Person: YILDIRIM, YAVUZ SELİM
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Publication Open Access Otoacoustic Emission Responses of the Cochlea to Acute and Total Ischemia(2013-12-01) Yildirim, YAVUZ SELİM; AKSOY, Fadlullah; Ozturan, ORHAN; VEYSELLER, Bayram; DEMIRHAN, Hasan; YILDIRIM, YAVUZ SELİM; AKSOY, FADLULLAH; ÖZTURAN, ORHANIn the present experimental study, we sought to monitor distortion product otoacoustic emissions (DPOAEs) as an indicator of cochlear function, after sudden, total, and irreversible interruption of cochlear blood flow, to provide information on the time course of cochlear response to ischemia. Twenty rats with normal hearing function were included. Complete and abrupt ischemia was provided by decapitation. DPOAEs at 3–8 kHz frequencies were recorded at baseline and exactly every consecutive minute after decapitation, until emissions in all frequencies disappeared completely. Mean DPOAE values decreased significantly and progressively after decapitation for all frequencies. The mean duration of emissions was 8.20 ± 1.96 min (minimum 3 min, maximum 11 min). The longest durations of DPOAEs were observed with 4 and 5 kHz frequencies, and 3 and 6 kHz had the shortest durations. The outer hair cells exposed to acute ischemia seem to exhibit a rapid functional loss; thus, cautious handling of the cochlear vasculature and surrounding structures is necessary in surgical interventions. Additionally, our results provide some idea of the normal tolerance range of the cochlea to ischemia, which could be useful for future studiesPublication Open Access Effects of Intranasal Phototherapy on Nasal Microbial Flora in Patients with Allergic Rhinitis(2013-09-01T00:00:00Z) YILDIRIM, YAVUZ SELİM; Apuhan, Tayfun; Kocoglu, Esra; YILDIRIM, YAVUZ SELİMThe objective of this study was to investigate the effect of intranasal phototherapy on nasal microbial flora in patients with allergic rhinitis.Publication Open Access Olfactory Dysfunction and Olfactory Bulb Volume Reduction in Patients with Leprosy(2012-09-01) VEYSELLER, Bayram; AKSOY, Fadlullah; Yildirim, YAVUZ SELİM; ACIKALIN, R. Murat; GURBUZ, Defne; Ozturan, ORHAN; AKSOY, FADLULLAH; YILDIRIM, YAVUZ SELİM; ÖZTURAN, ORHANTo ascertain the level and rate of olfactory dysfunction in patients with leprosy and to determine whether olfactory bulb volume is affected by the pathophysiology. Olfactory bulb (OB) volume, measured using magnetic resonance imaging (MRI), was compared in 15 patients with leprosy and 15 healthy controls. All of the participants were evaluated using a detailed history to identify the probable causes of the smell dysfunction. Those who had a disease other than leprosy that may have caused the smell dysfunction were excluded from the study. OB volumes were calculated by manually tracing the OB on coronal sections. Orthonasal olfaction testing was used to assess smell function. The orthonasal olfaction testing indicated that all patients with leprosy were anosmic or severely hyposmic. The smell function test indicated that the OB volume of the patient group was significantly lower than that of the control group. No within-group difference was detected between right and left OB volume in either group. The patients in the leprosy group were severely hyposmic or anosmic and their olfactory bulb volume was significantly lower than that of the control group. To our knowledge, this study is the first to show a reduction in olfactory bulb volume among leprosy patients.Publication Open Access Is Transnasal Endoscopic Examination Necessary Before and After Adenoidectomy?(2014-01-01) Yildirim, YAVUZ SELİM; Apuhan, Tayfun; AKSOY, Fadlullah; VEYSELLER, Bayram; ÖZTURAN, ORHAN; YILDIRIM, YAVUZ SELİM; AKSOY, FADLULLAH; ÖZTURAN, ORHANThe present study aimed to investigate the amount of residual adenoid tissue following the conventional adenoidectomy as compared with preoperative values. A total of 32 girls and 44 boys (range, 3–15 years) in whom adenoidectomy procedure was planned were included in the study. Adenoid tissue sizes before adenoidectomy and residual tissue sizes after conventional curettage adenoidectomy were measured by transnasal endoscopic examination and were recorded. Adenoid tissue size before and after adenoidectomy was compared. The mean age of the patients was 7.7 years (range, 3–15 years). Before adenoidectomy grade 4 adenoid tissue was noted in 43.4% (n = 33), grade 3 was noted in 28.9% (n = 22), grade 2 was noted in 25% (n = 19), and grade 1 was noted in 2.6% (n = 2) of the patients. Following adenoidectomy, no significant difference was noted with respect to residual adenoid tissue sizes of grade 4 and grade 3 patients (P = 0.75, P = 0.76). Transnasal endoscopic examination is suggested to be the most appropriate method to assess the amount of residual adenoid tissue after conventional curettage adenoidectomy. The residual adenoid tissue with the help of a microdebrider in case of a large residual adenoid tissue located in the choana are necessary for complete adenoidectomyPublication Open Access Concha bullosa Reply(2013-07-01T00:00:00Z) Yildirim, Yavuz Selim; YILDIRIM, YAVUZ SELİMPublication Open Access Are There Any Systemic Effects of the Intratympanic Administration of Dexamethasone?(2018-07-01T00:00:00Z) Senturk, Erol; Tugrul, Selahattin; Yildirim, Yavuz Selim; DOĞAN, Remzi; EREN, SABRİ BAKİ; ÖZTURAN, ORHAN; ŞENTÜRK, EROL; YILDIRIM, YAVUZ SELİM; DOĞAN, REMZI; EREN, SABRİ BAKİ; ÖZTURAN, ORHANObjective: Systemic absorption of steroids is reasonable because of the lipophilic nature of steroids and high vascularity of the middle ear mucosa. To date, however, of the clinical trials designed to investigate this subject, to the best of our knowledge, none has been based on objective methods. This study aims to demonstrate whether the intratympanic administration of dexamethasone has any systemic effects.