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Now showing 1 - 10 of 69
  • PublicationMetadata only
    Comparison of uroflowmetry tests performed with a sensation of normal desire to void versus urgency and correlation of test results with IPSS
    (2020-09-01T00:00:00Z) Keskin, Mehmet Zeynel; Karaca, Erkin; UÇAR, MURAT; Ates, Erhan; Yucel, Cem; Ilbey, YUSUF ÖZLEM; İLBEY, YUSUF ÖZLEM
    Objective: The objective of this study was to evaluate the uroflowmetry test results performed for normal and urgent desire to void and their correlation with International Prostate Symptom Score (IPSS) values in adult male patients having lower urinary tract symptoms (LUTS) complaints.
  • PublicationMetadata only
    Rosiglitazone, peroxisome proliferator receptor-gamma agonist, ameliorates gentamicin-induced nephrotoxicity in rats
    (2010-09-01T00:00:00Z) Ozbek, Emin; İLBEY, YUSUF ÖZLEM; Simsek, Abdulmuttalip; ÇEKMEN, MUSTAFA BAKİ; Mete, Fatih; Somay, Adnan; İLBEY, YUSUF ÖZLEM
    Nephrotoxicity is a major complication of gentamicin (GEN), which is widely used in the treatment of severe gram-negative infections. Reactive oxygen spaces (ROS) are important mediators of gentamicin-induced nephrotoxicity. Peroxisome proliferator-activated receptors (PPARs) have different activities including antioxidant properties. This study was performed to investigate the protective role of PPAR-gamma agonist against GEN-induced nephrotoxicity. Male Wistar Albino rats were randomly divided into the following four groups, each of which consisted of six animals: (1) control; (2) intraperitoneally injected with GEN for 14 consecutive days (100 mg/kg/day); (3) treatment with rosiglitazone (RSG) via nasogastric gavage (10 mg/kg/daily for 14 days); (4) treatment with GEN + RSG combination for 14 day. Rats were decapitated on the 15th day and kidneys were removed. Urine was collected for every 24 h for the determination of daily urine volume. Urea, creatinine, Na+ and K+ levels were measured in blood. Malondialdehyde (MDA), reduced glutathion (GSH), and nitric oxide (NO) levels along with glutathione peroxidase (GSH-Px), catalase (CAT), and superoxide dismutase (SOD) activities were determined in the renal tissue. Changes in body weight were recorded. GEN treatment was found to cause nephrotoxicity as evidenced by elevation of serum urea and creatinine levels. Renal impairment was also assessed by the renal histology. The significant decrease in GSH and increases in MDA and NO levels as well as a decrease in GSH-Px, CAT, and SOD activities indicated that GEN-induced renal damage was mediated through oxidative reactions. On the other hand, RSG administration protected kidney tissue against GEN-induced and free radical-mediated oxidative renal damage in rats.
  • PublicationMetadata only
    Malignant mesothelioma of tunica vaginalis: Two extremely rare case reports
    (2021-06-01T00:00:00Z) Karabacakoglu, Burak; Kisa, Erdem; Ozbilen, Mert Hamza; Karademir, Baris; Yardim, Serdar; Celik, Orcun; Suelozgen, Tufan; Ilbey, YUSUF ÖZLEM; İLBEY, YUSUF ÖZLEM
    Introduction: Malignant mesothelioma (MM) of tunica vaginalis is a very rare tumor and it has a poor prognosis. It is not easy to diagnose the disease preoperatively because there is a lack of comprehensive studies and information about the disease. We would like to present our two cases with severe scrotal edema and hydrocele, which were debrided perioperatively due to scrotal necrosis, followed by radical inguinal orchiectomy and subsequently diagnosed as MM of tunica vaginalis.
  • PublicationMetadata only
    Prostatic adenocarcinoma with initial metastatic spread to the mandible
    (2015-09-01T00:00:00Z) Cakmak, Ozgur; Tarhan, Huseyin; Kucuk, Ulku; Ilbey, YUSUF ÖZLEM; İLBEY, YUSUF ÖZLEM
    Prostate cancer is one of the commonest types of malignancy in males. Although prostate cancer has a propensity to metastasize to the bone, metastasis to the mandible is rare. Because of their uncommon incidence, the diagnosis of mandibular metastasis, especially those originating from the prostate, may represent a challenge both for urologists and dentists. Here we present a case of prostatic adenocarcinoma with initial metastatic spread to the mandible.
