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Now showing 1 - 10 of 142
  • PublicationMetadata only
    Determination of Pharmaceutical Care Needs of COVID-19 Patients in the 1st Wave of Pandemic
    (2021-09-08T00:00:00Z) Gökçe, Naçize; Bektay, Muhammed Yunus; İzzettin, Fikret Vehbi; BEKTAY, MUHAMMED YUNUS; İZZETTİN, FIKRET VEHBI
    Turkey In 2020 COVID-19 pandemic spread all over the world. A multidisciplinary approach isnecessary for the treatment. The aim of this study is to determine the pharmaceutical care need of COVID-19 patients in the 1st wave of the pandemic. A retrospective, observational study was conducted. After ethical approval was given with 13/274 number, prescription records were investigated by a clinical pharmacist (CP). drug-related problems (DRP)identified through prescription examination. Study was held in 2 branches (i) hospitalized patients (HP) where CP is present and (ii) ambulatory care patients (AP). In this study 183HP and 182 AP patients prescriptions were examined. Half of the participants were female89 (%48.6), 83 (%45.6) for HP and AP respectively. The mean±SD age for HPs and APs were42±18, 42,5±16 respectively. Many participants had multiple comorbidities, in HPs 91(%49.5) at least have 2 or more existing diseases. The median medication number of HPsand APs were 7, 5 respectively. CP identified DRP events for HPs and APs 144, 306respectively. The most common DRP for HPs was using ondansetron instead of metoclopramide. On the other hand, the most prevalent DRP for APs was lack of any gastroprotective medication. DRPs are probable events. Our results demonstrated that HPshad a lower number of DRPs. This points out that CP is a valuable asset to prevent DRPs. In conclusion, every setting where a clinical pharmacist is present should be involved in the healthcare and take responsibility.
  • PublicationMetadata only
    Determination of CYP2C19 polymorphisms, adverse drug reaction, and medication adherence in patients utilized selective serotonin reuptake inhibitors
    (2015-02-01T00:00:00Z) Deniz, Semanur; SANCAR, MESUT; OKUYAN, BETÜL; ATA, PINAR; Bingol-Ozakpinar, Ozlem; TALAS, Anil; GUNES, Tufan; CALISKAN, Mecit; Izzettin, Fikret Vehbi; İZZETTİN, FIKRET VEHBI
  • PublicationMetadata only
    Assessment of pharmacy technicians- attitudes and responsibilities toward patient oriented pharmacy practices at community pharmacy
    (2012-02-01T00:00:00Z) SANCAR, MERT; OKUYAN, BETÜL; Tamyuksel, E.; Izzettin, FİKRET VEHBİ; İZZETTİN, FIKRET VEHBI
  • PublicationMetadata only
    Assessment of attitude and knowledge in patients utilized disposable insulin pens at community pharmacy setting
    (2016-04-01T00:00:00Z) OKUYAN, BETÜL; Semerci, Z.; Odabasi, G.; Izzettin, FİKRET VEHBİ; SANCAR, MERT; İZZETTİN, FIKRET VEHBI
  • PublicationMetadata only
    Assessment of individuals- knowledge and attitudes towards utilization of analgesics at community pharmacy setting
    (2019-02-01T00:00:00Z) Torun, B.; ÖZKAN, ONUR CAN; Zortul, H.; Kesedar, S.; Izzettin, FİKRET VEHBİ; SANCAR, MERT; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBI
  • PublicationMetadata only
    Impact of a pharmaceutical care program on glycemic control, medication knowledge and medication adherence levels of type 2 diabetic patients residing at a nursing home
    (2017-02-01T00:00:00Z) Saglam, Nimet; Apikoglu-Rabus, Sule; OKUYAN, BETÜL; Izzettin, Fikret V.; Yildirim, NURAN; İZZETTİN, FIKRET VEHBI
  • PublicationMetadata only
    Drug-drug interactions identified for cardiac transplant recipients
    (2017-02-01T00:00:00Z) Apikoglu-Rabus, Sule; RABUS, Murat B.; Ozkan, Oznur; ŞAHİN, YELİZ; Izzettin, Fikret V.; İZZETTİN, FIKRET VEHBI
  • PublicationMetadata only
    Are Students Using Pharmacological Cognitive Enhancement More Successful?
