, Cesme, Dilek Hacer, Besiroglu, Mehmet, Simsek, Melih, Toprak, Huseyin, Alkan, ALPAY, YILMAZ, TEMEL FATİH, TÜRK, HACI MEHMET, ÇEŞME, DİLEK HACER, ŞİMŞEK, MELİH, ALKAN, ALPAY, TOPRAK, HÜSEYİN

Background: We aimed to investigate whether there is a difference between intrahepatic cholangiocarcinoma (IHCC) and liver metastases of gastrointestinal system (GIS) adenocarcinoma in terms of apparent diffusion coefficient (ADC) values. Patients and methods: From January 2018 to January 2020, we retrospectively examined 64 consecutive patients with liver metastases due to gastrointestinal system adenocarcinomas and 13 consecutive IHCC in our hospital's medical records. After exclusions, fifty-three patients with 53 liver metastases and 10 IHCC were included in our study. We divided the patients into two groups as IHCC and liver metastases of GIS adenocarcinoma. For mean apparent diffusion coefficient (ADCmean) values, the region of interests (ROI) was placed in solid portions of the lesions. ADCmean values of groups were compared. Results: The mean age of IHCC group was 62.50 ± 13.49 and mean age of metastases group was 61.15 ± 9.18. ADCmean values were significantly higher in the IHCC group compared to the metastatic group (p < 0.001). ROC curves method showed high diagnostic accuracy (AUC = 0.879) with cut-off value of < 1178 x 10-6 mm2/s for ADCmean (Sensitivity = 90.57, Specificity = 70.0, positive predictive value [PPV] = 94.1, negative predictive value [NPV] = 58.3) in differentiating adenocarcinoma metastases from IHCC. Conclusions: The present study results suggest that ADC values have a potential role for differentiation between IHCC and GIS adenocarcinoma liver metastases which may be valuable for patient management.

2018-03-01T00:00:00Z, TOPRAK, HÜSEYİN, YILMAZ, TEMEL FATİH, YILDIZ, ŞEYMA, Turkmen, Ihsan, Kurtcan, Serpil, TOPRAK, HÜSEYİN, YILMAZ, TEMEL FATİH, YILDIZ, ŞEYMA, KURTCAN, SERPİL