Person: GÜRSOY, AZIZE ESRA
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Publication Metadata only The evaluation of vitamin D levels in patients with carpal tunnel syndrome(2016-07-01) Gursoy, AZİZE ESRA; Bilgen, HALİDE RENGİN; DURUYEN, Humeyra; ALTINTAS, Ozge; Kolukisa, MEHMET; Asil, TALİP; GÜRSOY, AZIZE ESRA; BİLGEN, HALİDE RENGİN; KOLUKISA, MEHMET; ASİL, TALIPThe aim of this study was to evaluate the relationship between 25-hydroxyvitamin D (25(OH)D) levels and carpal tunnel syndrome (CTS). 25(OH)D levels were checked in 108 consecutive patients with CTS symptoms and 52 healthy controls. All patients underwent nerve conduction studies and completed Boston Carpal Tunnel Questionnaire (BQ) symptom severity and functional status scales to quantify symptom severity, pain status and functional status. There were 57 patients with electrophysiological confirmed CTS (EP+ group) and 51 electrophysiological negative symptomatic patients (EP- group). 25(OH) D deficiency (25(OH)D < 20 ng/ml) was found in 96.1 % of EP- group, in 94.7 % of EP+ group and in 73.8 % of control group. 25(0H) D level was found significantly lower both in EP+ and EP- groups compared to control group (p = 0.006, p < 0.001, respectively). Although mean vitamin D level in EP- group was lower than EP+ group, statistically difference was not significant between EP+ and EP- groups (p = 0.182). BQ symptom severity and functional status scores and BQ pain sum score were not significantly different between EP+ and EP- groups. We found no correlation with 25(OH) D level for BQ symptom severity, functional status and pain sum scores. 25(OH) D deficiency is a common problem in patients with CTS symptoms. As evidenced by the present study, assessment of serum 25(OH)D is recommended in CTS patients even with electrophysiological negative results.Publication Metadata only Effects of botulinum toxin type a on quality of life assessed with the WHOQOL-BREF in hemifacial spasm and blepharospasm(2013-02-01T00:00:00Z) GÜRSOY, AZİZE ESRA; UGURAD, Işil; Babacan-Yildiz, Gülsen; KOLUKISA, MEHMET; ÇELEBI, Arif; GÜRSOY, AZIZE ESRA; BABACAN YILDIZ, GÜLSEN; KOLUKISA, MEHMETPublication Metadata only Both Legs and Arms are Restless Restless Extremities Syndrome(2014-07-01) KOLUKISA, MEHMET; BABACAN YILDIZ, gülsen; GÜRSOY, AZİZE ESRA; ASIL, TALİP; KOLUKISA, MEHMET; BABACAN YILDIZ, GÜLSEN; GÜRSOY, AZIZE ESRA; ASİL, TALIPPublication Metadata only Characteristic features of migraine in schoolchildren and adolescents and its relationship with autonomic nervous system disorders.(2013-10-01) TORUN, EMEL; Gursoy, E; GULER, S; KOLUKıSA, MEHMET; TATLI, B; TORUN, EMEL; GÜRSOY, AZIZE ESRA; KOLUKISA, MEHMETPublication Metadata only Neuromuscular transmission impairment in transient global amnesia(2013-10-01) Gursoy, AZİZE ESRA; BABACAN-YILDIZ, Gulsen; Kolukisa, MEHMET; Asil, TALİP; ERTAS, Mustafa; GÜRSOY, AZIZE ESRA; BABACAN YILDIZ, GÜLSEN; KOLUKISA, MEHMET; ASİL, TALIPPublication Open Access One-year follow-up in patients with brainstem infarction due to large-artery atherothrombosis(2015-01-01) Kolukisa, MEHMET; GUELTEKIN, Tugce Ozdemir; BARAN, Gozde Eryigit; Aralasmak, AYŞE; KOCAMAN, Guelsen; GUERSOY, Azize Esra; Asil, TALİP; KOLUKISA, MEHMET; ARALAŞMAK, AYŞE; GÜRSOY, AZIZE ESRA; ASİL, TALIPBackground: Posterior circulation infarction accounts for approximately 25% of the ischemic strokes. A number of different conditions may be associated with the development of brainstem infarction. Prognosis and recurrence rate of brainstem infarction due to large-artery atherothrombosis is still controversial. Methods: A total of 826 patients with ischemic stroke were admitted to our clinic during a 15-month period. Patients with clinical and radiological evidence of brainstem infarction were comprehensively assessed with appropriate vascular imaging modalities and for cardiological causes. Subjects with an established diagnosis of large-artery atherothrombosis were followed up for 1 year in terms of prognosis and recurrence rates. Results: Of the 101 patients with an established brainstem infarction, the diagnostic work-up indicated the presence of large-artery atherothrombosis as the causative factor in 53. A recurrent stroke was detected in the posterior circulation within the first 3 months in 5.8% and within 1 year in 9.8% of these individuals. The 1-year mortality rate was 11.7%. All patients with recurrent stroke had intracranial vascular narrowing at baseline. Conclusion: Our findings demonstrate a particularly high rate of recurrence and mortality at 1 year among patients who have a brainstem infarction due to intracranial arterial stenosis. Keywords: posterior circulation, intracranial arteries, extracranial arteries, stroke, vertebral artery, basilar arteryPublication Metadata only CREUTZFELDT-JAKOB DISEASE: