Person: ÖZER, ÖMER FARUK
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ÖMER FARUK
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ÖZER
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Publication Metadata only Total antioxidant status and oxidative stress in recurrent aphthous stomatitis(2016-03-01) TUGRUL, Selahattin; Kocyigit, ABDÜRRAHİM; Dogan, REMZİ; Eren, SABRİ BAKİ; SENTURK, EROL; Ozturan, ORHAN; OZAR, Omer Faruk; KOÇYİĞİT, ABDÜRRAHİM; DOĞAN, REMZI; EREN, SABRİ BAKİ; ŞENTÜRK, EROL; ÖZTURAN, ORHAN; ÖZER, ÖMER FARUKBackgroundRecurrent aphthous stomatitis is an idiopathic, chronic, recurrent inflammatory disease of the oral mucosa. It is thought that oxidative stress caused by systemic inflammation plays a basic role in the etiopathogenesis of recurrent aphthous stomatitis. The aim of this study is to review oxidative status and DNA damage in recurrent aphthous stomatitis.Publication Metadata only Upper reference limits for serum thyroid stimulating hormone levels in Turkish children(2014-06-01) ARAL, H.; Ozer, O. F.; ONUR, H.; ÇİLİNGİRTÜRK, AHMET METE; AKYILDIZ, M.; Ozgen, I. T.; GUVENEN, GÜVENÇ; KACAN, P. A.; COMERT, S.; SERIN, E.; ÖZER, ÖMER FARUK; ÖZGEN, İLKER TOLGA; GÜVENEN, GÜVENÇPublication Metadata only The Diagnostic Value of SCUBE1 in Acute Appendicitis(2017-01-01) DURSUN, A.; METIN, HÜSEYİN; GULEN, BEDİA; SONMEZ, ERTAN; Ozer, O. F.; SÖNMEZ, ERTAN; GÜLEN, BEDİA; METİN, HÜSEYİN; ÖZER, ÖMER FARUKBackground: SCUBE1 has recently been studied as a diagnostic biomarker for acute coronary syndrome, ischemic stroke, and acute mesenteric ischemia. The aim of this study is to evaluate the value of SCUBE1 and routine parameters used in patients diagnosed with acute appendicitis.Publication Metadata only RELATIONSHIP BETWEEN RHEUMATOID ARTHRITIS DISEASE ACTIVITY AND MYELOPEROXIDASE AND CATALASE ACTIVITIES AND THIOL LEVELS(2016-01-01) Camli, AHMET ADİL; TAŞPINAR, ÖZGÜR; Aydin, TEOMAN; KEPEKÇİ, MÜGE; Ozer, O. F.; Keskin, YAŞAR; Selek, S.; Mutluer, A. S.; ÇAMLI, AHMET ADİL; AYDIN, TEOMAN; ÖZER, ÖMER FARUK; SELEK, ŞAHABETTİNThe aim of this study is to evaluate myeloperoxidase activity, catalase activity and thiol levels at early with rheumatoid arthritis patients. Blood taken from the patients was diagnosed with RA according to American Rheumatism Association ACR 2010 criteria, but not employed the medication of DMARD (Disease-modifying antirheumatic drugs) in order to examine the antioxidant parameters of myeloperoxidase activity, catalase activity and thiol levels. Twenty nine patients with early RA and 61 healthy controls were included in the study. Peripheral blood samples were used for all the assays. The average age of the patients was 39.91 +/- 13.32 and their average BMI was 28.56 +/- 4.15. Erytrocyte sedimentation rate (ESR) and C-reactive protein (CRP) values have been found significantly high levels in RA group when we compare with control group. Catalase activity and thiol levels which means antioxidant parameters, have been found significantly low levels according to control group. When the parameters of myeloperoxidase activity were compared to the control group, the values of control group were significantly high. Stronger response in patients with early RA suggests that antioxidant markers may be useful in evaluating the progression of RA as well as in elucidating the mechanisms of disease pathogenesis.Publication Metadata only ASSESSMENT OF PARAOXONASE AND ARYLESTERASE ANTIOXIDATIVE PARAMETERS IN RHEUMATIC DISEASES(2016-01-01) Keskin, YAŞAR; Aydin, TEOMAN; TAŞPINAR, ÖZGÜR; KEPEKÇİ, MÜGE; Ozer, O. F.; Selek, S.; Camli, AHMET ADİL; Mutluer, A. S.; KESKİN, YAŞAR; AYDIN, TEOMAN; ÖZER, ÖMER FARUK; SELEK, ŞAHABETTİN; ÇAMLI, AHMET ADİLThe aim of this study is to evaluate the patient stress markers which has the early stage rheumatoid arthritis (RA). Blood samples were collected from the patients diagnosed with rheumatoid arthritis according to American Rheumatism Association ACR 2010 criteria, but not employed the medication of DMARD (Disease-modifying antirheumatic drugs) in order to examine the stress parameters of total oxidant status, total antioxidant status, paraoxonase, paraoxonase NaCl, arylesterase concentration. Twenty nine patients diagnosed with early stage RA and 61 healthy control group included in the study. Peripheral blood samples were examined for all the assays. The average age of the patients was 39.91 +/- 13.32 and their average BMI was 28.56 +/- 4.15. ESR and CRP values have been found significantly high levels in RA group when we compare with control group. OSI values, which means oxidant parameters, have been found significantly high compared to the control group. When the parameters of arylesterase were compared to the control group, the values of control group were significantly high.Publication Metadata only Oxidative stress and phenotype frequencies of paraoxonase-1 in teratozoospermia.