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KOCAKOÇ, ERCAN

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End date: 2015 × Start date: 2015 × Type: Article ×

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    PublicationOpen Access
    Assessment of Liver Fibrosis with Diffusion-Weighted Magnetic Resonance Imaging Using Different b-values in Chronic Viral Hepatitis
    (2015-01-01T00:00:00Z) KOCAKOÇ, ERCAN; Bakan, Ayse Ahsen; Poyrazoglu, Orhan Kursat; Dagli, Adile Ferda; Gul, Yeliz; Cicekci, Mehtap; BAHÇECİOĞLU, İBRAHİM HALİL; KOCAKOÇ, ERCAN
    Objective: To examine the effectiveness of apparent diffusion coefficient (ADC) values and to compare the reliability of different b-values in detecting and identifying significant liver fibrosis. Subjects and Methods: There were 44 patients with chronic viral hepatitis (CVH) in the study group and 30 healthy participants in the control group. Diffusion-weighted magnetic resonance imaging (DWI) was performed before the liver biopsy in patients with CVH. The values of ADC were measured with 3 different b-values (100, 600, 1,000 s/mm(2)). In addition, liver fibrosis was classified using the modified Ishak scoring system. Liver fibrosis stages and ADC values were compared using areas under the receiver-operating characteristic (ROC) curve. Results: The study group-s mean ADC value was not statistically significantly different from the control group-s mean ADC value at b = 100 s/mm(2) (3.69 +/- 0.5 x 10(-3) vs. 3.7 +/- 0.3 x 10(-3) mm(2)/s) and b = 600 s/mm(2) (2.40 +/- 0.3 x 10(-3) vs. 2.5 +/- 0.5 x 10(-3) mm(2)/s). However, the study group-s mean ADC value (0.99 +/- 0.3 x 10(-3) mm(2)/s) was significantly lower than that of the control group (1.2 +/- 0.1 x 10(-3) mm(2)/s) at b = 1,000 s/mm(2). With b = 1,000 s/mm(2) and the cutoff ADC value of 0.0011 mm(2)/s for the diagnosis of liver fibrosis, the mean area under the ROC curve was 0.702 +/- 0.07 (p = 0.0015). For b = 1,000 s/mm(2) and the cutoff ADC value of 0.0011 mm(2)/s to diagnose significant liver fibrosis (Ishak score = 3), the mean area under the ROC curve was 0.759 +/- 0.07 (p = 0.0001). Conclusion: Measurement of ADC values by DWI was effective in detecting liver fibrosis and accurately identifying significant liver fibrosis when a b-value of 1,000 s/mm(2) was used. (C) 2015 S. Karger AG, Basel
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    An unusual liver mass: primary malignant mesothelioma of the liver
    (2015-02-01T00:00:00Z) Serter, Asli; BÜYÜKPINARBAŞILI, NUR; Karatepe, Oguzhan; KOCAKOÇ, ERCAN; BÜYÜKPINARBAŞILI, NUR; KOCAKOÇ, ERCAN
    Primary malignant mesothelioma of the liver is extremely rare, and radiologic features have been defined in only one case. We present radiologic findings of two cases which are pathologically proven as primary malignant mesothelioma of the liver. Malignant mesothelioma of the liver may be included in a differential diagnosis list if there is a heterogeneous, hemorrhagic and necrotic lesion in the liver, with peripheral serpiginous vascular structures and increasing septal enhancement in post-contrast images.