    (2021-09-08T00:00:00Z) Sümbül Şekerci, Betül; Bektay, Muhammed Yunus; Bildik, Özlem; İzzettin, Fikret Vehbi; SÜMBÜL ŞEKERCİ, BETÜL; BEKTAY, MUHAMMED YUNUS; BİLDİK, ÖZLEM; İZZETTİN, FIKRET VEHBI
    Introduction: The use of psychostimulant drugs to increase academic success is common among young people, especially medical students. However, the effect of psychostimulants on academic success not clear in the current literature. Materials and Methods: A structured online survey was carried out with 431 undergraduate students in different faculties of Medicine in Turkey. Comparisons between groups, correlation and regression analysis about associated variables were made. The academic performance of the students was evaluated with grade point average (GPA) score. Also, academic success, academic anxiety, study performance, sleep quality and pharmacological knowledge levels were questioned with the scale based on self-evaluations. Results: 23 (5.4%) healthy students reported using psychostimulants to improve academic success. There was no significant difference in age, gender, semester, objective (GPA score) and subjective (self-report) assessment of success between users and non-users. But most of the users evaluated that the psychostimulants are useful. Smoking and increased knowledge level of pharmacology are risk factors for psychostimulant use. Conclusion: We could not find a relationship between academic success and pharmacological cognitive enhancement. Psychostimulant use had an positive effect on self-assessment of students. It can support the hypothesis that the psychostimulants has a motivational contribution rather than a purely pharmacological effect. The relationship of psychostimulants with alcohol and smoking should be examined in detail, and users should be questioned in terms of susceptibility to risky behaviors and addiction.
  • PublicationMetadata only
    Protective effect of ferulic acid on cisplatin induced nephrotoxicity in rats
    (2017-09-01T00:00:00Z) Bami, Erliasa; Ozakpinar, Ozlem Bingol; Ozdemir-Kumral, Zarife Nigar; Koroglu, Kutay; ERCAN, FERİHA; CIRAKLI, Zeynep; ŞEKERLER, TURGUT; Izzettin, FİKRET VEHBİ; SANCAR, MESUT; OKUYAN, BETÜL; İZZETTİN, FIKRET VEHBI
    This study aims to determine the potential protective effects of ferulic acid against cisplatin-induced nephrotoxicity and to compare its effect with curcumin, a well-known protective agent against cisplatin- induced toxicity in rats. Administration of cisplatin resulted in high BUN (Blood Urea Nitrogen), creatinine, MDA (Malondialdehyde), MPO (Myeloperoxidase), TOS (Total Oxidative Status), PtNT (Protein Nitrotyrosine) levels (p < 0.05). Histological observations showed abnormal morphology of kidney; in addition with appearance of TUNEL positive cells indicating apoptosis in cisplatin administered group. HO-1 (Heme Oxygenase-1) levels measured by RT-PCR (Real Time Polymerase Chain Reaction), and TAS (Total Antioxidative Status) revealed antioxidant depletion due to cisplatin toxicity in animals (p < 0.05). All parameters showed improvement in groups treated with ferulic acid (p < 0.05). Ferulic acid treatment was found significant in preventing oxidative stress, increasing antioxidative status and regaining histological parameters to normal, indicating nephroprotective and antioxidant effects of this phenolic compound.
  • PublicationMetadata only
    The role of the clinical pharmacist in patient education and monıtoring of patients under warfarin treatment
    This study was carried out on patients who were under anticoagulation treatment with warfarin, at the outpatient cardiology clinic. The aim was to determine the effectiveness of pharmacist consultation, education, and intervention on each patient-s therapeutic results. A cross-sectional randomized trial has been done. Twenty-five patients were included in the study. The Oral Anticoagulation Knowledge (OAK) Test, Short Form-36 (SF-36) and Duke Anticoagulation Satisfaction Scale (DASS) were applied. Patients resumed their routine anticoagulation treatment and INR and complications were recorded during the study. Additionally, patients received patient education, consultation on lifestyle and anticoagulant usage issues from a pharmacist. The same tests were applied again to the patients on the 90th day of the study and the results were compared with the initial test. Maintenance of INR within the target range and complication rates were compared before and after the intervention. Pre-test and post-test results of the patients revealed statistically significant improvements on the physical and mental score components of the SF-36 (p = 0.001; p = 0.001), OAK test scores (p <= 0.001) and the (negative) -limitations- and -burdens- and -positive effects- components of the DASS (p = 0.005; p < 0.001; p = 0.001). The successful maintenance of INR within target range was significantly higher (p = 0.027). The positive effects of pharmacist consultation and education on therapeutic results were demonstrated.