Goal: 08 - İnsana Yakışır İş ve Ekonomik Büyüme
Loading...
Description
İnsana Yakışır İş ve Ekonomik Büyüme
İstikrarlı, kapsayıcı ve sürdürülebilir ekonomik büyümeyi, tam ve üretken istihdamı ve herkes için insana yakışır işleri desteklemek
15 results
Publication Search Results
Now showing 1 - 10 of 15
Publication Metadata only Palliative Care in High and Low Resource Countries(2021-01-01T00:00:00Z) KEBUDİ, Rejin; ÇAKIR, FATMA BETÜL; Silbermann, Michael; ÇAKIR, FATMA BETÜLPalliative Care (PC) is defined by the World Health Organization (WHO) as a support provided by multiple disciplines in order to improve the quality of life of both patients and their caregivers, throughout the disease course, from diagnosis to end- of-life. PC aims to prevent and treat symptoms and side effects of the disease and its treatment. PC is well developed in most high-income countries; however in most low-income settings, where approximately 80% of patients with cancer requiring PC care for advanced disease live, PC services are still uncommon. Health indicators monitoring global PC development are policy, education, use of medicines, service provision and professional activity. Globally, PC development may be categorized as Group 1 (no known hospice-PC activity), Group 2 (capacity-building activity), Groups 3a Isolated PC provided, 3b Generalized PC provided, 4a hospice-PC services at a stage of integration into regular service provision, and 4b hospice-PC services at a stage of advanced integration into regular service provision. Spirituality is an essential element of patient-centered PC. The use of Complementary and Traditional Medicine (CTM) in Middle Eastern countries is widespread. There are wide discrepancies in cancer care and PC in many regions of the world. The Individualized Care Planning and Coordination (ICPC) Model is designed to facilitate the advance care planning with continuity of all the measures like symptom control or emotional, social and spiritual care of both the patient and the family during the disease steps like relapse or end of life.Publication Metadata only Bir Sosyal Değişim Katalizörü Olarak Sosyal Girişimcilik(2021-12-01T00:00:00Z) Kati, Beyza Gökçin; Toker, Kerem; TOKER, KEREMBu çalışmanın amacı, sosyal girişimcilik kavramını incelemek, tartışmak ve uygulama örnekleri ile sosyal girişimcilik alanında farkındalık yaratmaktır. Bu amaçla, çalışmada ilk olarak literatür incelenmiş ve sosyal girişimcilik kavramının farklı anlamları tartışılmıştır. Ayrıca, sosyal girişimciliğin amacı, önemi, boyutları ve faaliyet alanları açıklanmıştır. Ardından, geleneksel girişimcilik ve sosyal girişimcilik arasında karşılaştırma yapılmıştır. Sosyal girişimciliğe yönelik yapılan eleştiriler, sosyal girişimcilik eğitimi ve toplumda oluşan sosyal etki incelenmiştir. Sonrasında ise, Türkiye’deki sosyal girişimcilik uygulamaları detaylı anlatım ve örneklerle açıklanmıştır. Elde edilen sonuçlar, Türkiye’deki sosyal girişimcilik faaliyetlerinin 2000 yılından sonra artış gösterdiğini fakat kavramın herkes tarafından bilinmediğini ve bir kavram karmaşası yaşandığını göstermektedir. Son olarak, günümüzde sosyal girişimcilik, işletmeler ve bireyler bazında desteklenmektedir. Yapılan projelerle birlikte sosyal girişimcilik alanı daha da gelişmekte ve başta gençler olmak üzere sosyal girişimciliğe yönelen girişimci sayısında artış görülmektedir.Publication Metadata only Anxiety symptoms among informal caregivers in 47 low- and middle-income countries: a cross-sectional analysis of community-based surveys.