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KAHRAMAN AY, NURAY

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NURAY
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KAHRAMAN AY
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    Swiss Cheese-Like Atrial Septal Defect Detected by Three-Dimensional Echocardiography
    (2015-07-01T00:00:00Z) Vatankulu, Mehmet A.; Jafarov, Parviz; KAHRAMAN AY, Nuray; KAHRAMAN AY, NURAY
    Mini-Abstract A 33-year-old female presented to the outpatient clinic with progressive exertional dyspnea. Transthoracic echocardiography revealed enlarged right heart chambers with left-to-right shunting. Two-dimensional transesophageal echocardiography confirmed these findings and showed three defects on interatrial septum. Real time three-dimensional transesophageal echocardiography was performed to better visualize the anatomy of the interatrial septum. Reconstruction of the three-dimensional images revealed multiple defects of interatrial septum like a Swiss cheese. The patient underwent surgical closure of the atrial septal defect.
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    -Mitral klip vakasında, transseptal ponksiyon sırasında aortik iyatrojenik perforasyonun, amplatzer ductal occluder ile başarılı kapatılması-
    (2019-04-28T00:00:00Z) ENHOŞ, ASİM; KAHRAMAN AY, NURAY; ULUGANYAN, MAHMUT; BAKSHALİYEV, NİJAD; YAMAÇ, AYLİN HATİCE; ÇELİKKALE, İLKE; İSMAİLOĞLU, ZİYA; BACAKSIZ, AHMET; ÖZDEMİR, RAMAZAN; ENHOŞ, ASIM; KAHRAMAN AY, NURAY; ULUGANYAN, MAHMUT; YAMAÇ, AYLİN HATİCE; ÇELİKKALE, İLKE; BACAKSIZ, AHMET; ÖZDEMİR, RAMAZAN
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    Impact of age on long term survival following transcatheter aortic valve implantation
    (2019-01-01T00:00:00Z) KAHRAMAN AY, Nuray; KAHRAMAN AY, NURAY
    Objective To compare the long-term survival following transcatheter aortic valve implantation (TAVI) in an octogenarian population with that in a younger population. Methods This retrospective study included 274 patients that underwent TAVI for severe symptomatic aortic stenosis. The study group was divided into two age groups, as those with an age >= 80 years (octogenarians, n = 132), and age < 80 (younger patients, n = 142). The two groups were compared in terms of clinical outcomes and survival. In addition, significant predictors of survival were estimated. Results Non-cardiac mortality (during follow-up) (21.9% vs. 10.5%, P = 0.01) and in-hospital stroke (8.3% vs. 2.8%, P = 0.01) were more common among octogenarians. The two groups did not differ in terms of mean survival (41.0 +/- 2.1 vs. 38.2 +/- 2.2 months, respectively, P = 0.18). Multivariate analysis identified left ventricular ejection fraction < 35% (OR: 2.17, 95% CI: 1.17-4.03; P = 0.01), preoperative of moderate to severe mitral insufficiency (OR: 1.88, 95% CI: 1.15-3.06; P = 0.01), postoperative major and life-threating bleeding (OR: 2.49, 95% CI: 1.05-5.89; P = 0.03), and in-hospital stroke (OR: 2.29, 95% CI: 1.04-5.04; P = 0.03) as potential predictors of poor survival. Conclusions In this study, similarly favorable survival outcomes were achieved in the elderly population as in younger patients, despite the presence of comorbid conditions. A consideration should be given to non-surgical management of severe aortic stenosis with the TAVI procedure in elderly patients, in the absence of co-existent conditions associated with shortened life expectancy.
