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SOYSAL, PINAR

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PINAR
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SOYSAL
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Start date: 2011 × End date: 2019 × Author: Smith, L × Author: Veronese, N ×

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Now showing 1 - 9 of 9
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    PublicationOpen Access
    Prospective associations of cardiovascular disease with physical performance and disability : A longitudinal cohort study in the Osteoarthritis Initiative.
    (2019-11-05) Soysal, PINAR; Veronese, N; Stubbs, B; Koyanagi, A; Noventa, V; Bolzetta, F; Cester, A; Maggi, S; Jackson, SE; Loosemore, M; Demurtas, J; Smith, L; SOYSAL, PINAR
    Background Literature regarding cardiovascular disease (CVD) and incident physical performance limitations and disability in older people is equivocal. Aims This study aimed to investigate whether CVD is longitudinally associated with incident physical performance limitations and disability in a large population-based sample. Methods This was an 8-year prospective study using data collected as part of the Osteoarthritis Initiative. Participants were community-dwelling adults with knee osteoarthritis or at high risk for this condition. Diagnosed CVD was self-reported. Physical performance was assessed with measures of chair stand time and gait speed, whereas disability was assessed with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Longitudinal associations between CVD and changes in physical performance tests (chair stand time and gait speed) and disability score were analyzed using generalized linear models with repeated measurements. Results The analyzed sample comprised 4796 adults (mean age 61.2 years, 58.5% female), of whom 313 people (6.5%) reported CVD at baseline. During 8 years of follow-up, after adjustment for 11 potential confounders measured at baseline, those with CVD experienced a worse profile in chair stand time over the 8-year follow-up period than those without CVD (p= 0.006). Conclusion In a cohort of middle-aged and older adults with knee osteoarthritis or at high risk for this condition those with CVD experienced a worse profile in chair stand time over the 8-year follow-up period than those without CVD; however, CVD was not significantly associated with an increased incidence of poor gait speed and disability over 8 years of followup. Importantly, no associations were observed when utilizing propensity score matching.
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    PublicationOpen Access
    Is there a relationship between chocolate consumption and symptoms of depression? A cross-sectional survey of 13,626 US adults.
    (2019-10-01) Soysal, PINAR; Smith, L; Firth, J; Grabovac, I; Koyanagi, A; Hu, L; Stubbs, B; Demurtas, J; Veronese, N; Zhu, X; Yang, L; SOYSAL, PINAR
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    PublicationOpen Access
    Health behaviours and mental and physical health status in older adults with a history of homelessness: a cross-sectional population-based study in England.
    (2019-06-14) López-Sánchez, GF; Jackson, SE; Veronese, N; Moller, E; Johnstone, J; Firth, J; Grabovac, I; Yang, L; SOYSAL, PINAR
    Objectives: This study compared (1) levels of engagement in lifestyle risk behaviours and (2) mental and physical health status in individuals who have previously been homeless to those of individuals who have not. Design: Cross-sectional. Participants: Data were from participants (n=6931) of the English Longitudinal Study of Ageing. : Measures : Participants reported whether they had ever been homeless. We used regression models to analyse associations between homelessness and (1) cigarette smoking, daily alcohol consumption and physical inactivity, adjusting for sociodemographic covariates (age, sex, ethnicity, highest level of education, marital status and household non-pension wealth) and (2) self-rated health, limiting long-standing illness, depressive symptoms, life satisfaction, quality of life and loneliness, adjusting for sociodemographics and health behaviours. Results: 104 participants (1.5%) reported having been homeless. Individuals who had been homeless were significantly more likely to be physically inactive (OR 1.62, 95% CI 1.44 to 2.52), report fair/bad/very bad self-rated health (OR 1.75, 95% CI 1.07 to 2.86), have a limiting long-standing illness (OR 2.66, 95% CI 1.65 to 4.30) and be depressed (OR 3.06, 95% CI 1.85 to 5.05) and scored lower on measures of life satisfaction (17.34 vs 19.96, p<0.001) and quality of life (39.02 vs 41.21, p=0.013). Rates of smoking (20.2% vs 15.4%, p=0.436), daily drinking (27.6% vs 22.8%, p=0.385) and loneliness (27.1% vs 21.0%, p=0.080) were also elevated. Conclusions: Those who were once homeless have poorer mental and physical health outcomes and are more likely to be physically inactive. Interventions to improve their health and quality of life are required.
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    PublicationOpen Access
    The relationship between polypharmacy and trajectories of cognitive decline in people with dementia: A large representative cohort study.
    (2019-06-01) Perera, G; Onder, G; Petrovic, M; Cherubini, A; Maggi, S; Soysal, PINAR; Shetty, H; Molokhia, M; Isik, AT; Smith, L; Stubbs, B; Stewart, R; Veronese, N; Mueller, C; SOYSAL, PINAR
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    PublicationOpen Access
    Human Immunodeficiency Virus Infection and Diverse Physical Health Outcomes: An Umbrella Review of Meta-analyses of Observational Studies.