(2021-11-14T00:00:00Z) Smith, Lee; Shin, Jae Il; Oh, Hans; López Sánchez, Guillermo F; Underwood, Benjamin; Jacob, Louis; Veronese, Nicola; Soysal, PINAR; Butler, Laurie; Barnett, Yvonne; Tully, Mark A; Koyanagi, Ai; SOYSAL, PINARPublication Metadata only Copy-number variations in adult patients with chronic immune thrombocytopenia(2020-09-01T00:00:00Z) Yücesan, Emrah; Ng, Ozden Hatirnaz; Yalniz, Fevzi Firat; Yilmaz, Hulya; Salihoglu, Ayse; Sudutan, Tugce; Eşkazan, Ahmet Emre; Ongoren, Seniz; Baslar, Zafer; Soysal, Teoman; Ozbek, Ugur; Sayitoglu, Muge; Ar, M. Cem; YÜCESAN, EMRAHObjectives Immune thrombocytopenia (ITP) is an autoimmune disease with heterogeneous background. FCGR2C mutations were defined in one third of the patients but genetic players have not been fully elucidated yet. Although childhood ITP present as benign, ITP in adulthood is chronic disease with treatment challenges. This study aimed to focus on adult ITP patients using a whole genome genotyping that is valuable approach to identify the responsible genomic regions for the disease. Methods Herein 24 adult primary-refractory for ITP patients were evaluated using HumanCytoSNP12BeadChip,Illumina. Forty-six age and sex matched healthy individuals, and ptients awith nonhematological conditions were analyzed as controls. Identified CNV regions were verified by qRTPCR. T-cell receptor beta and delta (TCRB/TCRG) clonality were assessed by heteroduplex analysis in mosaic cases. Results Several CNV losses and gains were defined (losses:2q,7q,17q,19p, and gains: 1q,2p,3q,4q,7q,10q,12p,13q,14q,15q,17p,20q,21p,22q,Xp). Mosaic changes of different sizes (0.2-17.77Mb) were identified in five patients and three of them showed clonality. CNV regions that were unique to ITP patients were identified for the first time and among these genes, those related to immune regulation, and cellular trafficking were noteworthy. Conclusion: Identified CNV regions harbor several candidate genes, the functions of which might shed light on the pathogenesis of chronic ITP.Publication Metadata only Does Workplace Stress Affect Decision-Making Styles of Clinical Nurses? A Survey Study(2021-05-01T00:00:00Z) Denizsever, Selin; Ateş, Nimet; Seren, Arzu Kader Harmancı; ATEŞ, NİMETBackground: Clinical nurses must make accurate decisions to provide safe and qualified nursing care in hospitals where the working environment gets stressful each day. Aim: To determine the decision-making styles and workplace stress levels of clinical nurses and to investigate whether their stress levels affect the decision-making styles of them. Methodology: Descriptive and cross-sectional study. This study took place in a public university hospital in Istanbul in 2016. The sample consisted of 337 nurses. Data were collected by a questionnaire that consisted of a demographic data form, -Melbourne Decision Making Questionnaire I-II- and -Workplace Stress Scale.- Result: There was a positive correlation between the scores of the Melbourne Decision Making Questionnaire II and the Workplace Stress Scale. There were differences between the participants’ Melbourne Decision Making Questionnaire I-II scores according to their Workplace Stress Scale scores. Conclusion: Nurses’ workplace stress levels and their decision-making styles were significantly related to each other. Nurses who were exposed to high level of workplace stress had a low level of self-esteem (selfconfidence) and tended to make decisions in hyper-vigilance style. Keywords: clinical nursing, decision making, workplace stressPublication Metadata only Association of Myeloperoxidase Gene Polymorphism With Iron Deficiency Anemia in Turkish Children(2021-10-01T00:00:00Z) USTABAŞ KAHRAMAN, Feyza; ÇAKIR, FATMA BETÜL; BUHUR PİRİMOĞLU, MELTEM; TORUN, EMEL; Ergen, Hayriye Arzu; DOĞAN DEMİR, AYŞEGÜL; USTABAŞ KAHRAMAN, FEYZA; ÇAKIR, FATMA BETÜL; TORUN, EMEL; DOĞAN DEMİR, AYŞEGÜLThis study was performed to investigate the gene polymorphisms of the myeloperoxidase (MPO) enzyme and to determine whether MPO gene polymorphisms influence the response to iron therapy in pediatric