Person: AYDOĞDU, İBRAHİM
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Publication Open Access Does ozone administration have a protective or therapeutic effect against radiotherapy-induced testicular injury?(2019-03-01) AYDOĞDU, İBRAHİM; İLBEY, YUSUF ÖZLEM; ÇOBAN, GANİME; EKİN, RAHMİ GÖKHAN; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALİ; KIZILTAN, HURİYE ŞENAY; EKİN, ZÜBEYDE YILDIRIM; SILAY, MESRUR SELÇUK; SEMERCİ, MEHMET BÜLENT; AYDOĞDU, İBRAHİM; ÇOBAN, GANİME; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALI; KIZILTAN, HURİYE ŞENAYObjective: We investigate the protective and therapeutic effects of ozone therapy (OT) in radiotherapy (RT)‑induced testicular damage. Methods: Thirty healthy adult male Wistar rats divided into five groups consisting of six animals each as follows: (1) Control (C), (2) RT, (3) OT, (4) OT + RT, and (5) RT + OT group. Histopathological findings, Johnsen scores, thiobarbituric acid‑reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) levels were evaluated. Results: RT caused a significant decrease in testicular weight and Johnsen score compared to the control group. In addition, TBARS level was significantly higher, whereas GSH, SOD, catalase, and GPx levels were significantly lower in the RT group when compared to the control group. Pre and postRT OT significantly increased GSH, SOD, catalase, and GPx levels and decreased TBARS level. Furthermore, testicular weight and Johnsen score were increased with OT. Conclusions: The present study showed that OT is protective and therapeutic in radiation‑induced testicular damage. OT may be beneficial to the patients who underwent RT.Publication Open Access Comparison of Laparoscopic and Conventional Cystotomy/Partial Cystectomy in Treatment of Liver Hydatidosis(2019-01-01) Bektasoglu, HÜSEYİN KAZIM; HASBAHCECI, Mustafa; Taşçı, Yunus; Aydogdu, Ibrahim; MALYA, FATMA ÜMİT; Kunduz, ENVER; Dolay, KEMAL; BEKTAŞOĞLU, HÜSEYİN KAZIM; AYDOĞDU, İBRAHİM; MALYA, FATMA ÜMİT; KUNDUZ, ENVER; DOLAY, KEMALIntroduction. Hydatidosis is a zoonotic infection and treatment is mandatory to avoid complications. Surgery remains the frst choice in the treatment especially for CE2-CE3b cysts. Open or laparoscopic approaches are available. However, comparative studies are limited. Materials and Methods. Data of patients who underwent cystotomy/partial cystectomy for liver hydatidosis between January 2012 and September 2016 (n=77) were evaluated retrospectively. Recurrent cases and the patients with previous hepatobiliary surgery were excluded. 23 patients were operated upon laparoscopically and named as Group 1. 48 patients operated conventionally named as Group 2. Demographics, cyst characteristics, operative time, length of hospital stay, recurrences, and surgery related complications were evaluated. Results. Groups were similar in terms of demographics, cyst characteristics, and operative time. Te length of hospital stay was 3.4 days in Group 1 and 4.7 days in Group 2 (p=0,007). Te mean follow-up period was 17.8 months and 21.7 months, respectively (p=0.170). Overall complication rates were similar in two groups (p=0.764). Tree conversion cases occurred (13%). One mortality was seen in Group 2. Four recurrences occurred in each group (17% versus 8.3%, respectively) (p=0.258). Conclusions. Laparoscopy is a safe and feasible approach for surgical treatment of liver hydatidosis. Recurrence may be prevented by selection of appropriate cases in which exposure of cysts does not pose an intraoperative difcultyPublication Open Access Investigation into the optimal prosthetic material for wound healing of abdominal wall defects(2018-02-01T00:00:00Z) Akcakaya, ADEM; Aydogdu, Ibrahim; ÇİTGEZ, Bulent; AKÇAKAYA, ADEM; AYDOĞDU, İBRAHİMThe purpose of this experimental study is to investigate and compare the effects of prosthetic materials used for wound healing of abdominal wall hernias. A total of 60 rats were divided into five equal groups: Group I, control subjected to laparotomy; group II, abdominal wall defect 3x2 cm+polypropylene (PP) mesh; group III, abdominal wall defect 3x2 cm+PP mesh+hyaluronate and carboxymethylcellulose (H-CMC; Seprafilm (R)); group IV, abdominal wall defect 3x2 cm+polytetrafluoroethylene (PTFE; Composix (TM)); and group V, abdominal wall defect 3x2 cm+polyethylene terephthalate (PET; Dacron (R)). A total of 14 days after the surgery, rats