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KIRAN, TUĞÇE

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    PublicationOpen Access
    A Six Sigma Trial For Reduction of Error Rates in Pathology Laboratory
    (2016-09-01) TURNA, Seval; Tosuner, ZEYNEP; Gucin, ZÜHAL; Kiran, TUĞÇE; Buyukpinarbasili, NUR; TASKIRAN, Olcay; Arici, DİLEK SEMA; TOSUNER, ZEYNEP; GÜCİN, ZÜHAL; KIRAN, TUĞÇE; BÜYÜKPINARBAŞILI, NUR; TURNA, SEVAL; ARICI, DILEK SEMA
    Objective: The aim of this study is to determine differences of levels of empathy among undergraduates in each year of their four-year programs of physiotherapy. Methods: During the 2014-2015 academic school year, 381 physiotherapy students were enlisted from two universities in Istanbul, one a foundation and the other a government university. The Turkish version of the Jefferson Scale of Physician Empathy was administered. Students were asked to indicate interest in particular physiotherapy specialties as well as their region of origin in Turkey. The Kruskal-Wallis analysis was used to determine differences among the four study years, and also to measure relationships between specialty interest, home-region, and empathy scores of the students. Empathy scores were also compared according to gender. Results: The difference of empathy scores between the students of the two universities was borderline significant (p=0.057). Empathy scores in both universities increased to a significant degree after school entrance and decreased in the final year. Levels of empathy did not change according to gender, specialty interest, or home-region (p=0.722, 0.524, and 0.309, respectively). Conclusions: This study points to the need for physiotherapy curricula that would enhance empathy and give students practice in exhibiting this valuable attribute. Additional studies are needed that would include larger study populations and track the same students year by year as to how and why their empathy levels change during their training.
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    Simultaneous mass-forming pseudoangiomatous stromal hyperplasia of the breast, axilla, and perineum.
    (2019-11-01T00:00:00Z) Kiran, T; Peker, A; Yilmaz, TF; Yildiz, S; TOPRAK, HÜSEYİN; YILMAZ, TEMEL FATİH; KIRAN, TUĞÇE; YILDIZ, ŞEYMA
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    BAŞ-BOYUNUN AYIRICI TANIDA ZORLUK OLUŞTURAN KEMİK-YUMUŞAK DOKU TÜMÖRLERİ: 190 OLGUNUN LİTERATÜR EŞLİĞİNDE DEĞERLENDİRMESİ
    (2020-12-01T00:00:00Z) Kıran, Tuğçe; Tuğrul, Selhattin; KIRAN, TUĞÇE; TUĞRUL, SELAHATTİN
    ÖzetGiriş:Baş-boyun bölgesi primer kemik ve yumuşak doku tümörleri açısından çok nadir bir yerleşim yeridir. Erişkin yaş grubunda sarkomların ancak % 5-15-i baş-boyun lokalizasyonludur. Bunların % 20-si kemik, % 80-i ise yumuşak doku kaynaklıdır. Bu retrospektif çalışmanın amacı baş-boyun lokalizasyonlu kemik-yumuşak doku tümörlerinin demografik özelliklerini ve tanı dağılımlarını literatür ile karşılaştırmalı olarak irdelemektir.Materyal-Metod:Üniversitemiz tıp fakültesi patoloji biriminde, 2015-2020 yılları arasında tanı almış, baş-boyun lokalizasyonlu ve kemik-yumuşak doku kaynaklı tümör olguları retrospektif olarak, hastane bilgi sisteminden taranmış, demografik özellikleri, lokalizasyonları ve tanılarına göre sınıflandırılmış, yüzde ve sayısal verileri, literatür ile karşılaştırılmıştır.Bulgular:Tüm olgular için ortalama yaş 40.8 olup, yaş aralığı 2-85 arasında değişmekte idi. Yumuşak doku kaynaklı olgularda ortalama yaş 42.2 (2-85) iken, kemik tümörlerinde ortalama yaş 34.4(8-70) idi. Tüm olguların %56-sı(n:107) erkek, %44-ü(n:83) kadındı. Baş-boyun bölgesindeki spesifik lokalizasyonlarına bakıldığında, 190 olgunun %28-i (n:53) en yüksek oranla boyun bölgesinde yer almaktaydı. Olguların %81-ini (n:154) yumuşak doku kaynaklı, %19-unu (n:36) kemik kaynaklı neoplazmlar oluşturmakta idi. Yumuşak doku tümörlerinin %93-ü (n:144) benign, %7-si (n:10) ise maligndi. Kemik tümörlerinin %88-i (n:32) benign, %6-sı (n:2) malign olup, %6-sı (n:2) kemiğin hematopoetik neoplazmları içinde yer alan Langerhans hücreli histiositozdu.Sonuç:Baş-boyun bölgesinin kompleks yapısı ile kemik-yumuşak doku tümörlerinin çeşitlilik gösteren histolojik özellikleri biraraya geldiğinde tanıda ve klinik yönetimde zorluklar kaçınılmaz olmaktadır. Bu çalışmada, bölümümüzde tanı almış baş-boyun yerleşimli mezenkimal tümörlerin demografik ve tanısal dağılımlarına, literatürle karşılaştırmalı olarak, ayna tutmaya çalıştık. Sonuç olarak, verilerin büyük ölçüde literatürle uyumlu olduğunu gözlemlemekle birlikte, çok merkezli geniş serilerle yapılacak çalışmaların, olguların bu çalışmada da irdelenen özelliklerini daha sağlıklı bir şekilde yansıtacağını düşünmekteyiz.