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    Koroner arter baypas cerrahisi sonrası venöz tromboza bağlı pulmoner emboli
    (2012-10-01T00:00:00Z) KARA, İBRAHİM; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; Yıldırım, Tekin; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY
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    PublicationOpen Access
    The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation
    (2018-11-01) Ay, Nuray Kahraman; ENHOŞ, ASİM; AY, YASİN; Ozdemir, Razaman; NADİR, AYDIN; KARAÇÖP, ERDEM; ÇELİKKALE, İLKE; ULUGANYAN, MAHMUT; Goktekin, Omer; KAHRAMAN AY, NURAY; ENHOŞ, ASIM; AY, YASİN; BAKHSALIYEV, NIJAD; NADİR, AYDIN; KARAÇÖP, ERDEM; ÇELİKKALE, İLKE; ULUGANYAN, MAHMUT; ÖZDEMİR, RAMAZAN
    Background Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to examine the predictive role of fQRS morphology on long-term prognosis in patients undergoing TAVI due to severe aortic stenosis. Methods A total of 117 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study. Patients were assigned into two groups based on the presence (n = 36) or absence (n = 81) of fQRS. Predictors of long-term survival were estimated. Results In-hospital mortality was higher in fQRS group (5.5% vs. 1.2%, p = 0.0224). In the long-term, fQRS (OR: 3.06, 95% CI 1.29–7.27, p: 0.01), LVEF <50% (OR: 2.54, 95% CI 1.07–6.02, p: 0.03) and presence of atrial fibrillation (OR: 2.42, 95% CI 1.05–5.60, p: 0.03) emerged as significant independent predictors of short survival. Conclusion Presence of fQRS on ECG, an indirect indicator of myocardial fibrosis, seems to have the potential to be used as a prognostic marker after TAVI procedure. Large prospective studies are warranted.
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    A rare complication of pre-Eisenmenger patent ductus arteriosus: Pulmonary artery dissection
    (2013-01-01T00:00:00Z) AY, YASİN; KAHRAMAN AY, Nuray; AYDIN, CEMALETTİN; KARA, İBRAHİM; ZEYBEK, RAHMİ; AY, YASİN; KAHRAMAN AY, NURAY; AYDIN, CEMALETTİN; ZEYBEK, RAHMİ
    INTRODUCTION: Pulmonary artery dissection associated with patent ductus arteriosus is usually seen in patients with pulmonary hypertension and Eisenmenger-s syndrome. This paper presents a case with pre-Eisenmenger patent ductus arteriosus complicated by pulmonary artery dissection, and explains how she was surgically treated.
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    Endovascular therapy of acute ischaemic stroke by interventional cardiologists: single-centre experience from Turkey
    (2014-11-01) GOKTEKIN, Omer; TASAL, Abdurrahman; UYAREL, Huseyin; VATANKULU, Mehmet Akif; SONMEZ, Osman; AY, Nuray; KUL, Seref; YAMAC, Hatice; ALTINTAS, Ozge; KARADELI, Hasan; Kolukisa, MEHMET; Aralasmak, AYŞE; Asil, TALİP; KAHRAMAN AY, NURAY; KOLUKISA, MEHMET; ARALAŞMAK, AYŞE; ASİL, TALIP
    Aims: We report our single-centre experience with the Solitaire AB self-expanding retrievable stent system in patients with acute ischaemic stroke.
