Person: BÜLBÜLOĞLU, ERTAN
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Publication Metadata only The effects of L-carnitine and N-acetylcysteine on carbontetrachloride induced acute liver damage in rats(2013-01-01T00:00:00Z) Cetinkaya, A.; Kantarceken, B.; Bulbuloglu, ERTAN; Kurutas, E. B.; Ciralik, H.; Atli, Y.; BÜLBÜLOĞLU, ERTANAim: To investigate the effects of L-carnitine (LCAR) and N-acetylcysteine (NAC) on carbon tetrachloride (CCl4)-induced acute liver damage in rats.Publication Metadata only Predictive role of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios for diagnosis of acute appendicitis during pregnancy(2015-11-01T00:00:00Z) Yazar, Fatih Mehmet; Bakacak, Murat; Emre, Arif; Urfalioglu, Aykut; Serin, Salih; Cengiz, Emrah; Bulbuloglu, ERTAN; BÜLBÜLOĞLU, ERTANAcute appendicitis (AA) is not uncommon during pregnancy but can be difficult to diagnose. This study evaluated the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in addition to conventional diagnostic indicators of the disease to diagnose AA during pregnancy. Age, gestational age, white blood cell (WBC) count, Alvarado scores, C-reactive protein (CRP), lymphocyte count, NLR and PLR were compared among 28 pregnant women who underwent surgery for AA, 35 pregnant women wrongly suspected as having AA, 29 healthy pregnant women, and 30 nonpregnant healthy women. Mean WBC counts and CRP levels were higher in women with proven AA than in those of control groups (all p < 0.05). Among all the groups, the median NLR and PLR were significantly different in women with proven AA (all p < 0.05). Receiver operating characteristic analysis was used to determine cut-off values for WBC count, CRP, lymphocyte count, NLR and PLR, and multiple logistic regression analysis showed that NLR and PLR used with routine methods could diagnose AA with 90.5% accuracy. Used in addition to routine diagnostic methods, NLR and PLR increased the accuracy of the diagnosis of AA in pregnant women. Copyright (C) 2015, Kaohsiung Medical University. Published by Elsevier Taiwan LLC. All rights reserved.Publication Metadata only Efficacy of the Evaluation of Inflammatory Markers for the Reduction of Negative Appendectomy Rates(2018-02-01T00:00:00Z) Yazar, Fatih Mehmet; Urfalioglu, Aykut; Bakacak, Murat; Boran, Omer Faruk; Bulbuloglu, ERTAN; BÜLBÜLOĞLU, ERTANUnnecessary appendectomy can cause complications; ways of reducing negative appendectomy rates (NAR) using biochemical and imaging methods are desirable. We retrospectively examined 640 patients who underwent appendectomy for suspected AA. Patients with histologically confirmed appendicitis were designated the positive appendectomy group (n = 565), whereas those with unconfirmed appendicitis were designated the negative appendectomy group (n = 75). The positive appendectomy group was subdivided into the non-perforated (n = 511) and perforated (n = 54) appendectomy groups according to pathology reports. We compared the age, sex, lymphocyte count, neutrophil percentage, pathologic positivity or negativity for appendicitis, C-reactive protein (CRP) level, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) of the patients. When the perforated, non-perforated, and negative appendectomy groups were compared, the highest CRP level, NLR, and PLR were evident in the perforated appendectomy group (p = 0.001), whereas the lowest neutrophil percentage was found in the non-perforated appendectomy group (p = 0.001). Multiple logistic regression analysis identified neutrophil percentage, CRP value, and NLR as independent variables and demonstrated that AA could be diagnosed with 88.9 % accuracy using the cutoff values determined. In patients with suspected AA, particularly in rural areas with limited access to advanced imaging modalities, the evaluation of neutrophil percentage, CRP level, and NLR, in combination with the findings of a physical examination, may aid diagnosis and reduce NAR.Publication Metadata only The comparison of the effects of hepatic regeneration after partial hepatectomy, silybum marinaum, propofol, N-acetylcysteine and vitamin E on liver(2012-01-01T00:00:00Z) Yormaz, S.; Bulbuloglu, ERTAN; Kurutas, E. B.; Ciralik, H.; Yuzbasioglu, M. F.; Yildiz, H.; Coskuner, I; Silay, E.; Kantarceken, B.; Goksu, M.; Senoglu, N.; Kale, I. T.; BÜLBÜLOĞLU, ERTANAim: We investigated the comparison of the effects of N-acetylcysteine, silybum marinaum, propofol, and vitamin E on liver hepatic regeneration after partial hepatectomy.Publication Metadata only Protective effects of laparoscopic sleeve gastrectomy on atherosclerotic and hemocytic