Person: İZZETTİN, FIKRET VEHBI
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Publication Open Access Determination of Potential Drug-Drug Interactions Using Various Software Programs in a Community Pharmacy Setting(2019-03-01T00:00:00Z) SANCAR, MESUT; Kasik, Aksa; OKUYAN, BETÜL; Batuhan, Sevda; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBIObjectives: The aim of the present study was to compare various software programs in detecting potential drug-drug interactions in a community pharmacy setting. Materials and methods: Details of prescriptions were collected from 50 community pharmacies located in İstanbul in March and April 2015 (two days per week). From each pharmacy, the first 20 prescriptions that included more than one drug were collected to evaluate potential drug-drug interactions. The following software programs were utilized to detect potential drug-drug interactions: micromedexsolutions.com, medscape.com, and drugs.com. The number of potential interactions detected by the software programs was determined. Results: At least one potential drug-drug interaction was detected in 39.2% of the 1000 prescriptions by one of the software programs. According to the rates of total drug-drug interactions gathered from various software programs, these programs gave the following results: medscape.com 33.3%, drugs.com 31.3%, and micromedexsolutions.com 21.2%. Conclusion: After comparing different software programs, the potential drug-drug interactions found by the programs proved to be different. Therefore, we recommend that pharmacists confirm with a different program before making a decision when they detect clinically significant potential drug-drug interactions.Publication Open Access Insight into Turkish Community Pharmacists’ Services in the First Wave of the COVID-19 Pandemic(2021-06-01T00:00:00Z) Okuyan, Betül; İzzettin, Fikret Vehbi; BEKTAY, MUHAMMED YUNUS; İZZETTİN, FIKRET VEHBIPublication Open Access Time to change to improve health: clinical pharmacy and pharmaceutical care education in Turkey(2020-05-01T00:00:00Z) Bektay, Muhammed Yunus; Sancar, Mesut; Al-Ezzı, Saad Ahmed Ali; BEKTAY, MUHAMMED YUNUS; AL-EZZI, SAAD AHMED ALİ; İZZETTİN, FIKRET VEHBIThe practice of clinical pharmacy had a positive impact on the profession by giving pharmacists more job opportunities. Moreover, the pharmacy began to gain the status it deserved, which was lost many years ago. In this paper, we aimed to give a brief explanation of the clinical pharmacy philosophy and definition of pharmaceutical care. What are the general and specific roles of clinical pharmacists in the modern world healthcare system? Also, how to implement clinical pharmacy in education to obtain competent pharmacists. We shared our observation and experience, specifically on the progress of implementation of clinical pharmacy education in Turkey. The stepwise method has been successfully followed in the implementation of clinical pharmacy education in Turkey. In the undergraduate program, the first step taken was the addition of clinical courses, such as the role of clinical pharmacy, patient education, etc. and practical hospital rounds (internal medicine, pediatrics, and surgery). The post-graduate program, such as master (MSc) and doctoral (Ph.D.) degrees, also offered to prepare clinically oriented pharmacy academicians. The continuous education programs were structured to implement clinical pharmacy idea for the pharmacists in practice. In conclusion, the stepwise approach significantly smoothed the transition from the product-oriented to the patient-oriented pharmacy education. Moreover, the adoption of the skills education system to educate pharmacists needs to review the policy regularly and gradually change it accordingly.Publication Open Access Evaluation of satisfaction and internet self-efficacy of inquirers using an internet-based drug information centre(2019-02-01T00:00:00Z) Izzettin, FİKRET VEHBİ; YILMAZ, ZAHİT; OKUYAN, BETÜL; SANCAR, MESUT; İZZETTİN, FIKRET VEHBIObjectives: This study aimed to evaluate the satisfaction level of inquirers of an internet-based drug information centre along with the internet usage abilities and habits of individuals who had previously utilised services from an internet-based drug information centre in Turkey. Methods: The first 100 individuals who received medication consultancy from the webpage entitled “www.ilacpedia.com” and consented to participate in the study were included in this study. This website is an internet-based drug information centre. Participants' data were collected using a participant data form and the Internet Self-efficacy Scale. Results: The mean age of participants was 37.92 ± 12.32 years (71 female). It was found that 89% of the individuals who received pharmaceutical consultation from the internet-based drug information service believed that the information that they received was enough to solve their problem. The internet self-efficacy scale scores indicated the highest score on the decomposition subscale (20.94 ± 6.18) and the lowest on the communication subscale (9.77 ± 3.57). Conclusions: The present study revealed that the internet-based drug information service provided by clinical pharmacists contributed positively to users' satisfaction, thus indicating the importance of the involvement of clinical pharmacists in this process.Publication Open Access Adaptation of Chronic Kidney Disease-Self Management Knowledge Tool (CKD-SMKT) into Turkish(2021-09-01T00:00:00Z) Altiparmak, Oznur; İZZETTİN, Fikret Vehbi; OKUYAN, BETÜL; ARIKAN, İZZET HAKKI; SANCAR, MESUT; İZZETTİN, FIKRET VEHBIObjective: The aim of the study is adaptation of Chronic Kidney Disease-Self Management Tool (CKD-SMKT) into Turkish language.Publication Open Access Identification of Drug-Related Problems and Investigation of Related Factors in Patients with COVID-19: An Observational Study(2022-12-01) Bektay M. Y.; Sancar M.; Okyaltırık F.; Durdu B.; İzzettin F. V.; BEKTAY, MUHAMMED YUNUS; OKYALTIRIK, FATMANUR; DURDU, BÜLENT; İZZETTİN, FIKRET VEHBIObjective: Clinical prognosis of coronavirus disease-19 (COVID-19) may be severe and unexpected. Patients may quickly progress to respiratory failure, infections, multiple organ dysfunction, and sepsis. The main objective of this study is to investigate the drug-related problems of patients with COVID-19 and related factors. Method: A prospective observational study was conducted on patients with COVID-19 between September 2020 and May 2021. Patients’ demographics, comorbid diseases, prescribed medicines and laboratory findings were recorded. Drug-related problems (DRPs) were identified by a clinical pharmacist according to recent guidelines, UpToDate® clinical decision support system and evidence-based medicine. Results: The median age of 107 patients was 64 and 50.46% of them were male. The median number of comorbidities was 3 (2-4) per patient. The majority of the patients had at least one comorbidity (88.79%) other than COVID-19 and the most frequent comorbidities were hypertension, diabetes mellitus and coronary artery disease. The total number of DRPs was recorded as 201 and at least one DRP was seen in 75 out of 107 patients. The median number of DRPs was 2 (0-8). In multivariate model, number of comorbidities (odss ratio (OR)=1.952; 95% confidence interval (CI)=1.07-3.54, p<0.05, number of medications (OR=1.344; 95% CI=1.12-1.61, p<0.001), and serum potassium levels (OR=5.252; 95% CI=1.57-17.56, p<0.001) were the factors related with DRP. Conclusion: This study highlights the DRPs and related factors in patients with COVID 19 in hospital settings. Considering unknown features of the infection and multiple medication use, DRPs are likely to occur. It would be beneficial to consider the related factors in order to reduce the number of the DRPs.