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The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation

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The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation.pdf (682.3Kb)
Date
2018-11-01
Author
Ay, Nuray Kahraman
ENHOŞ, ASİM
AY, YASİN
Bakhshaliyev, Nijad
Ozdemir, Razaman
NADİR, AYDIN
KARAÇÖP, ERDEM
ÇELİKKALE, İLKE
ULUGANYAN, MAHMUT
Goktekin, Omer
Advisor
Type
Article
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Abstract
Background Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to examine the predictive role of fQRS morphology on long-term prognosis in patients undergoing TAVI due to severe aortic stenosis. Methods A total of 117 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study. Patients were assigned into two groups based on the presence (n = 36) or absence (n = 81) of fQRS. Predictors of long-term survival were estimated. Results In-hospital mortality was higher in fQRS group (5.5% vs. 1.2%, p = 0.0224). In the long-term, fQRS (OR: 3.06, 95% CI 1.29–7.27, p: 0.01), LVEF <50% (OR: 2.54, 95% CI 1.07–6.02, p: 0.03) and presence of atrial fibrillation (OR: 2.42, 95% CI 1.05–5.60, p: 0.03) emerged as significant independent predictors of short survival. Conclusion Presence of fQRS on ECG, an indirect indicator of myocardial fibrosis, seems to have the potential to be used as a prognostic marker after TAVI procedure. Large prospective studies are warranted.
Subject
Transcatheter aortic valve implantation (TAVI)
Aortic stenosis
Fragmented QRS (fQRS)
Myocardial fibrosis
Prognosis
URI
https://hdl.handle.net/20.500.12645/10722
https://doi.org/10.1016/j.jelectrocard.2018.07.015
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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS