Goal: 03 - Sağlık ve Kaliteli Yaşam
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AMAÇ 3: SAĞLIKLI BİREYLER
Çocuk ölüm oranlarının azaltılması, anne sağlığının iyileştirilmesi, HIV/AIDS, sıtma ve diğer hastalıklar ile mücadelede büyük aşama kaydetmiş durumdayız. 1990 yılından bu yana, önlenebilir çocuk ölümlerinde dünya genelinde %50’yi aşan azalma olmuştur. Anne ölümleri de dünya genelinde %45 azalmıştır. 2000 ile 2013 arasında HIV/AIDS bulaşma oranı %30 azalmış, 6,2 milyonu aşkın insan sıtmadan kurtarılmıştır.
Bu ölümler; önleme ve tedavi, eğitim, aşı kampanyaları, cinsel ve üreme sağlığı hizmetleri vasıtasıyla önlenebilir. Sürdürülebilir Kalkınma Amaçları; AIDS, verem, sıtma ve diğer bulaşıcı hastalık salgınlarını 2030 yılına kadar ortadan kaldırmaya yönelik cesur bir taahhüttür. Amaç, herkesin genel sağlık hizmeti, güvenli ve erişilebilir ilaç ve aşıya kavuşmasını sağlamaktır. Aşı araştırma ve geliştirmelerinin desteklenmesi, bu sürecin vazgeçilmez bir parçasıdır.
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Publication Open Access Comparative Evaluation of Orthostatic Hypotension in Patients with Diabetic Nephropathy.(2021-07-20T00:00:00Z) Aytaş, Gamze; Elçioğlu, Ömer C; Kazancıoğlu, Rümeyza; Gürsu, Meltem; Artan, A Serra; Yabacı, Ayşegül; Soysal, PINAR; Bilgi, Kadir; Özçelik, Semra; KAZANCIOĞLU, RÜMEYZA; ELÇİOĞLU, ÖMER CELAL; GÜRSU, MELTEM; YABACI TAK, AYŞEGÜL; SOYSAL, PINAR; ÖZÇELİK, SEMRAIntroduction: Orthostatic hypotension (OH) affects 5-20% of the population. Our study investigates the presence of OH in diabetic nephropathy (DNP) patients and the factors affecting OH in comparison with nondiabetic chronic kidney disease (NDCKD) patients. Method: Patients presented to the nephrology clinic, and those who consented were included in the study. DNP was defined by kidney biopsy and/or clinical criteria. NDCKD patients of the same sex, age, and eGFR were matched to DNP patients. Demographic parameters and medications were obtained from the records. OH was determined by Mayo clinic criteria. The same researcher used an electronic device to measure blood pressure (BP). All samples were taken and analyzed the same day for biochemical and hematologic parameters and albuminuria. Results: 112 (51 F, 61 M, mean age: 62.56 ± 9.35 years) DNP and 94 (40 F, 54 M, mean age: 62.23 ± 10.08 years) NDCKD patients were included. There was no significant difference between DNP and NDCKD groups in terms of OH prevalence (70.5 vs. 61.7%, p = 0.181). Male patients had significantly higher OH prevalence than female patients (74.7 vs. 60.0%, p = 0.026). There was no significant difference in change in systolic BP between the groups (24.00 [10.00-32.00] mm Hg vs. 24.00 [13.75-30.25] mm Hg, p = 0.797), but the change in diastolic BP was significantly higher in the DNP group (8.00 [2.00-13.00] mm Hg vs. 6.00 [2.00-9.00] mm Hg, p = 0.025). In the DNP group, patients with OH had significantly higher uric acid levels than those without OH (7.18 ± 1.55 vs. 6.36 ± 1.65 mg/dL, p = 0.017). And, 73.7% of patients on calcium channel blockers developed OH (p = 0.015), and OH developed in 80.6% of 36 patients on alpha-blockers (p = 0.049). Conclusion: OH prevalence is very high in CKD, and etiology of CKD does not have a statistically significant effect on the frequency of OH, despite a difference that could be meaningful clinically. Therefore, patients with CKD are checked for OH, with or without concurrent diabetes mellitus. Evaluation of postural BP changes should be a part of nephrology practice.Publication Metadata only Tuberculosis in peritoneal dialysis patients in an endemic region.(2011-01-01T00:00:00Z) Gursu, MELTEM; TAYFUR, F; BESLER, M; KAPTANOGULLARI, O; KUCUK, M; AYDIN, Z; BASTURK, T; UZUN, S; KARADAG, S; TATLI, E; SUMNU, A; OZTURK, S; KAZANCIOGLU, RÜMEYZA; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZAPublication Open Access Determinants of mortality in a large group of hemodialysis patients hospitalized for COVID-19(2021-01-14T00:00:00Z) Turgutalp, Kenan; Ozturk, Savas; Arici, Mustafa; Eren, Necmi; Gorgulu, Numan; Islam, Mahmut; Uzun, Sami; Sakaci, Tamer; Aydin, Zeki; Sengul, Erkan; Demirelli, Bulent; Ayar, Yavuz; Altiparmak, Mehmet Riza; Sipahi, Savas; Mentes, Ilay Berke; Ozler, Tuba Elif; Oguz, Ebru Gok; Huddam, Bulent; Hur, Ender; Kazancioglu, Rümeyza; Gungor, Ozkan; Tokgoz, Bulent; Tonbul, Halil Zeki; Yildiz, Alaattin; Sezer, Siren; Odabas, Ali Riza; Ates, Kenan; KAZANCIOĞLU, RÜMEYZABackground Maintenance hemodialysis (MHD) patients are at increased risk for coronavirus