Person: ARICI, DILEK SEMA
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Publication Metadata only Should Core Needle Biopsy be Used in the Evaluation of Thyroid Nodules?(2016-12-01) Guler, BERİL; Kiran, TUĞÇE; Arici, DİLEK SEMA; Aysan, Erhan; Sonmez, FATMA CAVİDE; GÜLER, BERIL; KIRAN, TUĞÇE; ARICI, DILEK SEMA; AYŞAN, MUSTAFA ERHAN; SÖNMEZ, FATMA CAVİDEFine needle aspiration (FNA) is the first choice in thyroid nodules suspected of harboring malignancy on sonography in routine practice. However, sampling with core needle biopsy (CNB) is also being used, especially in cases with repeated nondiagnostic/indeterminate diagnoses. The aim of this study was the retrospective evaluation of CNB samples. A total of 604 thyroid CNB samples registered in the Department of Pathology at Bezmialem Foundation University Medical Faculty within the 1-year period between June 2014 and June 2015 were re-evaluated by correlation with previous FNA and later resection results. CNB was divided into diagnostic groups of insufficient, malignant, suspicious for malignancy, no evidence of malignancy/benign, atypia of uncertain significance (AUS)/follicular lesions of uncertain significance (FLUS), and follicular neoplasm (FN)/suspicious for follicular neoplasm (SFN). Among the 604 cases, 15 cases (2.48 %) were classified as malignant and 9 cases (1.49 %) as suspicious for malignancy. No evidence of malignancy was seen in 512 cases (84.76 %). There were 26 (4.3 %) cases in the AUS/FLUS-FN/SFN group, and the sample was inadequate in 42 cases (6.95 %). Resection was performed for 17 of the cases classified as malignant or suspicious for malignancy, and all were found to be malignant. There were also 10 resected cases with a diagnosis of no evidence of malignancy, and all were found to be benign. We think that sampling with CNB may be useful especially in repeating inadequate biopsies or cases diagnosed with AUS/FLUS that have hesitations regarding clinical management. Larger series including comparisons with FNA and resection results are required.Publication Metadata only Apoptotic effects of topical antiglaucoma medications on conjunctival epithelium in glaucoma patients(2014-01-01) ARICI, MUSTAFA KEMAL; Arici, DİLEK SEMA; Ozec, Ayse Vural; DURSUN, AYHAN; TOKER, MUSTAFA İLKER; ERDOĞAN, HAYDAR; ARICI, MUSTAFA KEMAL; ARICI, DILEK SEMAPurpose: In this study, we aimed to investigate the apoptotic effects of topical antiglaucoma medications on the conjunctival epithelium.Publication Metadata only Mature ovarian cystic teratoma containing well-differentiated cerebellar tissue(2017-01-01) SONMEZ, F. Cavide; YILDIZ, PELİN; KIRAN, TUĞÇE; Arici, DİLEK SEMA; DANSUK, RAMAZAN; YILDIZ, PELİN; KIRAN, TUĞÇE; ARICI, DILEK SEMA; DANSUK, RAMAZANA 38-year-old female patient experienced groin pain; ultrasound imaging revealed a dermoid cystic mass in the right ovary and a cystectomy was then performed. Unusually, a mature cerebellum is found in the cyst wall. The pathological diagnosis was -mature cystic teratoma with well-differentiated cerebral and cerebellar tissue-. Glial tissue is a common neural component of teratomas, but a cerebellum is extremely rare in mature ovarian cystic teratomas. The authors report the case because of its rare component; they acknowledge that a cystic teratoma is the most common neoplasm of ovarian germ cells.