Publication: The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation
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Date
2018-11-01
Authors
Ay, Nuray Kahraman
ENHOŞ, ASİM
AY, YASİN
Ozdemir, Razaman
NADİR, AYDIN
KARAÇÖP, ERDEM
ÇELİKKALE, İLKE
ULUGANYAN, MAHMUT
Goktekin, Omer
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Abstract
Background
Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to examine the predictive role of fQRS morphology on long-term prognosis in patients undergoing TAVI due to severe aortic stenosis.
Methods
A total of 117 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study. Patients were assigned into two groups based on the presence (n = 36) or absence (n = 81) of fQRS. Predictors of long-term survival were estimated.
Results
In-hospital mortality was higher in fQRS group (5.5% vs. 1.2%, p = 0.0224). In the long-term, fQRS (OR: 3.06, 95% CI 1.29–7.27, p: 0.01), LVEF <50% (OR: 2.54, 95% CI 1.07–6.02, p: 0.03) and presence of atrial fibrillation (OR: 2.42, 95% CI 1.05–5.60, p: 0.03) emerged as significant independent predictors of short survival.
Conclusion
Presence of fQRS on ECG, an indirect indicator of myocardial fibrosis, seems to have the potential to be used as a prognostic marker after TAVI procedure. Large prospective studies are warranted.
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Keywords
Transcatheter aortic valve implantation (TAVI), Aortic stenosis, Fragmented QRS (fQRS), Myocardial fibrosis, Prognosis
Citation
Ay N. K. , ENHOŞ A., AY Y., Bakhshaliyev N., NADİR A., KARAÇÖP E., ÇELİKKALE İ., ULUGANYAN M., Ozdemir R., Goktekin O., -The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation-, JOURNAL OF ELECTROCARDIOLOGY, cilt.51, ss.923-927, 2018