disease 2019 (COVID-19). The aim of this study was to describe clinical, laboratory, and radiologic characteristics and determinants of mortality in a large group of MHD patients hospitalized for COVID-19. Methods This multicenter, retrospective, observational study collected data from 47 nephrology clinics in Turkey. Baseline clinical, laboratory and radiological characteristics, and COVID-19 treatments during hospitalization, need for intensive care and mechanical ventilation were recorded. The main study outcome was in-hospital mortality and the determinants were analyzed by Cox regression survival analysis. Results Of 567 MHD patients, 93 (16.3%) patients died, 134 (23.6%) patients admitted to intensive care unit (ICU) and 91 of the ones in ICU (67.9%) needed mechanical ventilation. Patients who died were older (median age, 66 [57–74] vs. 63 [52–71] years, p = 0.019), had more congestive heart failure (34.9% versus 20.7%, p = 0.004) and chronic obstructive pulmonary disease (23.6% versus 12.7%, p = 0.008) compared to the discharged patients. Most patients (89.6%) had radiological manifestations compatible with COVID-19 pulmonary involvement. Median platelet (166 × 103 per mm3 versus 192 × 103 per mm3, p = 0.011) and lymphocyte (800 per mm3 versus 1000 per mm3, p < 0.001) counts and albumin levels (median, 3.2 g/dl versus 3.5 g/dl, p = 0.001) on admission were lower in patients who died. Age (HR: 1.022 [95% CI, 1.003–1.041], p = 0.025), severe-critical disease clinical presentation at the time of diagnosis (HR: 6.223 [95% CI, 2.168–17.863], p < 0.001), presence of congestive heart failure (HR: 2.247 [95% CI, 1.228–4.111], p = 0.009), ferritin levels on admission (HR; 1.057 [95% CI, 1.006–1.111], p = 0.028), elevation of aspartate aminotransferase (AST) (HR; 3.909 [95% CI, 2.143–7.132], p < 0.001) and low platelet count (< 150 × 103 per mm3) during hospitalization (HR; 1.864 [95% CI, 1.025–3.390], p = 0.041) were risk factors for mortality. Conclusion Hospitalized MHD patients with COVID-19 had a high mortality rate. Older age, presence of heart failure, clinical severity of the disease at presentation, ferritin level on admission, decrease in platelet count and increase in AST level during hospitalization may be used to predict the mortality risk of these patients.Publication Metadata only Alteration of inflammation marker levels with alfa keto analogs in diabetic rats.(2022-09-01T00:00:00Z) Bildaci, Y D; Bulut, H; Elcioglu, O C; Gursu, M; Kazancioglu, Rümeyza; GÜRSU, MELTEM; KAZANCIOĞLU, RÜMEYZAPublication Metadata only Ritm Bozukluğu ile Acile Başvuran Kronik Hemodiyaliz Hastasında Aşırı Yüksek potasyum.(2017-10-10T00:00:00Z) ARTAN, AYŞE SERRA; GÜRSU, MELTEM; ELÇİOĞLU, ÖMER CELAL; DELİGÖZ BİLDACI, YELDA; SAYAN, CANAN; PEÇEN, MUSTAFA; GÜL, ELİF BUSE; KAZANCIOĞLU, RÜMEYZA; GÜRSU, MELTEM; ELÇİOĞLU, ÖMER CELAL; KAZANCIOĞLU, RÜMEYZAPublication Metadata only Diyabetik ayak enfeksiyonu için kullanılan tigesikline bağlı ciddi hipoglisemi:(2018-10-07) Kazancıoğlu, Rümeyza; Gürsu, Meltem; KAZANCIOĞLU, RÜMEYZA; GÜRSU, MELTEMPublication Metadata only Effect of ketoanalogues inflammation in diabetic nephropathic rats.(2018-05-27) DELİGÖZ BİLDACI, YELDA; GÜRSU, MELTEM; ELÇİOĞLU, ÖMER CELAL; KAZANCIOĞLU, RÜMEYZA; DELİGÖZ BİLDACI, YELDA; GÜRSU, MELTEM; ELÇİOĞLU, ÖMER CELAL; KAZANCIOĞLU, RÜMEYZAPublication Metadata only A new marker for endothelial function in peritoneal dialysis patients: Apelin Periton Diyalizi Hastalari{dotless}nda Yeni Bir Endotel Fonksiyonu Belirteci: Apelin(2013-04-23T00:00:00Z) Gürsu, MELTEM; Karadaǧ, Serhat; OZTURK, Savaş; Gürdal, Ahmet; BASINOGLU, Filiz; Aydın, Zeki; UZUN, Sami; SUMNU, Abdullah; Atalay, Eray; Oflaz, Hüseyin; Kazancioǧlu, RÜMEYZA; KAZANCIOĞLU, RÜMEYZAPublication Metadata only Ritm bozukluğu ile acile başvuran kronik hemodiyaliz hastasında aşırı yüksek potasyum(2017-10-22T00:00:00Z) KAZANCIOĞLU, RÜMEYZA; KAZANCIOĞLU, RÜMEYZAPublication Metadata only The effect of sleep apnea syndrome on the development of diabetic nephropathy in patients with type 2 diabetes(2012-10-01) Akkoyunlu, MUHAMMED EMİN; Kazancioglu, RÜMEYZA; Buyukaydin, BANU; OZCELIK, Hatice Kutbay; ERKOC, Reha; KART, Levent; BÜYÜKAYDIN, BANU; AKKOYUNLU, MUHAMMED EMİN; KAZANCIOĞLU, RÜMEYZAAims: Type 2 diabetes mellitus and obstructive sleep apnea syndrome (OSAS) are serious comorbidities. Effects of OSAS on diabetic microvascular complications are ongoing research subjects. We evaluated the incidence of OSAS in Type 2 diabetes mellitus patients with nephropathy and with no renal involvement.