Person: ÖZTEN KANDAŞ, NUR
Loading...
Status
Kurumdan Ayrılmıştır
Organizational Units
11 results
Search Results
Now showing 1 - 10 of 11
Publication Metadata only Comparison of laser and ozone treatments on oral mucositis in an experimental model(2017-04-01T00:00:00Z) BAYER, SUZAN; Kazancioglu, Hakki Oguz; Acar, Ahmet Huseyin; Demirtas, Nihat; ÖZTEN KANDAŞ, NUR; BAYER, SUZAN; ÖZTEN KANDAŞ, NUROral mucositis (OM) induces severe pain and limits fundamental life behaviors such as eating, drinking, and talking for patients receiving chemotherapy or radiotherapy. In addition, through opportunistic microorganisms, OM frequently leads to systemic infection which then leads to prolonged hospitalization. Severe lesions often adversely affect curative effects in cancer cases. Therefore, the control of OM is important for oral health quality of life and prognosis. Low-level laser therapy (LLLT) and ozone may be useful to accelerate wound healing. In this study, 24 Sprague-Dawley rats were divided into three groups as control, ozone, and laser groups. All groups received 5-fluorouracil intraperitoneally and trauma to the mouth pouch with a needle. After the formation of OM in the mouth, the control group had no treatment; the ozone group was administered ozone, and the laser group, LLLT. Then, all groups were sacrificed and basic fibroblast growth factor (bFGF), transforming growth factor (TGF-beta), and platelet-derived growth factor (PDGF) were evaluated in all groups. LLLT was determined to be statistically significantly more effective than ozone on FGF and PDGF. However, in respect of TGF-beta, no statistically significant difference was observed between the groups. In conclusion, within the limitations of this study, LLLT is more effective than ozone. However, further studies on this subject are required.Publication Metadata only Mikroenkapsüle edilen paratiroid hücrelerinin in-vitro optimizasyonu(2017-12-01) YUCESAN, Emrah; GONCU, Beyza; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; ERSOY, YELİZ EMİNE; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHAN; BAŞOĞLU, HARUN; GÖNCÜ, BEYZA SERVET; ÖZTEN KANDAŞ, NUR; ERSOY, YELIZ EMINE; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHANPublication Metadata only NEW TRANSPORT SOLUTION FOR PARATHYROIDALLOTRANSPLANTATION (FR) (NFR)(2017-09-27) GONCU, Beyza; OZDEMIR, Burcu; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; KESKİN TOKA, Cemile; YUCESAN, Emrah; KAZANCIOĞLU, RÜMEYZA; AYŞAN, MUSTAFA ERHAN; GÖNCÜ, BEYZA SERVET; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; KAZANCIOĞLU, RÜMEYZA; AYŞAN, MUSTAFA ERHANPublication Open Access Cancer chemoprevention research with selenium in the post-SELECT era: Promises and challenges.(2016-01-01) LÜ, J; ZHANG, J; JIANG, C; DENG, Y; Özten, NUR; BOSLAND, MC; ÖZTEN KANDAŞ, NURThe negative efficacy outcomes of double-blinded, randomized, placebo-controlled Phase III human clinical trials with selenomethionine (SeMet) and SeMet-rich selenized-yeast (Se-yeast) for prostate cancer prevention and Se-yeast for prevention of non-small cell lung cancer (NSCLC) in North America lead to rejection of SeMet/Se-yeast for cancer prevention in Se-adequate populations. We identify two major lessons from the outcomes of these trials: 1) The antioxidant hypothesis was tested in wrong subjects or patient populations. 2) The selection of Se agents was not supported by cell culture and preclinical animal efficacy data as is common in drug development. We propose that next-generation forms of Se (next-gen Se), such as methylselenol precursors, offer biologically appropriate approaches for cancer chemoprevention but these are faced with formidable challenges. Solid mechanism-based preclinical efficacy assessments and comprehensive safety studies with next-gen Se will be essential to re-vitalize the idea of cancer chemoprevention with Se in the post-SELECT era. We advocate smaller mechanism-driven Phase I/II trials with these next-gen Se to guide and justify future decisions for definitive Phase III chemoprevention efficacy trials.Publication Open Access Synthesis and biological evaluation of novel coumarin-chalcone derivatives containing urea moiety as potential anticancer agents(2017-12-01) ZENGİN KURT, BELMA; ÖZTEN KANDAŞ, NUR; DAĞ, AYDAN; SÖNMEZ, FATİH; KÜÇÜKİSLAMOĞLU, MUSTAFA; ÖZTEN KANDAŞ, NURPublication Metadata only Interactive effects of 9-cis-retinoic acid and androgen on proliferation, differentiation, and apoptosis of LNCaP prostate cancer cells.(2017-01-01) ESKRA, JN; KUIPER, JW; WALDEN, PD; BOSLAND, MC; Özten, NUR; ÖZTEN KANDAŞ, NURPublication Metadata only Low Dose Genistein Unlikely Induces Proliferation of PC3 Cells(2017-05-25) TERZİOĞLU UŞAK, ŞULE; ÖZTEN KANDAŞ, NUR; TERZİOĞLU, ŞULE; ÖZTEN KANDAŞ, NURPublication Metadata only Bezmialem Taşıma Solüsyonu®’nun Soğuk İskemi Süresince Verimliliğinin Paratiroid Hücreleri İncelenerek Belirlenmesi(2017-12-03) GONCU, Beyza; YUCESAN, Emrah; OZDEMIR, Burcu; KESKİN TOKA, Cemile; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHAN; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHANPublication Metadata only Ameliyat sonrası gelişen peritoneal yapışıklığın önlenmesinde sodyum aljinat ve saf aljinat etkinliğinin enflamasyon açısından incelenmesi(2017-10-29) GONCU, Beyza; YIĞMAN, SAMET; BAŞOĞLU, HARUN; YUCESAN, Emrah; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHAN; YIĞMAN, SAMET; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHANPublication Metadata only Paratiroit Hücrelerinin İn Vitro Mikroenkapsülasyonu(2017-11-30) GONCU, Beyza; YUCESAN, Emrah; HÜSEYİNBAŞ, Önder; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHAN; GÖNCÜ, BEYZA SERVET; BAŞOĞLU, HARUN; ÖZTEN KANDAŞ, NUR; AKBAŞ, FAHRİ; AYŞAN, MUSTAFA ERHAN