Person: VEHAPOĞLU TÜRKMEN, AYSEL
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Publication çocukta kayısı sülfirizasyonuna bağlı kronik trakeal ödem ve solunum sıkıntısı(2018-09-27T00:00:00Z) Vehapoğlu Türkmen, Aysel; Çakır, Erkan; Uzuner, Selçuk; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIR, ERKAN; UZUNER, SELÇUKPublication Are Growing Pains Related to Vitamin D Deficiency? Efficacy of Vitamin D Therapy for Resolution of Symptoms(2015-01-01) Vehapoglu, AYSEL; Turel, Ozden; TURKMEN, Serdar; INAL, Berrin Belcik; Aksoy, TURGUT; OZGURHAN, Gamze; ERSOY, Murat; VEHAPOĞLU TÜRKMEN, AYSEL; TÜREL, ÖZDEN; AKSOY, TURGUTObjectives: The aim of this study was to investigate the 25-hydroxyvitamin D [25(OH)D] status of children with growing pains and to evaluate the efficacy of vitamin D treatment on the resolution of pain symptoms. Subjects and Methods: One hundred and twenty children with growing pains were included in a prospective cohort study. Serum 25(OH)D and bone mineral levels were measured in all subjects at the time of enrollment. The pain intensity of those with vitamin D deficiency was measured using a pain visual analog scale (VAS). After a single oral dose of vitamin D, the pain intensity was remeasured by means of the VAS at 3 months. The 25(OH)D levels and VAS scores before and after oral vitamin D administration were compared by means of a paired Student-s t test. Results: In the 120 children with growing pains, vitamin D insufficiency was noted in 104 (86.6%). Following vitamin D supplementation, the mean 25(OH)D levels increased from 13.4 +/- 7.2 to 44.5 +/- 16.4 ng/ml, the mean pain VAS score decreased from 6.8 +/- 1.9 to 2.9 +/- 2.5 cm (a mean reduction of -3.8 +/- 2.1, p < 0.001) and the difference was statistically significant. Conclusion: Supplementation with oral vitamin D resulted in a significant reduction in pain intensity among these children with growing pains who had hypovitaminosis D. (C) 2015 S. Karger AG, BaselPublication Role of circulating adipocytokines vaspin, apelin, and visfatin in the loss of appetite in underweight children: a pilot trial(2015-09-01) Vehapoglu, AYSEL; USTABAS, Feyza; OZGEN, Tolga I.; Terzioglu, Sule; CERMIK, Banu B.; OZEN, Omer F.; VEHAPOĞLU TÜRKMEN, AYSEL; USTABAŞ KAHRAMAN, FEYZA; ÖZGEN, İLKER TOLGA; TERZİOĞLU, ŞULE; ÖZER, ÖMER FARUKObjectives: To investigate serum concentrations of vaspin, apelin, and visfatin in underweight children and their association with anthropometric and nutritional markers of malnutrition.Publication Çocukluk Çağı Nefrotik Sendromunda Ortalama Trombosit Hacminin Önemi(2016-01-01T00:00:00Z) GÖKNAR, NİLÜFER; DOĞAN DEMİR, AYŞEGÜL; VEHAPOĞLU TÜRKMEN, AYSEL; ÖKTEM, FARUK; DOĞAN DEMİR, AYŞEGÜL; VEHAPOĞLU TÜRKMEN, AYSELPublication Is molluscum contagiosum related to zinc deficiency in children? Effectiveness of oral zinc sulfate therapy in lesion regression.(2021-11-01T00:00:00Z) Vehapoglu, Aysel; VEHAPOĞLU TÜRKMEN, AYSELPublication Clinical symptoms and microbiological findings in prepubescent girls with vulvovaginitis.(2022-07-09T00:00:00Z) Vehapoglu, Aysel; Kıyak, Merve Celep; VEHAPOĞLU TÜRKMEN, AYSELPublication İntramuskuler seftriakson sonrası akut intravasküler hemoliz gelişen bir olgu sunumu(2014-06-01T00:00:00Z) RÜMEYSA, TUNA; VEHAPOĞLU TÜRKMEN, Aysel; ÇAKIR, FATMA BETÜL; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIR, FATMA BETÜLPublication Recurrent meningitis in a child with IgG3 subclass deficiency.