Person: ÇALIM, ÖMER FARUK
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Publication Metadata only Effect of Submucosal Mesna Application on Mucoperichondrial Elevation in Septoplasty(2017-01-01) Dogan, REMZİ; Yenigun, ALPER; Eren, SABRİ BAKİ; Ozturan, ORHAN; Goktas, Seda Sezen; Tugrul, Selahattin; Calim, Omer Faruk; EREN, SABRİ BAKİ; YENİGÜN, ALPER; TUĞRUL, SELAHATTİN; DOĞAN, REMZI; ÇALIM, ÖMER FARUK; ÖZTURAN, ORHANObjective: It was revealed that the thiol compound named mesna chemically softens the connective tissue with submucosal injection, and facilitates the endoscopic submucosal dissection. The authors aimed to investigate the effect of mesna injection on mucoperichondrial elevation during septoplasty operation. Methods: This study was planned as a patient-control study and performed. Fifty-six patients who had septoplasty operation were divided into 2 groups that are submucosal mesna (group 1) and submucosal saline (group 2) applied ones. In both groups, the measurement was initiated by a timer during the start of septal incision and elevation processes. After bilateral subperichondrial and subperiostal elevation were finished, timer was stopped and time was recorded. After that, mucosal integrity was reviewed and mucosal damage status was recorded. The difficulty of mucoperichondrial elevation for the surgeon was recorded for each patient. Results: Twenty-five (44.7%) of the patients who participated in our study were females while 31 (55.3%) were males. The average elevation periods were 201.4 +/- 74.3 seconds in group 1 and 260.2 +/- 84.1 seconds in group 2. In mesna applied patients, elevation period was statistically and significantly shorter (P = 0.009). Impairment in mucosal integrity was observed as 33.3% in group 1 and 58.8% in group 2. In mesna applied patients, significantly less impairment in mucosal integrity was observed (P = 0.031). The average mucoperichondrial elevation difficulty for the surgeon is observed as 4.83 +/- 2.47 in group 1 and 6.5 +/- 1.9 in group 2. Mesna applied patients were defined as significantly easier patients for the surgeon (P = 0.006). Conclusion: Submucosal mesna application is an approach that provides a convenient, fast, and effective mucoperichondrial elevation in septoplasty and protects the mucosal integrity.Publication Metadata only Temporal Scalp Thickness, Body Mass Index, and Suprafascial Placement of Receiver Coil of the Cochlear Implant.(2017-11-01) SENTURK, EROL; Ozturan, ORHAN; EREN, SABRİ BAKİ; AKSOY, FEYZA MÜBERRA; YENIGUN, A; ÇALıM, ÖMER FARUK; ÖZTURAN, ORHAN; YENİGÜN, ALPER; ŞENTÜRK, EROL; ÇALIM, ÖMER FARUK; AKSOY, FADLULLAH; EREN, SABRİ BAKİPublication Metadata only Evaluation of the eosinophil-to-lymphocyte ratio in pediatric patients with allergic rhinitis(2016-03-01) Yenigun, ALPER; Sezen, SEDA; Calim, Omer Faruk; Ozturan, ORHAN; YENİGÜN, ALPER; SEZEN GÖKTAŞ, SEDA; ÇALIM, ÖMER FARUK; ÖZTURAN, ORHANBackground: Allergic rhinitis is a type 1 hypersensitivity reaction of the nasal mucosa, the primary mediator of which is immunoglobulin E. Allergic rhinitis occurs in children and adolescents.Publication Metadata only Use of Mesna in the treatment of ossicular chain fixation related to tympanosclerosis; prospective, clinical study.(2020-01-01T00:00:00Z) Tugrul, S; Dogan, R; Vural, Ö; Ozturan, O; Yenigun, Alper; Calım, ÖF; EREN, SABRİ BAKİ; TUĞRUL, SELAHATTİN; YENİGÜN, ALPER; ÇALIM, ÖMER FARUK; ÖZTURAN, ORHANObjective: Mesna is a thiol compound effective in the connective tissue, which is used for its chemical dissector, mucolytic, mucosal damage preventive and antioxidant effects. The aim of this study was to investigate Mesna-s effects in easy dissection in type 4 tympanosclerosis cases and in the prevention of formation of new sclerotic plaques.Publication Metadata only The relationship between the tympanostomy tube extrusion time and viscosity.(2020-05-27T00:00:00Z) Tugrul, S; Calim, OF; Goktas, SS; Senturk, E; Ozturan, O; Dogan, R; Yenigun, Alper; DEĞİRMENCİ, NAZAN; TUĞRUL, SELAHATTİN; ŞENTÜRK, EROL; ÇALIM, ÖMER FARUK; YENİGÜN, ALPER; ÖZTURAN, ORHANPublication Metadata only Pediatric alopecia areata: evaluation of auditory and cochlear functions(2019-07-03T00:00:00Z) Soylu, Erkan; Yıldırım, Yavuz Selim; Bıyık Özkaya, Dilek; Yenigün, Alper; Özturan, Orhan; ÇALIM, ÖMER FARUK; YENİGÜN, ALPER; ÖZTURAN, ORHANIntroduction: The aim of this study was to evaluate the auditory and cochlear functions of alopecia areata (AA) in pediatric patients, which is an immune-mediated disease that occurs as a hair loss. Material & Methods: Patients aged between 5 and 17 years with AA at least 6 months were included in the study. In both groups, the mean values of pure tone audiogram (PTA) hearing thresholds and otoacoustic emission (OAE) measurements after otoscopic examination were compared. Otoacoustic emissions of the distortion product (DPOAE) 1, 2, 3, 4, 6 and 7 kHz frequencies were recorded. Results: The study included 54 volunteer children that were 22 healthy volunteer children and 32 with complaints of AA. When hearing averages and threshold values with PTA and OAE were examined, no hearing loss was observed in the speech frequencies (500-2000) in both groups (0%). In the 1st group mild hearing loss at PTA and OAE in 6 patients (20-40 db), and in high frequencies in both ears (8000-12000) in 2 patients (25%). In 24 patients, hearing loss were not observed in PTA and OAE (75%). In the second group, high frequency thresholds of PTA and OAE were observed normal (0%) (p < 0.05). Conclusions: It has been claimed that follicular melanocytes may be an important target in the autoimmune process of alopecia areata in current studies in the literature. AA can affect the hearing function by affecting the melanocytes in the inner ear. Therefore, the relationship between sensorineural hearing loss and an autoimmune disease, alopecia areata, can be established.