parameters in obese patients(2018-09-01T00:00:00Z) Baykara, Murat; Yazar, Fatih Mehmet; Cengiz, Emrah; Bulbuloglu, ERTAN; BÜLBÜLOĞLU, ERTANObjectives:The aim of this study was to evaluate the effects of the change in the body mass index following laparoscopic sleeve gastrectomy on the vascular morphology structure and biochemical and hemocytic parameters. Material andPublication Metadata only The protective effects of ketamine and propofol in obstructive jaundice: an experimental study(2012-01-01T00:00:00Z) Yildiz, H.; Coskuner, I; Bulbuloglu, ERTAN; Silay, E.; Kurutas, E. B.; Dogan, Z.; Kantarceken, B.; Oksuz, H.; Senoglu, N.; Yuzbasioglu, M. F.; Cetinkaya, A.; Ciralik, H.; BÜLBÜLOĞLU, ERTANObjective: In this study, we investigated the protective effects of frequently used intravenous anesthetics (ketamine, propofol, thiopental, and fentanyl) in oxidative stress in a rat liver model of obstructive jaundice.Publication Metadata only Efficacy of P-Coumaric acid and Ellagic acid added to preservation solutions in transplantation(2021-04-14T00:00:00Z) YAZAR, Fatih Mehmet; URFALIOĞLU, Aykut; BORAN, Ömer Faruk; BAHAR, Abdulkadir; DAĞLI, Hasan; GÜL, Mehmet; İNANÇ TOLUN, Fatma; BULBULOGLU, ERTAN; BÜLBÜLOĞLU, ERTANPublication Metadata only Laparoscopic Sleeve Gastrectomy in Situs Inversus Totalis: a Case Report and Comprehensive Literature Review(2016-04-01T00:00:00Z) Yazar, Fatih Mehmet; Emre, Arif; AKBULUT, AHMET SAMİ; Urfalioglu, Aykut; Cengiz, Emrah; Sertkaya, Mehmet; Yildiz, Huseyin; Bulbuloglu, ERTAN; BÜLBÜLOĞLU, ERTANThe aim of this study is to review the reliability of laparoscopic obesity operations in patients with situs inversus totalis(SIT). A new case of SIT was presented together with a literature review of published English language studies on laparoscopic gastric banding (LAGB), laparoscopic gastric bypass (LRYGB), laparoscopic sleeve gastrectomy (LSG), laparoscopic obesity surgery (LOS), and SIT, accessed via PubMed and Google Scholar databases. The case is presented of a 21-year-old female patient who underwent LSG due to SIT. A total of 12 publications in literature matched the search criteria for LAGB, LRYGB, LSG, LOS, and SIT, which reported LAGB in five cases, LRYGB in four cases, and LSG in four cases. In the rare event of SIT, LOS can be safely used following good evaluation.Publication Metadata only Idiopathic Granulomatous Mastitis: Overcoming this Important Clinical Challenge(2018-05-01T00:00:00Z) Emre, Arif; AKBULUT, AHMET SAMİ; Sertkaya, Mehmet; Bitiren, Muharrem; Kale, Ilhami Taner; Bulbuloglu, ERTAN; Yurttutan, Nursel; BÜLBÜLOĞLU, ERTANThe aim of this study was to determine possible risk factors for recurrence development in patients with idiopathic granulomatous mastitis (IGM). Demographic, clinical, radiologic, and histopathologic characteristics of 34 consecutive patients with IGM were retrospectively reviewed. Also, 32 patients who were informed about recurrence status were divided into non-recurrent (n = 27) and recurrent (n = 5) groups. Both groups were compared for demographic and clinical parameters. This study included 34 female patients with IGM aged between 26 and 70 years (median: 38 years). During the follow-up period, no recurrence occurred in 27 patients whereas recurrence developed in 5 patients. No significant difference was found between the groups with respect to age, lesion size, breast-feeding, number of child, marital status, use of oral contraceptive, familial or personal tuberculosis history, PPD test, smoking, lesion side, lesion location on the breast, and treatment choice. The diagnostic tools of the IGM as follows: tru-cut (n = 18); incisional (n = 6); tru-cut + incisional (n = 5); tru-cut + excisional (n = 2); tru-cut + FNAB (n = 1); FNAB + excisional (n = 1) and FNAB (n = 1). Treatment options were as follow: antibiotics + drainage (n = 10); antibiotics + drainage + corticosteroid (n = 9); wait and watch (n = 6); corticosteroid (n = 3); antibiotics + antituberculous (n = 1); antituberculous (n = 1); antibiotics + breast conserving surgery + chemotherapy (n = 1); modified radical mastectomy+ chemotherapy+ radiotherapy (n=1); and no available (n = 2). This study shows that no demographic and clinical data contributes to the development of recurrence disease. To give a strong message, this study should be supported by other high volume and prospective studies.Publication Metadata only The evaluation of postural stability and fall risk in morbidly obese preoperative bariatric patients: A cross-sectional study(2021-09-01T00:00:00Z) YILMAZ, Nurdan; BULBULOGLU, ERTAN; BÜLBÜLOĞLU, ERTAN