(2014-08-01) VEHAPOGLU, A; OZGURHAN, G; DEMIR, AD; Uzuner, SELÇUK; NURSOY, MUSTAFA ATİLLA; TURKMEN, S; VEHAPOĞLU TÜRKMEN, AYSEL; UZUNER, SELÇUK; NURSOY, MUSTAFA ATİLLAPublication Thyroid Hormone Levels in Obese Children and Adolescents with Non-Alcoholic Fatty Liver Disease(2014-01-01) Torun, EMEL; Ozgen, Ilker Tolga; Gokce, Selim; Aydin, SİNEM; Cesur, YAŞAR; TORUN, EMEL; ÖZGEN, İLKER TOLGA; VEHAPOĞLU TÜRKMEN, AYSEL; AYDIN, SİNEM; CESUR, YAŞARObjective: We aimed to determine the association of thyroid functions with the components of metabolic syndrome (MS) and non-alcoholic fatty liver disease (NAFLD) in pediatric obese patients. Methods: The study included 109 obese children (aged 9-15 years) and a control group of 44 healthy age and gender-matched children of normal weight. NAFLD was diagnosed by conventional ultrasound examination. We assessed the anthropometric data and serum biochemical parameters including lipid profile, alanine aminotransferase (ALT), fasting glucose and insulin levels and thyroid stimulating hormone (TSH), free thyroxine (fT4) and free triiodothyronine (fT3) levels. The homeostasis model assessment of insulin resistance (HOMA-IR) was calculated as a measure of IR. Results: The mean age and gender distributions in the groups were similar (p=0.23). The mean body mass index (BMI) z-scores of obese children with grade 2-3 NAFLD were significantly higher than those of the obese children without hepatic steatosis (p<0.001). Mean ALT, triglyceride (TG) and LDL cholesterol increased and HDL-cholesterol significantly decreased as the hepatic steatosis increased (p<0.05). HOMA-IR levels in obese subjects with grade 2-3 NAFLD were significantly higher than those in both obese children without NAFLD and grade 1 NADFL (p=0.05 and 0.001, respectively). In the obese subjects, TSH levels were increased significantly as the degree of steatosis increased (p=0.04) but fT3 and fT4 levels were not different. In correlation analysis, TSH was significantly correlated with ALT, BMI SDS and the degree of steatosis. Conclusions: Obese children demonstrate an increase in TSH levels as the degree of steatosis increased.Publication Correlation of Brain Neuropeptide (Nesfatin-1 and Orexin-A) Concentrations with Anthropometric and Biochemical Parameters in Malnourished Children(2015-09-01) Kahraman, Feyza Ustabas; Vehapoglu, Aysel; Ozgen, Ilker Tolga; Terzioglu, Sule; Cesur, YAŞAR; Dundaroz, Rusen; VEHAPOĞLU TÜRKMEN, AYSEL; USTABAŞ KAHRAMAN, FEYZA; ÖZGEN, İLKER TOLGA; TERZİOĞLU, ŞULE; CESUR, YAŞAR; İŞCAN, AKINObjective: Malnutrition continues to be a leading cause of stunted growth in many countries. This study aimed to investigate serum nesfatin-1 and orexin-A levels in underweight children and the potential correlations of these levels with anthropometric and nutritional parameters. Methods: The study enrolled 44 prepubertal children (between 2 and 12 years of age) with thinness grades of 1-3 and 41 healthy age- and gender-matched children. The demographic, clinical and laboratory parameters including nesfatin-1 and orexin-A concentrations were compared between the two groups. The correlations of nesfatin-1 and orexin-A with biochemical and anthropometric parameters were investigated. The receiver operating characteristic (ROC) analysis were also performed for evaluating nesfatin-1 and orexin-A in distinguishing children with malnutrition from healthy controls. Results: Thyroid-stimulating hormone, vitamin B12 and insulin levels were significantly lower in the study group than controls (p=0.001, p=0.049 and p=0.033, respectively). Mean nesfatin-1 levels in the malnourished group was also significantly lower compared to the healthy controls (3871.2 ± 1608.8 vs. 5515.0 ± 3816.4 pg/mL, p=0.012). No significant difference was observed in the orexin-A levels between the two groups (malnourished vs. control groups: 1135.7 ± 306.0 vs. 1025.7 ± 361.6 pg/mL, p=0.141). Correlation analyses revealed a positive correlation of nesfatin-1 and a negative correlation of orexin-A with body mass index (BMI) z-score. ROC analysis demonstrated that nesfatin-1 and orexin-A cannot be used to distinguish children with malnutrition from healthy controls (AUC: 0.620, p=0.061 for nesfatin-1 and AUC: 0.584, p=0.190 for orexin-A). Conclusion: The positive correlation of nesfatin-1 and the negative correlation of orexin-A with BMI suggest that these neuropeptides may be a part of a protective mechanism in the maintenance of nutritional status and that they may have a role in regulating food intake in undernourished children.