Person: HACIOSMANOĞLU, EBRU
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Publication Green Synthesis Of Organic-Inorganic Hybrid Nanoflowers Using The Plant Extract Of Aloe Vera And Determination Of Their Bioactive(2021-11-05T00:00:00Z) Altınkaynak, Cevahir; Hacıosmanoğlu, Ebru; Ekremoğlu, Murat; Hacıoğlu, Mayram; Özdemir, Nalan; HACIOSMANOĞLU, EBRUPublication Impact of N‑Acetylcysteine and Antibiotics Against Single and Dual Species Bioflms of Pseudomonas aeruginosa and Achromobacter xylosoxidans(2022-11-01) Yılmaz F. N.; Hacıoğlu M.; Hacıosmanoğlu E.; HACIOSMANOĞLU, EBRUPublication 2. Effects of Quorum sensing molecules Combinations with Antimicrobial Agents on Candida albicans and Pseudomonas aeruginosa Single and Dual-species Biofilms co-culture on bronchial epithelial cells(2023-09-08) Hacıosmanoğlu E.; Yetke H. İ.; Yılmaz F. N.; Hacıoğlu M.; HACIOSMANOĞLU, EBRU; YETKE, HANDE İPEKPublication Yeni Sentezlenen Amino ve Tiyoantrakinon Moleküllerinin Akciğer Kanseri Hücre Hattı (A549) Üzerindeki Anti-Proliferatif Etkilerinin İncelenmesi(2021-10-07T00:00:00Z) Vagifli, Fidan; Onul, Nihal; Özkök, Funda; Hacıosmanoğlu, Ebru; Bulut, Şeyma; Varol, Başak; HACIOSMANOĞLU, EBRUPublication PLGA-Kurkumin Nano-formülasyonunun Kanser Hücrelerinde NF-kB Alt Birimleri Düzeyi Üzerindeki Etkisinin İncelenmesi(2020-12-16T00:00:00Z) Bulut, Şeyma; Obakan, Pınar; Babalı Balıbey, Fatmanur; Hacıosmanoğlu, Ebru; Bahadori, Fatemeh; BABALI BALIBEY, FATMANUR; HACIOSMANOĞLU, EBRU; BAHADORİ, FATEMEHPublication Tip 2 Diyabette Melatonin ve Luzindol Kullanımının Böbrek ve Karaciğer Dokularında İnflamatuvar Sitokinlere Etkisinin Araştırılması(2019-10-31T00:00:00Z) YAPIŞLAR, HANDE; HACIOSMANOĞLU, EBRU; SARIOĞLU, TÜRKAN; HACIOSMANOĞLU, EBRUPublication Intracellular trafficking of diphtheria toxin and its mutated form, CRM197, in the endocytic pathway.(2018-04-19T00:00:00Z) Edis, BO; Haciosmanoglu, EBRU; Varol, B; Bektas, M; HACIOSMANOĞLU, EBRUPublication Bir Bakışta Fizyoloji(2019-09-01T00:00:00Z) Hacıosmanoğlu, Ebru; HACIOSMANOĞLU, EBRUPublication A low direct electrical signal attenuates oxidative stress and inflammation in septic rats(2021-09-01T00:00:00Z) Üstünova, Savaş; Hacıosmanoğlu, Ebru; Bulut, Huri; Kılıç, Aysu; Hekimoğlu, Emine Rümeysa; Tunc, Serkan; Kaygusuz, İrem; Tunc, Sevil; Tunc, Gulcin Beyza; Meral, Ismail; ÜSTÜNOVA, SAVAŞ; HACIOSMANOĞLU, EBRU; ELİBOL, BİRSEN; KILIÇ, AYSU; HEKİMOĞLU, EMİNE RÜMEYSA; MERAL, İSMAİLElectrical stimulation is proposed to exert an antimicrobial effect according to studies performed using bacterial and cell cultures. Therefore, we investigated the effects of electrification on inflammation in septic rats. Twenty-eight male Wistar albino rats were divided into 4 groups: healthy control (C), electrified healthy (E), sepsis (S), and electrified sepsis (SE) groups. Staphylococcus aureus (1 x 109 colonies) in 1 ml of medium was intraperitoneally injected into rats to produce a sepsis model. The rats in the E and SE groups were exposed to a low direct electrical signal (300 Hz and 2.5 volts) for 40 min and 1 and 6 h after bacterial infection. Immediately after the second electrical signal application, blood and tissue samples of the heart, lung, and liver were collected. An antibacterial effect of a low direct electrical signal was observed in the blood of rats. The effects of electrical signals on ameliorating changes in the histological structure of tissues, blood pH, gases, viscosity and cell count, activities of some important enzymes, oxidative stress parameters, inflammation and tissue apoptosis were observed in the SE group compared to the S group. Low direct electrical signal application exerts antibacterial, antioxidant, anti-inflammatory and antiapoptotic effects on septic rats due to the induction of electrolysis in body fluids without producing any tissue damage.Publication Development of Novel Mitochondrial Fission Inhibitors Targeting Drp1-GTPase Interaction(2022-09-01) Dal Yöntem F.; Baday S.; Bulut Ş.; Ghaderkalankesh B.; Hacıosmanoğlu E.; Bektaş M.; Akçakaya H.; HACIOSMANOĞLU, EBRU