A SINGLE CENTER EXPERIENCE AND SYSTEMIC ANALYSIS OF CASES IN TURKEY(2020-05-01T00:00:00Z) Uslu, Ferda; Gokcal, Elif; GÜRSOY, Azize Esra; KOLUKISA, MEHMET; Yildiz, Gulsen Babacan; USLU, FERDA; GÖKÇAL, ELİF; GÜRSOY, AZIZE ESRA; KOLUKISA, MEHMETIntroduction - We aimed to analyze the clinical, laboratory and neuroimaging findings in patients with sporadic Creutzfeldt-Jakob disease (CJD) in a single center as well as to review other published cases in Turkey.Publication Metadata only Reversible conduction failure in overlap of Miller Fisher syndrome and pharyngeal-cervical-brachial variant of Guillain-Barre syndrome in the spectrum of nodo-paranodopathies(2014-07-01) Gursoy, AZİZE ESRA; Kolukisa, MEHMET; ALTINTAS, Ozge; YAMAN, Asli; Asil, TALİP; GÜRSOY, AZIZE ESRA; KOLUKISA, MEHMET; BABACAN YILDIZ, GÜLSEN; ASİL, TALIPPatients with an overlap of the pharyngeal-cervical-brachial variant of Guillain-Barre syndrome and Miller Fisher syndrome (PCB/MFS) have rarely been reported. The electrophysiological findings in PCB/MFS are of great interest and may provide insight into the pathophysiology of the disorder. We report the clinical features and nerve conduction study findings in a patient with PCB/MFS with high titers of antiganglioside antibodies against GQ1b, GD1a, and GD1b. In serial nerve conduction studies, compound muscle action potential amplitudes normalised without development of temporal dispersion within 3 weeks, and absent median, ulnar, and sural sensory nerve action potentials became recordable within 4 months. These findings are consistent with reversible conduction failure in both motor and sensory fibres, and PCB/MFS could be classified in the recently described nodo-paranodopathy spectrum of acute neuropathies associated with anti-ganglioside antibodies. (c) 2013 Elsevier Ltd. All rights reserved.Publication Open Access Relationship between electrodiagnostic severity and neuropathic pain assessed by the LANSS pain scale in carpal tunnel syndrome.(2013-01-01T00:00:00Z) KOLUKISA, MEHMET; Gürsoy, AZİZE ESRA; YıLDıZ, GB; KOCAMAN, G; CELEBI, A; KOÇER, A; GÜRSOY, AZIZE ESRA; KOLUKISA, MEHMET; BABACAN YILDIZ, GÜLSENObjective: The aim of the study was to investigate the relationship between the presence of neuropathic pain assessed by the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale and electrophysiological findings in patients with carpal tunnel syndrome (CTS). Methods: We studied 124 hands with idiopathic CTS with pain complaints involving hand and wrist. All hands were assessed by the LANSS with which a score of 12 or more is defined as pain dominated by neuropathic mechanisms. These hands were assigned to minimal, mild, moderate, severe, or extreme severe groups according to the results of the median nerve conduction studies. Results: A LANSS score $ 12, suggestive of pain dominated by neuropathic mechanisms, was defined in 59 (47.6%) CTS hands. Pain intensity was significantly higher in CTS hands with a LANSS score $ 12 (P , 0.001). Among electrophysiological findings, compound muscle action potential amplitude was significantly lower in hands with a LANSS score $ 12 compared with hands with a LANSS score , 12 (P = 0.020). Severity of CTS was not significantly different between LANSS $ 12 and LANSS , 12 groups. Electrophysiological severity was significantly higher in CTS hands with evoked pain (P = 0.005) and allodynia (P , 0.001) in LANSS subscore analysis. Conclusion: We suggest that the presence of pain dominated by neuropathic mechanisms in CTS is not related to electrophysiological CTS severity. Neuropathic pain should be assessed carefully in patients with CTS, and an appropriate treatment plan should be chosen, taking into account the clinical and electrophysiological findings together with the true pain classification. Keywords: electrodiagnostic evaluation, carpal tunnel syndrome, LANSS, neuropathic painPublication Open Access Multiple Spontaneous Intracranial-Extracranial Arterial Dissections in a Patient with Osteogenesis Imperfecta(2017-01-01T00:00:00Z) KOLUKISA, MEHMET; GÖKÇAL, ELİF; GÜRSOY, Azize Esra; DENİZ, ÇİĞDEM; ARALAŞMAK, Ayşe; ASİL, Talip; KOLUKISA, MEHMET; GÖKÇAL, ELİF; GÜRSOY, AZIZE ESRA; DENİZ, ÇİĞDEM; ARALAŞMAK, AYŞE; ASİL, TALIPA 40-year-old male with osteogenesis imperfecta (OI) was admitted to the hospital with an acute right monoparesis. Diffusion-weighted MRI showed infarction in the territory of the left anterior cerebral artery (ACA) and in the left posterior cerebral artery (PCA). In his vascular imaging, occlusion of the left vertebral artery (VA) starting from V2 segment was consistent with dissection and pseudoaneurysm in the right ACA. We presented this case because of the presence of spontaneous and simultaneous occurrence of both intracranial and extracranial arterial dissections in OI.