Person: TÜREL, ÖZDEN
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Publication Perfore apandisit: Etkenlerin ve enfeksiyon belirteçlerinin klinik iyileşme ve antibiyotik seçimine etkisi(2017-10-28) MIRAPOGLU, S. L.; AYDOĞDU, İBRAHİM; TÜREL, ÖZDEN; ÇAY, ALİ; GÜLTEPE, BİLGE; AYDOĞDU, İBRAHİM; TÜREL, ÖZDEN; ÇAY, ALI; SÜMBÜL, BİLGEPublication Are Growing Pains Related to Vitamin D Deficiency? Efficacy of Vitamin D Therapy for Resolution of Symptoms(2015-01-01) Vehapoglu, AYSEL; Turel, Ozden; TURKMEN, Serdar; INAL, Berrin Belcik; Aksoy, TURGUT; OZGURHAN, Gamze; ERSOY, Murat; VEHAPOĞLU TÜRKMEN, AYSEL; TÜREL, ÖZDEN; AKSOY, TURGUTObjectives: The aim of this study was to investigate the 25-hydroxyvitamin D [25(OH)D] status of children with growing pains and to evaluate the efficacy of vitamin D treatment on the resolution of pain symptoms. Subjects and Methods: One hundred and twenty children with growing pains were included in a prospective cohort study. Serum 25(OH)D and bone mineral levels were measured in all subjects at the time of enrollment. The pain intensity of those with vitamin D deficiency was measured using a pain visual analog scale (VAS). After a single oral dose of vitamin D, the pain intensity was remeasured by means of the VAS at 3 months. The 25(OH)D levels and VAS scores before and after oral vitamin D administration were compared by means of a paired Student-s t test. Results: In the 120 children with growing pains, vitamin D insufficiency was noted in 104 (86.6%). Following vitamin D supplementation, the mean 25(OH)D levels increased from 13.4 +/- 7.2 to 44.5 +/- 16.4 ng/ml, the mean pain VAS score decreased from 6.8 +/- 1.9 to 2.9 +/- 2.5 cm (a mean reduction of -3.8 +/- 2.1, p < 0.001) and the difference was statistically significant. Conclusion: Supplementation with oral vitamin D resulted in a significant reduction in pain intensity among these children with growing pains who had hypovitaminosis D. (C) 2015 S. Karger AG, BaselPublication Karaciğerim gitti gidiyor(2017-02-18) TÜREL Ö.; USTABAŞ KAHRAMAN F.; KIRMACI Ç.; KHALİF F.; DOĞAN DEMİR A.; BAL ÇERMİK B.; TÜREL, ÖZDEN; USTABAŞ KAHRAMAN, FEYZA; DOĞAN DEMİR, AYŞEGÜLPublication Multisystem inflammatory syndrome in children associated with COVID-19 in 101 cases from Turkey (Turk-MISC study)(2022-02-01T00:00:00Z) Yilmaz Ciftdogan, Dilek; Ekemen Keles, Yildiz; Karbuz, Adem; ÇETİN, BENHUR ŞİRVAN; Elmas Bozdemir, Sefika; KEPENEKLİ KADAYİFCİ, EDA; Metin Akcan, Ozge; Ozer, Arife; Erat, Tugba; Sutcu, Murat; Buyukcam, Ayse; BELET, NURŞEN; Erdeniz, Emine Hafize; Dalgic Karabulut, Nazan; Hancerli Torun, Selda; ÖNCEL, SELİM; ORBAK, Zerrin; TÜREL, Özden; GAYRETLİ AYDIN, ZEYNEP GÖKÇE; KILIÇ, ÖMER; Yahsi, Aysun; Kara Aksay, Ahu; Ergenc, Zeynep; Petmezci, Mey Talip; OFLAZ, MEHMET BURHAN; Sarikaya, Remzi; Otar Yener, Gulcin; Ozen, Seval; Gul, Doruk; ARSLAN, GAZİ; Kara, Soner Sertan; Demirkol, Demet; YAZICI ÖZKAYA, PINAR; YOZGAT, YILMAZ; Varan, Celal; Kara, Manolya; ARGA, GÜL; YAKUT, NURHAYAT; Kilic, Ahmet Osman; ÇAKICI, ÖZLEM; Kucuk, Mehmet; Kaba, Ozge; KARAOĞLU ASRAK, HATİCE; BURSAL DURAMAZ, BURCU; Dalkiran, Tahir; Berna Anil, Ayse; TURĞUT, MEHMET; KARAPINAR, BÜLENT; Somer, Ayper; ELMALI, FERHAN; DİNLEYİCİ, ENER ÇAĞRI; ÇİFTCİ, ERGİN; KARA, ATEŞ; TÜREL, ÖZDEN; YOZGAT, YILMAZ; BURSAL DURAMAZ, BURCUAim Multisystem inflammatory syndrome in children (MIS-C) may cause shock and even death in children. The aim of this study is to describe the clinical features, laboratory characteristics and outcome of children diagnosed with MIS-C in 25 different hospitals in Turkey. Methods The retrospective study was conducted between 8 April and 28 October 2020 in 25 different hospitals from 17 cities. Data were collected from patients- medical records using a standardised form. Clinical and laboratory characteristics and outcomes according to different age groups, gender and body mass index percentiles were compared using multivariate logistic regression analysis. Results The study comprised 101 patients, median age 7 years (interquartile range (IQR) 4.6-9.3); 51 (50.5%) were boys. Reverse-transcriptase polymerase chain reaction (PCR) assay was positive in 21/100 (21%) patients; 62/83 (74.6%) patients had positive serology for SARS-CoV-2. The predominant complaints were fever (100%), fatigue (n = 90, 89.1%), and gastrointestinal symptoms (n = 81, 80.2%). Serum C-reactive protein (in 101 patients, median 165 mg/L; range 112-228), erythrocyte sedimentation rate (73/84, median 53 mm/s; IQR 30-84) and procalcitonin levels (86/89, median 5 mu g/L; IQR 0.58-20.2) were elevated. Thirty-eight patients (37.6%) required admission to intensive care. Kawasaki disease (KD) was diagnosed in 70 (69.3%) patients, 40 of whom had classical KD. Most patients were treated with intravenous immunoglobulin (n = 92, 91%) and glucocorticoids (n = 59, 58.4%). Seven patients (6.9%) died. Conclusion The clinical spectrum of MIS-C is broad, but clinicians should consider MIS-C in the differential diagnosis when persistent fever, fatigue and gastrointestinal symptoms are prominent. Most patients diagnosed with MIS-C were previously healthy. Immunomodulatory treatment and supportive intensive care are important in the management of cases with MIS-C. Glucocorticoids and intravenous immunoglobulins are the most common immunomodulatory treatment options for MIS-C. Prompt diagnosis and prompt treatment are essential for optimal management.Publication Ventriculoperitoneal shunt infections and re-infections in children: a multicentre retrospective study(2018-01-01) Yakut, Nurhayat; Soysal, Ahmet; Kadayifci, Eda Kepenekli; DALGIC, Nazan; CIFTDOGAN, Dilek Yilmaz; Karaaslan, Ayse; Akkoc, Gulsen; Demir, Sevliya Ocal; CAGAN, Eren; CELIKBOYA, Ezgi; KANIK, Ali; Dagcinar, Adnan; YILMAZ, Adem; OZER, Fusun; CAMLAR, Mahmut; Turel, Ozden; Bakir, Mustafa; TÜREL, ÖZDENPurpose: Ventriculoperitoneal shunt (VPS) is the most common treatment modality for hydrocephalus. However, VPS infection is a common and serious complication with high rates of mortality and morbidity. The objective of this study was to investigate causative agents and the management of VPS infections and to identify risk factors for re-infection in children.Publication Bacteremia due to Achromobacter xylosoxidans in neonates: clinical features and outcome(2013-07-01T00:00:00Z) TÜREL, Özden; Kavuncuoglu, Sultan; Hosaf, Emine; Ozbek, Sibel; Aldemir, Esin; Uygur, Turkan; Hatipoglu, Nevin; Siraneci, Rengin; TÜREL, ÖZDENObjective: We report an outbreak of Achromobacter xylosoxidans at a neonatal intensive care unit. We aimed to present clinical, laboratory and treatment data of the patients.Publication Epidemiology of Sepsis in Neonates: Microbiological Profile and Antibiotic Susceptibility(2019-12-01T00:00:00Z) Aldemir, Esin; Kavuncuoglu, Sultan; TÜREL, Özden; TÜREL, ÖZDENObjective: Continuous surveillance is important to be informed on local epidemiology and cover organisms likely to cause sepsis in empirical therapy. We aimed to determine the characteristics of neonates with sepsis and etiological organisms in a single center.Publication Human Paraoxonase-1 Activity in Children with Acute Bronchiolitis(2020-03-01) ERENBERK U.; USTABAŞ KAHRAMAN F.; ÖZKAYA E.; NURSOY M. A.; DOĞAN DEMİR A.; TÜREL Ö.; ERENBERK, UFUK; USTABAŞ KAHRAMAN, FEYZA; NURSOY, MUSTAFA ATİLLA; DOĞAN DEMİR, AYŞEGÜL; TÜREL, ÖZDENINTRODUCTION: Human paraoxonase-1 (PON1) is one of the endogenous antioxidant molecules working against oxidative stress. We aimed to investigate serum PON1 activity in children with acute bronchiolitis.Publication Perforated appendicitis in children: antimicrobial susceptibility and antimicrobial stewardship(2018-09-01) TÜREL, ÖZDEN; MİRAPOĞLU, SEMİH LÜTFİ; GÜLTEPE, BİLGE; TÜREL, ÖZDEN; MİRAPOĞLU, SEMİH LÜTFİ; SÜMBÜL, BİLGEPublication Scar Formation and Tuberculin Skin Test Response After Bacillus Calmette-Guerin Vaccination: Does Prematurity or Low Birth Weight Have an Impact?(2017-04-01T00:00:00Z) Cebeci, Sinem Oral; Kavuncuoglu, Sultan; TÜREL, Özden; Aldemir, Esin Yildiz; Kazanci, Selcen Yaroglu; TÜREL, ÖZDENObjectives: The present studyaimed at evaluating factors affecting scar formation and tuberculin skin test (TST) response in Bacillus Calmette-Guerin (BCG) vaccinated infants.