Person: TUNCABOYLU, DENIZ CEYLAN
6 results
Search Results
Now showing 1 - 6 of 6
Publication Metadata only Pluronic Based Injectable Smart Gels with Coumarin Functional Amphiphilic Copolymers(2022-06-01T00:00:00Z) Alemdar, Mahinur; Tuncaboylu, Deniz Ceylan; Batu, Hatice Kubra; Temel, Binnur; TUNCABOYLU, DENIZ CEYLAN; TEMEL, BİNNURPublication Open Access Design of Biocompatible Multifunctional Hydrogels with Stearyl Methacrylate and Vinylpyrrolidone(2022-03-01T00:00:00Z) Kilic, Husna; TUNCABOYLU, Deniz Ceylan; Argun, Aslihan; ÖZTÜRK CİVELEK, DİLEK; TUNCABOYLU, DENIZ CEYLAN; ÖZTÜRK CİVELEK, DİLEKBiofunctionality and biocompatibility are essential when tissue or organs are supplemented or replaced with a polymer based material. Here, we prepared stearyl methacrylate (SM) and vinylpyrrolidone (VP) based biocompatible SM-x networks with self-healing and shape memory properties. The mole ratios were gradually changed from hydrophilic to hydrophobic units between 10 and 90% to obtain gels meeting the requirements in various potential bioapplications. In addition to having a time-dependent viscoelastic character, the mechanical properties of the gels can be controlled by the amount of SM introduced into the reaction medium. Low SM content gels cannot fully return to their initial modulus values, while the gels formed with concentrations >= 60% are completely reversible due to the dynamic hydrophobic interactions, which is also effective in the self-healing behavior. Moreover, all of the networks can completely recall their permanent shape in seconds. The viability of human skin fibroblast cells, seeded on SM-x hydrogels, closely related to the water contact angle of the structures, was found to be over 82% at all x values. In the light of the findings, the wide range of properties of SM-x gel samples may show significant potential to address needs in a variety of biomedical applications.Publication Metadata only Supramolecular poloxamer-based in situ gels with hyaluronic acid and cyclodextrins(2021-01-01T00:00:00Z) Secer, Sevgi; Ceylan Tuncaboylu, Deniz; TUNCABOYLU, DENIZ CEYLANMechanically enhanced poloxamer (F127)-based injectable hydrogels in the presence of hyaluronic acid (HA) and three types of cyclodextrin (CD) molecules were prepared. With the addition of HA to the F127 system, higher strain values to break down the interactions between the micelles were obtained. The formulations exhibit more frequency-dependent behavior than F127-HA gels with the inclusion of CD molecules. All the F127-HA-CD formulations containing alpha-, beta- and gamma-CD were found in the injectable range and the viscosity values increased considerably when mucin was added to the triple component formulations that prove the mucoadhesive properties of the gels.Publication Metadata only Preparation of semi-interpenetrating silk fibroin–polyacrylamide nanogels(2020-01-01T00:00:00Z) Tuncel, Mahinur; Ceylan Tuncaboylu, Deniz Ceylan; TUNCABOYLU, DENIZ CEYLANPublication Metadata only Rheological Analysis of Polysaccharide Hydrogels(2020-12-01T00:00:00Z) Tuncaboylu, Deniz Ceylan; TUNCABOYLU, DENIZ CEYLANPublication Metadata only Cyclodextrin-linked PVP/PEG supramolecular hydrogels.(2021-10-01T00:00:00Z) Kirmic Cosgun, Seyma Nur; Ceylan Tuncaboylu, Deniz Ceylan; TUNCABOYLU, DENIZ CEYLAN