Person: RAFIQI, ABDUL MATTEEN
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Publication Metadata only Eco-Evo-Devo: The Time Has Come(2014-01-01T00:00:00Z) Abouheif, Ehab; Fave, Marie-Julie; Ibarraran-Viniegra, Ana Sofia; Lesoway, Maryna P.; Rafiqi, ABDUL MATTEEN; Rajakumar, Rajendhran; RAFIQI, ABDUL MATTEENThe major goal of ecological evolutionary developmental biology, also known as -eco-evo-devo,- is to uncover the rules that underlie the interactions between an organism-s environment, genes, and development and to incorporate these rules into evolutionary theory. In this chapter, we discuss some key and emerging concepts within eco-evo-devo. These concepts show that the environment is a source and inducer of genotypic and phenotypic variation at multiple levels of biological organization, while development acts as a regulator that can mask, release, or create new combinations of variation. Natural selection can subsequently fix this variation, giving rise to novel phenotypes. Combining the approaches of eco-evo-devo and ecological genomics will mutually enrich these fields in a way that will not only enhance our understanding of evolution, but also of the genetic mechanisms underlying the responses of organisms to their natural environments.Publication Metadata only Hox gene function in the development of ant(2022-10-18) Çolak B.; Rafıqı A. M.; AL, BİRGÜL ÇOLAK; RAFIQI, ABDUL MATTEENPublication Metadata only Role of Osmotin in Strawberry Improvement(2012-10-01T00:00:00Z) Husaini, Amjad M.; Rafiqi, ABDUL MATTEEN; RAFIQI, ABDUL MATTEENIn nature, plants are often exposed to multiple biotic and abiotic stresses, severely affecting their growth and development and reducing their productivity. Future predicted adverse climatic changes might threaten the very sustainability of crop production worldwide. Various approaches ought to be explored to deal with the challenges of sustained crop production under such conditions. In this review, we explore the potential of osmotin, a stress-responsive multifunctional pathogenesis-related (PR)-5c protein from tobacco, in improving adaptability of crop plants to climatic changes. As osmotin plays an important role in salt and drought tolerance as well as in cold tolerance and in protecting plants against some fungal pathogens, the relevance of osmotin in improving tolerance to abiotic and biotic stresses in strawberry, a salt-sensitive plant that is also susceptible to several fungal pathogens, is presented herein.Publication Metadata only Hox gene function in the evolution of body plan in Camponotus floridanus(2022-06-01) Çolak B.; Rafıqı A. M.; AL, BİRGÜL ÇOLAK; RAFIQI, ABDUL MATTEENPublication Metadata only Analysis of Dorsoventral Patterning of Camponotus floridanus(2022-05-31) Milat N. S.; Rafıqı A. M.; MİLAT, NİHAN SULTAN; RAFIQI, ABDUL MATTEENHighly conserved gene regulatory networks are responsible for pattern formation in development. In case of insects that host cellular endosymbionts, challenges are faced for understanding pattern formation because of the interactions between the endosymbiont and intercellular signals of the host developmental gene regulatory network. Studying how these networks are operated in the presence of endosymbionts is critical for understanding of the process of endosymbiosis at the organismal level as well as the evolution of developmental systems.We characterized Dorsal-Ventral (DV) patterning system of the ant, Camponotus floridanus. Since DV patterning depends heavily on Bone Morphogenetic Protein Signaling in many insects, we used molecular techniques such as gene cloning, in situ hybridization, and RNA interference to examine the expression and function of developmental genes that are particularly involved in Bone Morphogenetic Protein Signaling.Here we show the expression and function of core BMP signaling components for DV patterning of ant C. floridanus.Publication Metadata only Megaselia abdita: cuticle preparation from injected embryos.(2011-04-01T00:00:00Z) Rafiqi, ABDUL MATTEEN; Lemke, Steffen; Schmidt-Ott, Urs; RAFIQI, ABDUL MATTEENPublication Metadata only The scuttle fly Megaselia abdita (Phoridae): a link between Drosophila and Mosquito development.(2011-04-01T00:00:00Z) Rafiqi, ABDUL MATTEEN; Lemke, Steffen; Schmidt-Ott, Urs; RAFIQI, ABDUL MATTEENPublication Metadata only BMP-dependent serosa and amnion specification in the scuttle fly Megaselia abdita(2012-09-15T00:00:00Z) Rafiqi, ABDUL MATTEEN; Park, Chee-Hyurng; Kwan, Chun Wai; Lemke, Steffen; Schmidt-Ott, Urs; RAFIQI, ABDUL MATTEENBone morphogenetic protein (BMP) signaling is an essential factor in dorsoventral patterning of animal embryos but how BMP signaling evolved with fundamental changes in dorsoventral tissue differentiation is unclear. Flies experienced an evolutionary reduction of extra-embryonic tissue types from two (amniotic and serosal tissue) to one (amnionserosal tissue). BMP-dependent amnioserosa specification has been studied in Drosophila melanogaster. However, the mechanisms of serosal and amniotic tissue specification in less diverged flies remain unknown. To better understand potential evolutionary links between BMP signaling and extra-embryonic tissue specification, we examined the activity profile and function of BMP signaling in serosa and amnion patterning of the scuttle fly Megaselia abdita (Phoridae) and compared the BMP activity profiles between M. abdita and D. melanogaster. In blastoderm embryos of both species, BMP activity peaked at the dorsal midline. However, at the beginning of gastrulation, peak BMP activity in M. abdita shifted towards prospective amnion tissue. This transition correlated with the first signs of amnion differentiation laterally adjacent to the serosa anlage. Marker-assisted analysis of six BMP signaling components (dpp, gbb, scw, tkv, sax, sog) by RNA interference revealed that both serosa and amnion specification of M. abdita are dependent on BMP activity. Conversely, BMP gain-of-function experiments caused sharpened expression boundaries of extra-embryonic target genes indicative of positive feedback. We propose that changes in the BMP activity profile at the beginning of gastrulation might have contributed to the reduction of extra-embryonic tissue types during the radiation of cyclorrhaphan flies.Publication Metadata only Taxonomic classification analysis of human gut microbiota using Kraken 2(2021-07-29T00:00:00Z) MİLAT, NİHAN SULTAN; Çelik, Muhammet; RAFIQI, ABDUL MATTEEN; MİLAT, NİHAN SULTAN; RAFIQI, ABDUL MATTEENPublication Metadata only Investigation of the effect of different chelation solutions on penetration of resin‐based and bioceramic sealers with a novel method(2021-01-01T00:00:00Z) Alim, Betül Aycan; Şentürk , Hilal; Kotan, Gözde; Güneşer, Mehmet Burak; Dinçer, Asiye Nur; Rafıqı, Abdul Matteen; UYSAL, BETÜL AYCAN; KOTAN, GÖZDE; GÜNEŞER, MEHMET BURAK; DİNÇER, ASİYE NUR; RAFIQI, ABDUL MATTEEN
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