    (2019-08-11) Grabovac, I; Soysal, PINAR; Veronese, N; Stefanac, S; Haider, S; Koyanagi, A; Meilinger, M; ABBS, AD; Stubbs, B; McDermott, DT; Firth, J; Di, Gennaro; Demurtas, J; Jackson, SE; Yang, L; Smith, L; SOYSAL, PINAR
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    PublicationOpen Access
    Trends and prevalence of nocturia among US adults, 2005-2016.
    (2019-12-19) Isik, AT; Cao, C; Xu, T; Yang, L; Turan, Kazancioglu; Liu, Q; Pizzol, D; Veronese, N; Demurtas, J; Smith, L; SOYSAL, PINAR; KAZANCIOĞLU, RÜMEYZA
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    PublicationOpen Access
    Relationship Between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis.
    (2019-11-01) Soysal, PINAR; Pizzol, D; Demurtas, J; Stubbs, B; Mason, C; Isik, AT; Smith, L; Veronese, N; SOYSAL, PINAR
    Globally, there is increasing usage and legalization of cannabis. In addition to its reported therapeutic effects, cannabis has several health risks which are not clearly defined. Erectile dysfunction (ED) is the most common male sexual disorder and there are plausible mechanisms linking cannabis use to ED. No attempt has been made to collate the literature on this topic. The aim of this review was to summarize the prevalence and risk of ED in cannabis users compared to controls. A systematic review of major databases from inception to January 1, 2019, without language restriction, was undertaken to identify studies investigating cannabis use and presence of ED. The analysis compared the prevalence of ED in cannabis users versus controls. Consequently, the odds ratio (OR) with 95% confidence intervals (CI) was calculated, applying a random-effect model. Five case–control studies were included with data from 3,395 healthy men, 1,035 using cannabis (smoking) and 2,360 nonusers. The overall prevalence of ED in cannabis users was 69.1% (95% CI: 38.0–89.1), whilst the correspondent figure in controls was 34.7% (95% CI: 20.3–52.7). The OR of ED in cannabis users was almost four times that of controls (OR = 3.83; 95% CI: 1.30–11.28; p = .02), even if characterized by high heterogeneity (I2 = 90%) and the prediction intervals overlapped 1.00 (95% CI: 0.35–7.26). Data suggest that ED is twice as high in cannabis users compared to controls. Future longitudinal research is needed to confirm/refute this and explore if a dose–response relationship between cannabis and ED may be evident.
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    PublicationOpen Access
    The association of grip strength with depressive symptoms and cortisol in hair: A cross-sectional study of older adults.
    (2019-10-01) Smith, L; Firth, J; Grabovac, I; Koyanagi, A; Veronese, N; Soysal, PINAR; Yang, L; SOYSAL, PINAR
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    PublicationOpen Access
    Pet ownership and symptoms of depression: A prospective study of older adults.
    (2019-11-30) López-Sánchez, GF; Sharpley, C; Veronese, N; Smith, L; Bitsika, V; Demurtas, J; Celotto, S; Noventa, V; Soysal, PINAR; Grabovac, I; SOYSAL, PINAR
    Background:This paper aims to examine associations between pet ownership and symptoms of depression in alarge, population-based sample of older adults. Specifically, we tested whether: (i) people who report moredepressive symptoms are more likely to own a pet; (ii) pet ownership protects against an increase in depressivesymptoms over time; (iii) associations differ by symptom type.Methods:Data were drawn from the English Longitudinal Study of Ageing, a longitudinal panel study of men andwomen aged 50 and older (n= 7,617, 52.5% female). Pet ownership (dog/cat/other/none) was self-reported in2010/11. Depressive symptoms were assessed in 2010/11 and 2016/17 using the 8-item centre forEpidemiologic Studies Depression (CES-D) scale. We analysed total CES-D score and derived symptom subscales(depressed mood, anhedonia, somatic symptoms) in relation to pet ownership, adjusting for sociodemographicand health-related covariates.Results:A one-symptom increase in total CES-D score was associated with 7% increased odds of dog ownership(OR=1.07, 95% CI 1.03–1.11). Significant associations were observed between each subset of depressivesymptoms and dog ownership, with models run on z-scores showing a slightly stronger association for symptomsof depressed mood (OR=1.13, 95% CI 1.06–1.21) compared with anhedonia (OR=1.10, 95% CI 1.04–1.17) orsomatic symptoms (OR=1.10, 95% CI 1.03–1.18). Prospectively, no significant associations were found.Limitations:Self-reported data; small sample size for some pet categories. Conclusion:Amongst older adults in England, those with more depressive symptoms are more likely to own adog, but pet ownership is not significantly associated with change in depressive symptoms over time.