Person: ERCAN, ÇİLEM
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Publication Metadata only Effects of boric acid-linked ampicillin on the rat intra-abdominal sepsis model(2019-03-01T00:00:00Z) Idiz, Ufuk Oguz; Aysan, Erhan; Firat, Deniz; ERCAN, ÇİLEM; Demirci, Selami; Sahin, Fikrettin; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEMThe aim of this study was to determine efficiency of a new molecule that was obtained by linking boric acid with ampicillin in treating intra-abdominal infection. Following intraperitoneal E. coli injection totwenty-one female Wistar albino rats, group 1 was administered boron-linked ampicillin, group 2 was administered only ampicillin and group 3 was injected intraperitoneally with physiological serum. IL-6, and a white blood cell analysis was performed from the blood before and on the seventh day of treatment. No statistically significant difference in blood WBC levels after treatment was found among the groups. There was no statistically significant difference in the IL-6 values of group 2 and group 3 before and after the treatment (p=0.195 and 0.193, respectively); however, the reduction in the serum IL-6 values of group 1 was statistically significant (p=0.003). Boric acid-linked ampicillin is a more effective intra-abdominal infection treatment compared with ampicillin alone.Publication Metadata only . Paratiroid Doku Transplantasyonu, Türkiye’de Bir İlk. Hayata Bağış Dergisi(2014-03-01) AYŞAN, MUSTAFA ERHAN; gök, özlem; ALTUĞ, BURCUGÜL; ERCAN, ÇİLEM; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEMPublication Metadata only Parathyroid Allotransplant for Persistent Hypocalcaemia: A New Technique Involving Short-Term Culture. Experimental and clinical transplantation(2016-11-01) KILIÇ, ÜLKAN; AYŞAN, MUSTAFA ERHAN; gök, özlem; ALTUĞ, BURCUGÜL; ERCAN, ÇİLEM; İDİZ, UFUK OĞUZ; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEMPublication Open Access Parathyroid Allotransplant With a New Technique: A Prospective Clinical Trial.(2016-08-01) Aysan, E; ALTUG, B; ERCAN, C; Kesgin, Toka; IDIZ, UO; MUSLUMANOGLU, M; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEMObjectives: Parathyroid allotransplant is a valuable alternative in treating permanent hypoparathyroidism. However, it is a difficult process that requires several trained staff and advanced laboratory equipment, which makes the costs high. Here, we identify a new parathyroid allotransplant technique. Materials and Methods: After obtaining informed consent from patients, parathyroid cell suspensions obtained from 4 donors who had undergone a subtotal parathyroidectomy owing to chronic renal failure were transplanted in 10 patients with permanent hypoparathyroidism after short-term cell cultivation. Prednisolone were used as immunosuppressant for the first 10 days and discontinued thereafter. Results: Allograft function was observed in 7 patients (70%) at a mean follow-up of 12 months. Daily oral calcium and vitamin D supplementations discontinued totally in 7 patients. No major or minor complication was observed. Conclusions: Our technique is simple, fast, and has a low cost, with a 70% success rate at a mean follow-up of 12 months. It requires few staff, minimal equipment, and short-term immunosuppressant use for main tenance. The technical developments of parathyroid allotransplant, as mentioned in this study, may be important in treating permanent hypoparathyroidismPublication Metadata only Parathyroid Allotransplantation without Continuous Immunosupression prospective clinical series on 44 cases(2016-09-01) AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEM; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEM; AKBAŞ, FAHRİPublication Open Access Parathyroid Allotransplant for Persistent Hypocalcaemia: A New Technique Involving Short-Term Culture.(2016-04-01) Aysan, E; KILIC, U; GOK, O; ALTUG, B; ERCAN, C; Kesgin, Toka; IDIZ, UO; MUSLUMANOGLU, M; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEMObjectives: To develop a new parathyroid allotransplant method for the treatment of permanent hypoparathyroidism. Materials and methods: Parathyroid cells 50 × 10(6) derived from a parathyroid hyperplasia patient were transferred to a 61-year-old patient who had thyroidectomy 17 years earlier, allowing to papillary thyroid cancer; he was admitted to our outpatient clinic with symptomatic chronic hypocalcemia. Cell isolation, cryopreservation, and culturing were conducted according to a new protocol. Results: During a follow-up of 5 months, the patient had no complications that could indicate rejection, and clinical symptoms completely resolved without requiring any drug supplementation. Conclusions: Here, we report a new method, enabling fast and cost-effective parathyroid allotransplant with maintained tissue viability sufficient to treat persistent hypocalcemia.Publication Metadata only A novel non-surgical, minimally invasive technique for parathyroid autotransplantation: a case report.(2015-03-01) Aysan, E; KILIC, U; GOK, O; ALTUG, B; ERCAN, C; IDIZ, UO; KESGIN, C; MUSLUMANOGLU, M; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEMPublication Metadata only Parathyroid Allotransplant With a New Technique: A Prospective Clinical Trial.,Exp Clin Transplant.(2014-09-01) AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEM; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEMPublication Metadata only İmmunsupresyon uygulanmadan, hücre süspansiyonu olarak paratiroit allotransplantasyonu(2014-04-20) AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEM; AYŞAN, MUSTAFA ERHAN; ERCAN, ÇİLEM