patients with iron deficiency anemia (IDA). In this case-control study, 50 Turkish children with IDA and 50 healthy controls were enrolled. Three MPO gene alleles were selected for genotyping in the study: GG, AG, and AA. The relationships of alleles with IDA were analyzed and compared in patients and controls. Pretreatment and posttreatment laboratory parameters and gene polymorphisms were compared in the patient group. There was a significant difference between patients with IDA and controls regarding genotype frequencies of the AA, GG, and AG alleles (P=0.005). However, the AG allele was found to be associated with variations in hemoglobin, red blood cell, hematocrit, mean corpuscular volumes, and mean corpuscular Hb concentrations levels. The frequency of AA, GG, and AG alleles of the MPO gene was potentially associated with changes in iron metabolism and the AG allele led to variations in various hemogram parameters.Publication Metadata only Efficacy of standardized tracheostomy training with a simulation model for healthcare providers: A study by ISPAT team(2021-11-01T00:00:00Z) Uyan, Zeynep S.; Atag, Emine; Ergenekon, Almala P.; GÖKDEMİR, YASEMİN; Gokler, Ozan; AY, NADİYE PINAR; Ikizoglu, Nilay Bas; Cenk, Muruvvet; ERDEM ERALP, ELA; Sivrikaya, Ulufer; Girit, Saniye; ÇAKIR, Erkan; Kilic, Ayse A.; Yazan, Hakan; Oksay, Sinem Can; Hepkaya, Evrim; Kiyan, Gursu; Karadag, Bulent; Karakoc, Fazilet; Oktem, Sedat; ÇAKIR, ERKANIntroduction Tracheostomy care in children may be challenging, due to lack of knowledge of healthcare providers (HCPs). The aim of this study was to determine the level of knowledge of HCP who follow patients with tracheostomy and to increase this level with theoretical training and training in a simulation laboratory. Materials and Methods ISPAT (IStanbul PAediatric Tracheostomy), a multidisciplinary team for tracheostomy care was established and a training program was prepared. Participants were subjected to theoretical and practical pretests which evaluated their knowledge levels and skills for care, follow-up, and treatment of a patient with tracheostomy. After the theoretical and practical training given to the participants with a simulation model, theoretical and practical posttests were applied. Results Fifty-one HCP from nine tertiary pediatric clinics in Istanbul were enrolled in the training program. Only six (11.8%) of them had received standardized training programs previously. Regarding the theoretical tests, seven of the 33 questions were indicated as essential. The knowledge level of the participants based on the essential questions significantly increased after the training (p < 0.05 for all of the essential questions). The total number of correct answers and correct answers of three subheadings also significantly increased after the practical training (p < 0.001 for all). Ninety-five percent of the participants assessed the course as good or excellent in general. Conclusion Training in a simulation laboratory in combination with theoretical education can improve the knowledge and skills of the HCP enabling improved care of children with a tracheostomy.Publication Metadata only Dynamic Thiol/Disulphide Homeostasis a Promising New Marker in the Diagnosis of Acute Appendicitis in Children: A Case Control Study of Acute Appendicitis and Abdominal Pain(2022-03-01T00:00:00Z) Mirapoglu, Semih Lutfi; Guler, Eray Metin; BEKTAY, MUHAMMED YUNUS; KOÇYİĞİT, ABDÜRRAHİM; Vehbilzzettin, Fikret; BEKTAY, MUHAMMED YUNUS; KOÇYİĞİT, ABDÜRRAHİMObjectives: One of the most common emergency surgery in pediatric surgery is due to acute appendicitis (AA). The diagnosis of AA is usually made using with the clinical score using clinical signs, symptoms, and laboratory tests. But symptoms and signs are not always typical, and this situation put clinician