Research Project:
Experimental studies on the effect of antibiotics on the early development of Cicadellidae

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dc.contributorRafıqı, Abdul Matteen
dc.contributorPolo , Priscila Gomez
dc.date.accessioned2023-02-17T09:32:44Z
dc.date.available2023-02-17T09:32:44Z
dc.date.issued2019-11-01
dc.descriptionAntibiotics are substances commonly used against bacterial infections. There is increasing concern about the effects of antibiotics on the environment. The development of antibiotic-resistant strains of bacteria can disturb bacterial ecosystems and lead to serious health threats to humans. Moreover, the loss or imbalance of microbiota, called dysbiosis, causes several disorders in humans. Although a lot is known about the mode of action of antibiotics and their effect on population growth of the microbes within the organisms and within the environment, the effect of endosymbiont-loss on the developmental and organismal processes remain largely unknown. To address this we propose to study the insects of the family of Cicadellidae, commonly calledleafhoppers. These insects associate with two types of obligate bacterial endosymbionts. Previous studies have shown that loss of endosymbionts in leafhoppers causes patterning defects leading to posterior truncation of the embryo. We hypothesize that the endosymbionts in these insects interact with genes that have a role in development so that eggs from leafhoppers treated with antibiotics cannot develop properly. To test this hypothesis we aim to measure the effect of loss of endosymbionts on the expression of developmental genes that are involved in posterior formation. The research will help us to understand the effect of dysbiosis on gene regulatory network in Cicadellidae and offers new possiblitities to understand similar conditions in humans. Because antibiotics pose a major threat to the environment, this project has implications on environmental conservation and in search for eco-friendly pest and infectious disease vector management strategies.
dc.identifier9.2019/5
dc.identifier.urihttps://hdl.handle.net/20.500.12645/36397
dc.subjectSağlık Bilimleri
dc.subjectVeteriner Bilimleri
dc.subjectTarımsal Bilimler
dc.subjectZiraat
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectHealth Sciences
dc.subjectVeterinary Sciences
dc.subjectAgricultural Sciences
dc.subjectAgriculture
dc.subjectLife Sciences
dc.subjectNatural Sciences
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectKlinik Tıp (MED)
dc.subjectTemel Bilimler (SCI)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectBitki ve Hayvan Bilimleri
dc.subjectTarım Bilimleri
dc.subjectDoğa Bilimleri Genel
dc.subjectVETERİNERLİK BİLİMLERİ
dc.subjectÇOK DİSİPLİNLİ BİLİMLER
dc.subjectAgriculture & Environment Sciences (AGE)
dc.subjectClinical Medicine (MED)
dc.subjectNatural Sciences (SCI)
dc.subjectLife Sciences (LIFE)
dc.subjectPLANT & ANIMAL SCIENCE
dc.subjectAGRICULTURAL SCIENCES
dc.subjectNATURAL SCIENCES, GENERAL
dc.subjectVETERINARY SCIENCES
dc.subjectMULTIDISCIPLINARY SCIENCES
dc.subjectMultidisciplinary
dc.subjectVeterinary (miscellaneous)
dc.subjectGeneral Veterinary
dc.subjectEquine
dc.titleExperimental studies on the effect of antibiotics on the early development of Cicadellidae
dspace.entity.typeProject
local.avesis.id367361e4-e988-4e0c-ac51-5cf5f0366634
local.project.countryTürkiye
local.project.statusDevam Ediyor
local.project.typeYükseköğretim Kurumları Destekli Proje
project.endDate2021-09-20
project.startDate2019-11-01

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