were sacrificed and the meshes with the surrounding tissue were extracted in block. The breaking strength of the mesh from the fascia was recorded. The healing tissue was examined with the index of histopathology and the hydroxyproline value was analyzed using the Switzer method. Both the breaking strength and histopathological index of the wound healing were significantly improved in groups II and III compared with that in groups IV and V (P<0.001). Hydroxyproline values were the highest in group I (P<0.001). There was also a statistically significant difference between groups II and IV, and group V and the other groups (P<0.001). The present findings demonstrated that PP mesh and PP mesh+H-CMC had a superior breaking strength and improved histopathologic indices compared with PTFE and PET. Furthermore, hydroxyproline values were the lowest in the PET group. In conclusion, wound healing was improved in the PP mesh group and the PP mesh+H-CMC group compared with the PTFE and PET groups according to the present study parameters.Publication Open Access Pure laparoscopic management of a giant ovarian cyst in an adolescent(2014-01-01) KILINCASLAN, Huseyin; CIPE, Gokhan; AYDOĞDU, İBRAHİM; SARAC, Fatma; TOPRAK, HÜSEYİN; ARI, Engin; AYDOĞDU, İBRAHİM; TOPRAK, HÜSEYİNBackground: The use of the laparoscopic approach versus open approach for the management of giant ovarian cysts is controversial. Exclusion of malignant conditions has critical importance in the laparoscopic management of these cases. However, in some cases, the possibility of malignancy and the ovarian origin of a cyst cannot be excluded during the preoperative period. Case Report: Herein we present the case of a 16-year-old girl with a giant ovarian cyst. The abdominal cavity was laparoscopically explored, and no signs suggestive of malignancy were encountered; the ovarian origin of the cyst was confirmed. A Veress needle was inserted percutaneously, and the cyst was drained and laparoscopically excised. No complications were encountered at follow-up visits 3 and 6 months after surgery. Conclusions: In addition to the well-known advantages of laparoscopic surgery (e.g., decreased postoperative pain, length of hospital stay, and wound infection), perfect cosmetic results are particularly important for young women. The pure laparoscopic management of giant ovarian cysts is safe and feasible.Publication Metadata only Transperitoneal laparoscopic heminephroureterectomy in the pediatric population: A single-centre experience using a sealing device(2018-09-01T00:00:00Z) Aydogdu, Ibrahim; SILAY, MESRUR SELÇUK; AYDOĞDU, İBRAHİMIntroduction: We sought to report the outcomes of transperitoneal laparoscopic heminephroureterectomy (LHNU) in a pediatric population and to describe the technical details of this minimally invasive surgery.Publication Open Access Traumatic rupture of solid pseudopapillary tumors of the pancreas in children: A case report.(2016-11-01) MIRAPOĞLU, SEMİH LÜTFİ; AYDOGDU, I; Gucin, ZÜHAL; UMUTOGLU, T; KILINCASLAN, H; MİRAPOĞLU, SEMİH LÜTFİ; AYDOĞDU, İBRAHİM; GÜCİN, ZÜHAL; YILMAZ, TEMEL FATİHSolid pseudopapillary tumor (SPT) of the pancreas is a pathological entity rarely encountered in children. Despite its malignant characteristics, SPT has a favorable clinical prognosis. This tumor is more frequently observed in females and is commonly localized in the tail and body of the pancreas. This is the case report of a 9-year-old female patient who presented with severe abdominal pain of sudden onset and vomiting following blunt abdominal trauma. Upon physical examination, abdominal distension, tenderness and abdominal guarding were detected. Abdominal magnetic resonance imaging revealed a mass sized 8×9×12 cm in the pancreas, with hemorrhagic-necrotic areas, and abundant intra-abdominal fluid. Intra-abdominal exploration confirmed the presence of an abundant amount of intraperitoneal hemorrhagic fluid. A mass was identified, originating from the body and the tail of the pancreas, adherent to the mesentery of the colon and the hilum of the spleen, which had ruptured in its inferolateral side. The tumor was extirpated together with the spleen and the involved parts of the pancreas. Histopathological examination demonstrated a solid pseudopapillary tumor of pancreatic origin. The patient's postoperative course was uneventful, clinically as well as metabolically.