in a compelling situation. The range of misdiagnosis of AA is between 28-57 % between 2-12 years old children. Thiol/Disulphide homeostasis is an important indicator of oxidative stress and inflammation. This study is aimed to evaluate and compare the feasibility of thiol/disulphide levels in pediatric patients with AA and abdominal pain (AP).Publication Metadata only Human paraoxonase-1 activity in children with acute bronchiolitis Akut bronşiolitli çocuklarda human paraoksonaz-1 aktivitesi(2020-01-01T00:00:00Z) ERENBERK, UFUK; Kahraman, Feyza Ustabaş; Özkaya, Emin; NURSOY, MUSTAFA ATİLLA; Demir, Ayşegül Doğan; TÜREL, Özden; ERENBERK, UFUK; ÖZKAYA, EMİN; NURSOY, MUSTAFA ATİLLA; TÜREL, ÖZDEN© 2020, Galenos. All rights reserved.INTRODUCTION: Human paraoxonase-1 (PON1) is one of the endogenous antioxidant molecules working against oxidative stress. We aimed to investigate serum PON1 activity in children with acute bronchiolitis. MATERIALS and METHODS: A total of 29 children aged between 3-21 months with acute bronchiolitis and 35 age-matched healthy controls were included in the study. Bronchiolitis patients were further classified as mild (65%) and moderate (35%). Paraoxonase and arylesterase activities of PON1 were compared between patients with acute bronchiolitis and the control group. RESULTS: Paraoxonase activity of children with acute bronchiolitis was lower than healthy controls but the difference was not significant (127.53 ± 64.17 U/L versus 153.95 ± 74.40 U/L) (p=0.13). Arylesterase activity was significantly decreased in children with mild and moderate bronchiolitis in comparison to the control group (142.43± 56.60 kU/L and 103.70± 26.03 kU/L versus 201.09± 57.26 kU/L) (p<0.001). CONCLUSIONS: Serum PON1 activity was lower in children with acute bronchiolitis compared to controls. Increasing antioxidant capacity may be an effective means of therapy in viral induced lung disease.Publication Metadata only Hastanede yatan çocuk hastalarda dermatoloji konsültasyonlarının değerlendirilmesi(2021-01-01T00:00:00Z) Uzuner, Selçuk; Ustabaş Kahraman, Feyza; Bahalı, Anıl Gülsel; Küçük, Özlem Su; UZUNER, SELÇUK; USTABAŞ KAHRAMAN, FEYZA; BAHALI, ANIL GÜLSELAmaç:Hastanede yatan hastalarda, dermatolojik şikâyetler sık görülebilmektedir. Yatışları sırasında, yeni dermatolojik lezyonlar gelişebileceği gibi daha önceden bilinen dermatolojik hastalıkları alevlenebilmektedir. Literatürde, çocuk hastaların yatışları sırasında istenen, dermatoloji konsültasyonlarını değerlendiren sınırlı sayıda çalışma vardır. Çalışmamızın amacı, hastanede yatan çocuk hastalarda dermatoloji konsültasyonlarını tanımlamaktır.Gereç ve Yöntemler:Pediatri servisinden, 4 yıl içinde dermatoloji kliniğine konsülte edilen toplam 137 hasta bu çalışmaya dâhil edilmiştir. Veriler geriye dönük olarak kayıtlardan elde edilmiştir.Bulgular:Konsültasyonlar genel pediatri servisinden istendi. Yatarak tedavi gören çocuk hastaların, en sık birincil tanısı akciğer hastalığıydı. Yüz otuz yedi hastada en sık görülen dermatolojik tanı, alerjik hastalık ve ardından deri enfeksiyonlarıydı. Dermatoloji tarafından tanıya yardımcı olmak için 28 hastaya deri biyopsisi yapıldı. Konsültasyon öncesinde, kliniğimiz ön tanısı ile konsültasyon sonrasında dermatoloji tanısı arasında uyum varlığının değerlendirilmesinde ise 32 hasta farklı tanı almıştı.Sonuç:Pediatristler, hasta izlemlerinde cilt lezyonlarıyla sık karşılaşmaktadır. Aynı zamanda dermatologların da hasta grubunun önemli bir kısmını çocuk hastalar oluşturmaktadır. Bu nedenle 2 kliniğin, dermatolojik şikâyeti olan çocuk hastalar söz konusu olduğunda, gerektiğinde iş birliği yapabilmeleri doğru bir yaklaşımdır. Pediatri ve dermatoloji klinikleri arasında, karşılıklı eğitime de katkı sağlayan konsültasyon muayeneleri, bu iş birliğine verilebilecek örneklerden biridir