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    PublicationOpen Access
    Effects of ischemic preconditioning and iloprost on myocardial ischemia-reperfusion damage in rats
    (2013-01-01) Ay, YASİN; Kara, Ibrahim; Aydin, CEMALETTİN; TEKER, Melike Elif; Senol, Serkan; Inan, BEKİR; BASEL, Halil; Uysal, Omer; Zeybek, RAHMİ; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; İNAN, BEKİR; UYSAL, ÖMER; ZEYBEK, RAHMİ
    This study investigates the effects of cardiac ischemic preconditioning and iloprost on reperfusion damage in rats with myocardial ischemia/reperfusion. 38 male Wistar Albino rats used in this study were divided into 5 groups. The control group (Group 1) (n=6), ischemia/reperfusion (IR) group (Group 2) (n=8), cardiac ischemic preconditioning (CIP) group (Group 3) (n=8), iloprost (ILO) group (Group 4) (n=8), and cardiac ischemic preconditioning + iloprost (CIP+ILO) group (Group 5) (n=8). Pre-ischemia, 15 minutes post-ischemia, 45 minutes post-reperfusion, mean blood pressure (MBP), and heart rates (HR) were recorded. The rate-pressure product (RPP) was calculated. Post-reperfusion plasma creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), troponin (cTn) vlaues, and infarct size/area at risk (IS/AAR) were calculated from myocardial tissue samples. Arrhythmia and ST segment elevations were evaluated during the ischemia and reperfusion stages. Although the MBP, HR, RPP values, biochemical parameters of CK-MB and LDH levels, IS/AAR rates, ST segment elevation values were found to be similar in CIP and CIP+ILO groups and the IR and ILO groups (p>0.05), CIP-containing group values had a positively meaningful difference (p<0.05) compared with the IR and ILO group. While mild-moderate findings of damage were observed in Group 3 and Group 5, severely findings of damage were releaved in Group 2 and Group 4. The arrhythmia score of the ILO group was meaningfully lower (F: 41.4, p<0.001) than the IR group. We can conclude that the effects of myocardial reperfusion damage can be reduced by cardiac ischemic preconditioning, intravenous iloprost reduced the incidence of ventricular arrhythmia associated with reperfusion, and its use with CIP caused no additional changes.
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    Improvements in quality of life in septuagenarians versus octogenarians undergoing trans-catheter aortic valve replacement
    (2016-01-01T00:00:00Z) KAHRAMAN AY, Nuray; AY, YASİN; Sonmez, Osman; Vatankulu, Mehmet Akif; Goktekin, Omer; KAHRAMAN AY, NURAY; AY, YASİN
    Background Very elderly patients represent a distinct patient group in clinical setting in terms of a decision for trans-catheter aortic valve replacement (TAVR) when one considers the potential improvement in the quality of life (QoL) on one hand and the benefit to risk ratio on the other. This study aimed to compare functional and QoL outcomes of TAVR between octogenarians and septuagenarians. Methods This prospective cohort study included 136 elderly patients (70 to 89 years of age), who underwent transfemoral TAVR due to degenerative aortic stenosis. Patients were allocated into one of the following age groups: septuagenarians (n = 67) and octogenarians (n = 69). Preoperative and early postoperative clinical parameters were recorded. In addition, QoL of the patients was evaluated using SF-36 questionnaire preoperatively and six month postoperatively. Results Groups were similar in terms of early postoperative mortality and morbidity parameters. The mean New York Heart Association (NYHA) class improved after TAVR in both groups. In addition, all SF-36 norm-based scale and SF-36 summary scale scores improved significantly in both groups during the postoperative period. Postoperatively, physical functioning, general health and physical component summary scores were significantly better in the septuagenarian group (P = 0.02, 0.01, 0.03, respectively). Conclusion Although the improvement in the QoL in terms of physical health was more marked in septuagenarians than in octogenarians, substantial benefits on the QoL and particularly on mental health seem to justify re-consideration of TAVR indications in the very elderly.
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    PublicationOpen Access
    A Case of Spontaneous Multivessel Coronary Artery Spasm That Underwent Stent Implantation Accompanying ST Segment Elevation on Inferior Electrocardiographic Leads
    (2016-01-01T00:00:00Z) KAHRAMAN AY, Nuray; Nasifov, Muharrem; Goktekin, Omer; KAHRAMAN AY, NURAY
    Coronary artery spasm is usually defined as a focal constriction of a coronary artery segment, which is reversible, and causes myocardial ischaemia by restricting coronary blood flow. A coronary spasm may rarely compromise all three epicardial arteries simultaneously. We present a case of severe coronary spasm afflicting all coronary arteries accompanying an ST segment elevation in leads D2-D3 and aVF.