2014-03-01T00:00:00Z, Cicekci, Mehtap, ONUR, MEHMET RUHİ, Aydin, Ayse Murat, Gul, Yeliz, ÖZKAN, YUSUF, AKPOLAT, NUSRET, KOCAKOÇ, ERCAN, KOCAKOÇ, ERCAN

The aim of this study was to evaluate the utility of apparent diffusion coefficient (ADC) values in differentiation between solid adrenal masses. The ADC values of 73 adrenal lesions (54 benign, 19 malignant) in 69 patients were measured at b 100, 600 and 1000 gradients on diffusion-weighted magnetic resonance imaging (DW-MRI). No statistically significant difference was found between ADC values of benign and malignant adrenal masses, nonadenomatous benign adrenal masses and malignant adrenal masses, adrenal adenomas and nonadenomatous lesions, adenomas and metastases, adenomas and pheochromocytomas, metastases and pheochromocytomas. ADC values are not helpful in the differentiation between solid adrenal masses. (C) 2014 Elsevier Inc. All rights reserved.

2011-12-01T00:00:00Z, ONUR, MEHMET RUHİ, Cicekci, Mehtap, Kayali, Alperen, KOCAKOÇ, ERCAN, Aygun, Cem, KOCAKOÇ, ERCAN

Purpose. The aim of this study was to investigate the diagnostic role of the apparent diffusion coefficient (ADC) measurement in the diagnosis of focal parenchymal lesions and to understand the discriminating role of the ADC value for differentiating Fasciola lesions from other focal liver lesions.

2015-01-01T00:00:00Z, KOCAKOÇ, ERCAN, Bakan, Ayse Ahsen, Poyrazoglu, Orhan Kursat, Dagli, Adile Ferda, Gul, Yeliz, Cicekci, Mehtap, BAHÇECİOĞLU, İBRAHİM HALİL, KOCAKOÇ, ERCAN

Objective: To examine the effectiveness of apparent diffusion coefficient (ADC) values and to compare the reliability of different b-values in detecting and identifying significant liver fibrosis. Subjects and Methods: There were 44 patients with chronic viral hepatitis (CVH) in the study group and 30 healthy participants in the control group. Diffusion-weighted magnetic resonance imaging (DWI) was performed before the liver biopsy in patients with CVH. The values of ADC were measured with 3 different b-values (100, 600, 1,000 s/mm(2)). In addition, liver fibrosis was classified using the modified Ishak scoring system. Liver fibrosis stages and ADC values were compared using areas under the receiver-operating characteristic (ROC) curve. Results: The study group-s mean ADC value was not statistically significantly different from the control group-s mean ADC value at b = 100 s/mm(2) (3.69 +/- 0.5 x 10(-3) vs. 3.7 +/- 0.3 x 10(-3) mm(2)/s) and b = 600 s/mm(2) (2.40 +/- 0.3 x 10(-3) vs. 2.5 +/- 0.5 x 10(-3) mm(2)/s). However, the study group-s mean ADC value (0.99 +/- 0.3 x 10(-3) mm(2)/s) was significantly lower than that of the control group (1.2 +/- 0.1 x 10(-3) mm(2)/s) at b = 1,000 s/mm(2). With b = 1,000 s/mm(2) and the cutoff ADC value of 0.0011 mm(2)/s for the diagnosis of liver fibrosis, the mean area under the ROC curve was 0.702 +/- 0.07 (p = 0.0015). For b = 1,000 s/mm(2) and the cutoff ADC value of 0.0011 mm(2)/s to diagnose significant liver fibrosis (Ishak score = 3), the mean area under the ROC curve was 0.759 +/- 0.07 (p = 0.0001). Conclusion: Measurement of ADC values by DWI was effective in detecting liver fibrosis and accurately identifying significant liver fibrosis when a b-value of 1,000 s/mm(2) was used. (C) 2015 S. Karger AG, Basel

2012-03-01T00:00:00Z, ONUR, MEHMET RUHİ, Cicekci, Mehtap, Kayali, Alperen, POYRAZ, AHMET KÜRŞAD, KOCAKOÇ, ERCAN, KOCAKOÇ, ERCAN

Purpose: To evaluate the utility of apparent diffusion coefficient (ADC) measurement in characterization of focal solid hepatic lesions and determine the role of ADC values in differentiation of solid benign and solid malignant hepatic lesions.