Person: DİNCEL, DEMET
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Ent-kaurane diterpenoids isolated from Sideritis congesta
2011-12-01, Topcu, GÜLAÇTI, Ertas, Abdulselam, Ozturk, Mehmet, Dincel, Demet, Kilic, Turgut, Halfon, Belkis, TOPÇU, GÜLAÇTI, DİNCEL, DEMET
A new ent-kaurane diterpenoid, together with eight known ent-kauranes, were isolated from the petroleum ether and acetone extracts of the whole plant of Sideritis congesta P. H. Davis & Hub.-Mor. and their structures were elucidated as the new compound ent-7 alpha-acetoxy-16 beta, 18-dihydroxy-kaurane (7-acetyldistanol) (1) and the known compounds ent-3 beta,7 alpha-dihydroxy, 18-acetoxy-15 beta,16 beta-epoxykaurane (epoxyisolinearol) (2), sideroxol (3), sideridiol (4), siderol (5), 7-epicandicandiol (6), foliol (7), linearol (8) and sidol (9). Characterization of compounds 1-9 was based on spectral analyses and comparison with reported data, particularly the new compound 1 was identified by 1D- and 2D-NMR and mass spectroscopic analyses. The antioxidant potential of the extracts, and also of the ent-kauranes except for 7, was investigated by three methods including beta-carotene bleaching method, free radical scavenging activity and superoxide anion scavenging activity. The anticholinesterase activity was also evaluated for the ent-kauranes except for 7, and most of the diterpenes exhibited weak acetylcholinesterase inhibitory activity. However, almost all diterpenes exhibited some inhibitory activity against butyrylcholinesterase; particularly, compounds 3 and 6 exhibited better BChE inhibitory activity than the standard compound galanthamine. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
A HPLC Method for Simultaneous Determination of Phenol and p-Cresol in Human UrineA HPLC Method for Simultaneous Determination of Phenol and p-Cresol in Human Urine
2013-08-16T00:00:00Z, Tekkeli, Şerife Evrim, Dincel, Demet, Önal, Armağan, Erkoç, Reha, Topçu, Gülaçtı, TEKKELİ, ŞERİFE EVRİM, DİNCEL, DEMET, TOPÇU, GÜLAÇTI
An HPLC Method for the Determination of Saxagliptin in Human Plasma with Fluorescence Detection
2013-12-01, Tekkeli, Şerife Evrim, Kızıltas, M. V., Dincel, Demet, TEKKELİ, ŞERİFE EVRİM, DİNCEL, DEMET
Passiflora incarnata L.’nin Bazı Biyolojik Aktivitelerinin İncelenmesi
2019-10-03T00:00:00Z, İğdeli, Gizem, Dincel, Demet, Kartal, Murat, Topçu, Gülaçtı, İĞDELİ, GİZEM, DİNCEL, DEMET, KARTAL, MURAT, TOPÇU, GÜLAÇTI
A High Performance Liquid Chromatography Method for the Determination of Meropenem in Serum
2019-10-01T00:00:00Z, Dincel, Demet, Sağırlı, Ahmet Olcay, Topçu, Gülaçtı, DİNCEL, DEMET, TOPÇU, GÜLAÇTI
Tilia cordata’nın Antioksidan ve Antikolinesteraz Aktivitelerinin İncelenmesi
2019-10-05T00:00:00Z, İğdeli, Gizem, Dincel, Demet, Gören, Ahmet Ceyhan, Topçu, Gülaçtı, İĞDELİ, GİZEM, DİNCEL, DEMET, GÖREN, AHMET CEYHAN, TOPÇU, GÜLAÇTI