  • PublicationMetadata only
    Our percutaneous nephrolitotomy experience in patients with horseshoe kidney
    (2015-01-01T00:00:00Z) Suelozgen, Tufan; Isoglu, Cemal Selcuk; Turk, Hakan; Yoldas, Mehmet; Ilbey, Ozlem Yusuf; Zorlu, Ferruh; İLBEY, YUSUF ÖZLEM
    Objectives: Horseshoe kidney is the most common renal congenital fusion anomaly. Kidney stone formation is more common in horseshoe kidneys and some of them requires surgical procedure. So we want to evaluate the results of PNL in patients with horseshoe kidney anomaly.
  • PublicationMetadata only
    The effect of hydronephrosis grade on stone-free rate in retrograde intrarenal stone surgery with flexible ureterorenoscopy.
    (2021-04-15T00:00:00Z) Ergani, Batuhan; Ozbilen, Mert Hamza; Yalcın, Mehmet Yigit; Boyacıoglu, Hayal; Ilbey, YUSUF ÖZLEM; İLBEY, YUSUF ÖZLEM
  • PublicationMetadata only
    Comparison of penile prosthesis types- complications: A retrospective analysis of single center
    (2020-12-01T00:00:00Z) Kisa, Erdem; Keskin, Mehmet Zeynel; Yucel, Cem; Ucar, Murat; Yalbuzdag, Okan; Ilbey, YUSUF ÖZLEM; İLBEY, YUSUF ÖZLEM
    Objectives: The aim of this study was to compare clinical outcomes and complication rates associated with semirigid (malleable) and inflatable penile prostheses (PPs) and investigate the factors that influence these complications.
  • PublicationMetadata only
    Early Experience with Laparoendoscopic single-site pyeloplasty in Children
    (2011-04-01T00:00:00Z) Tugcu, Volkan; Ilbey, YUSUF ÖZLEM; Polat, Hakan; Tasci, Ali Ihsan; İLBEY, YUSUF ÖZLEM
    Objective: To present our initial clinical experience with laparoendoscopic single-site surgery (LESS) for ureteropelvic junction obstruction (UPJO) in the pediatric age group.
  • PublicationMetadata only
    Pyrrolidine dithiocarbamate treatment prevents ethylene glycol-induced urolithiasis through inhibition of NF-kappaB and p38-MAPK signaling pathways in rat kidney.
    (2010-06-01T00:00:00Z) Ilbey, YUSUF ÖZLEM; Ozbek, Emin; Simşek, Abdulmuttalip; Cekmen, Mustafa; Somay, Adnan; Tasci, Ali Ihsan; İLBEY, YUSUF ÖZLEM
  • PublicationMetadata only
    A comparison of renal vascular control techniques during laparoscopic nephrectomy
    (2021-04-01T00:00:00Z) Koc, Gokhan; Ekin, Gokhan Rahmi; Ergani, Batuhan; Ilbey, YUSUF ÖZLEM; İLBEY, YUSUF ÖZLEM
    Background: We compared outcomes of en bloc stapler ligation of the renal hilum with separate Hem-o-lok polymer clip ligation of the renal vessels during laparoscopic nephrectomy (LN). Materials and Methods: Clinical data of patients who underwent LN for renal surgery from January 2009 to December 2015 were collected. Operation time, estimated blood loss, device malfunction rate, open conversion rate, complications and arteriovenous fistula (AVF) formation were evaluated. Results: En bloc stapler ligation and separate clip ligation were performed in 64 and 66 patients, respectively. The mean operative time was 106.8 +/- 20.8 min (range: 70-165) in the en bloc stapler ligation group compared with 112.5 +/- 24.1 min (range: 70-180) in the separate clip ligation group (P = 0.147). The mean estimated blood loss was 141.4 +/- 124.1 ml (range: 25-600) in the en bloc stapler ligation group compared with 147.6 +/- 112.4 ml (range: 25-450) in the separate clip ligation group (P = 0.767). The open conversion was required in 7/64 (10.9%) and 2/66 (3.0%) patients in the en bloc stapler ligation and separate clip ligation groups, respectively (P = 0.093). Stapler device malfunction occurred in 6 patients (9.3%). There were no statistically significant differences in overall complications (P = 0.726), minor (Grade 1-2) complications (P = 0.698) and major (Grade 3-5) complications (P = 0.716). No patient was diagnosed with AVF formation during overall median 33-month (interquartile range: 30, range: 24-96) follow-up. Conclusions: En bloc stapler ligation of the renal hilum during nephrectomy is an effective and safe technique. Although there is no reported AVF formation with en bloc stapler ligation of the renal hilum, longer follow-up is necessary.