(2019-04-22) AKBULUT, H; Ozer, OF; GULER, ERAY METİN; CAGLAR, HİFA GÜLRU; GEVHER, FATİH; KOKTASOGLU, FATMANUR; SELEK, S; ÖZER, ÖMER FARUK; AKBULUT, HABİB; GÜLER, ERAY METİN; ÇAĞLAR, HİFA GÜLRU; GEVHER, FATİH; KÖKTAŞOĞLU, FATMANUR; SELEK, ŞAHABETTİNOxidative stress causes infertility in men by affecting especially sperm morphology. The aim of the study was to examine the frequencies of paraoxonase-1 (PON1) phenotypes and the serum PON1, arylesterase, total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index, catalase and thiol levels in teratozoospermic infertile men and normospermic fertile men. The study included 184 teratozoospermic infertile men and 72 normospermic fertile men. The double substrate method was employed to determine the phenotype distribution of PON1. The evaluation of sperm morphology was made in accordance with the Kruger-s criteria. TAS, catalase and thiol levels were determined to be significantly lower in teratozoospermic infertile men compared to normospermic fertile men. A significant change was not observed in the levels of TOS, PON1 and arylesterase. There was a positive correlation between catalase and thiol levels and sperm morphology. While there were significantly more teratozoospermic men with AA phenotypes compared to normospermic men, there were significantly more persons with AB and BB phenotypes in normospermic men than in teratozoospermic men. As far as we know, such a study was conducted for the first time and suggests that PON1 phenotypic distribution may play a significant role in sterile males because of impaired sperm morphology.Publication Metadata only Comparison of serum thiol-disulphide homeostasis and total antioxidant-oxidant levels between exudative age-related macular degeneration patients and healthy subjects(2017-10-01) Elbay, AHMET; Ozer, Omer Faruk; AKKAN, Julide Canan Umurhan; Celik, Ugur; KUTLUTURK, Isil; Koytak, Arif; OZDEMIR, Hakan; ELBAY, AHMET; ÖZER, ÖMER FARUK; KOYTAK, İBRAHİM ARİF; ÖZDEMİR, MEHMET HAKANThe purpose of the study was to calculate serum total oxidant status (TOS), total antioxidant status (TAS), and dynamic thiol-disulphide (T-D) homeostasis in patients with age-related macular degeneration (AMD), and compare the results with healthy individuals.Publication Metadata only The Diagnostic Value of SCUBE1 in Unstable Angina Pectoris Patients(2016-12-01) OZKAN, Abuzer; Sonmez, ERTAN; OZDEMIR, Serdar; Ozer, Omer Faruk; MUHARREM, Nasifov; Gulen, BEDİA; KESKIN, Muhammed; SÖNMEZ, ERTAN; ÖZER, ÖMER FARUK; GÜLEN, BEDİAAim: Signal peptide complement C1r/C1s, Uegf, and Bmp1-epidermal growth factor-like domain-containing protein 1 (SCUBE1) has been used in research as a biomarker in acute coronary syndrome (ACS). The aim of this study is to determine if SCUBE1 and routine laboratory parameters are effective in distinguishing the patients presenting with clinical symptoms of unstable angina pectoris (USAP) from the patients who have non-ST-segment elevated myocardial infarction (NSTEMI) and non-cardiac chest pain patients (NCCP).Publication Metadata only Total oxidant and antioxidant status and paraoxonase 1 levels of children with noncystic fibrosis bronchiectasis(2020-02-13T00:00:00Z) Gedik, AH; Çakir, Erkan; Vehapoğlu, Türkmen; Özer, ÖF; Kaygusuz, SB; ÇAKIR, ERKAN; VEHAPOĞLU TÜRKMEN, AYSEL; ÖZER, ÖMER FARUKPublication Metadata only Raftlin, presepsin levels and thiol-disulfide homeostasis in acute appendicitis: A pilot study(2018-11-01) KOÇYİĞİT, ABDÜRRAHİM; ERSOY, YELİZ EMİNE; SELEK, ŞAHBETTİN; SÜMBÜL, BİLGE; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; MERAL, İSMAİL; YİĞİT, MEHMET; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; MERAL, İSMAİL; SÜMBÜL, BİLGE; SELEK, ŞAHABETTİN; ERSOY, YELIZ EMINEObjective: To investigate some of the new inflammatory and oxidative stress markers in acute appendicitis.