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    Histopathological Features of Paratesticular Solid Tumors: 5 Years Experience
    (2020-05-01T00:00:00Z) Çoban, Ganime; Yıldız, Pelin; Kıran, Tuğçe; Ersöz, Cevper; ÇOBAN, GANİME; YILDIZ, PELİN; KIRAN, TUĞÇE; ERSÖZ, CEVPER
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    False Positivity of Gallium-68 Dota-Octreotid PET/MR Secondary to cis-Retinoic Asid Treatment in a Patient with Neuroblastoma
    (2018-11-01T00:00:00Z) Cakir, FATMA BETÜL; Besli, L. Uslu; KIRAN, Tuğçe; ÇAKIR, FATMA BETÜL; KIRAN, TUĞÇE
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    Slow growing, painless facial mass
    (2020-08-01T00:00:00Z) Sonmez Ergun, Selma; KİRAZOĞLU, AHMET; KIRAN, Tuğçe; ERGÜN, SELMA; KİRAZOĞLU, AHMET; KIRAN, TUĞÇE
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    The expression of IgM is helpful in the differentiation of primary cutaneous diffuse large B cell lymphoma and follicle center lymphoma
    (2011-09-01T00:00:00Z) Demirkesen, Cuyan; Tuzuner, Nukhet; Esen, Tuğçe; Lebe, Banu; Ozkal, Sermin; KIRAN, TUĞÇE
    Diffuse large B-cell infiltration of the skin includes mainly primary cutaneous follicle center lymphoma (PCFCL) with diffuse architecture and diffuse large B cell lymphoma (PCDLBCL), leg type. Differentiation of these lymphomas on morphology may be troublesome. Immunohistochemistry panel, including CD20, CD79a, bcl-6, bcl-2, MUM-1, FOX-P1 is mandatory. However, in minority of cases, these markers would not suffice. In order to search the value of another marker, IgM, 30 cases of PCFCL and 10 cases of PCDLBCL, leg type were included in the study. As suggested in a recent literature, our study denoted that expression of IgM was useful as an additional tool for differentiation. (C) 2011 Elsevier Ltd. All rights reserved.
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    PublicationOpen Access
    Intravascular/Intralymphatic Histiocytosis: A Report of 3 Cases
    (2015-10-01T00:00:00Z) Demirkesen, Cuyan; Kiran, Tuğçe; Leblebici, Cem; Yucelten, Deniz; Aksu, Ayse Esra Koku; Mat, Cem; KIRAN, TUĞÇE
    Intravascular/intralymphatic histiocytosis (IV/ILH) is a rare, reactive cutaneous condition, with uncertain pathogenesis. It may be associated with various inflammatory and neoplastic diseases. Although the clinical presentation is various, the biopsies reveal dilated vessels, mostly lymphatics, containing aggregates of histiocytes within their lumina. We described 3 cases of IV/ILH with different clinical presentations. In the first case, the patient presented with lymphedema in the genital region without any underlying disease. However, the second and third cases had reticular erythematous skin lesions. The second case had common variable immunodeficiency disease, rheumatoid arthritis, inflammatory bowel disease, and a history of a lymphoproliferative lesion. The third case had metal prostheses at both his right and left knees. In all these 3 cases, histopathologic and immunohistochemical findings were similar to each other and to those cases reported in the literature. In addition, the third case was admixed with reactive angioendotheliomatosis. In the second case, the endothelium of the ectatic vessels expressed CD31 and CD34, but not D2-40/podoplanin, pointing out that these vessels were blood vessels rather than lymphatics, differing from the other 2 cases. In conclusion, we believe, the most convincing statement about IV/ILH is that it is not a distinct clinicopathologic entity, but a histopathologic feature found as a part of a constellation of inflammatory changes or many other conditions.
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    PublicationOpen Access
    The diagnostic ability of core needle biopsy in nodular thyroid disease.
    (2017-03-01) Aysan, E; KIRAN, TUĞÇE; IDIZ, UO; AKBULUT, H; GULER, B; KUNDUZ, ENVER; ARICI, S; KADAKAL, G; Ozgor, M; Coci, K; AYŞAN, MUSTAFA ERHAN; KIRAN, TUĞÇE; GÜLER, BERIL; KUNDUZ, ENVER
    INTRODUCTION Non-diagnostic results of fine needle aspiration biopsy (FNAB) remain an important limitation of this technqiue. The aim of our study was to evaluate the results of core needle biopsy (CNB) of thyroid nodules and its effectiveness in non-diagnostic FNAB cases. METHODS CNBs were performed in 1,000 patients (154 male, 846 female; mean age: 50.2 years, range: 18–86 years) with a spring loaded 20G needle. Of these, 143 had initially had FNABs that were insufficient for evaluation. The CNB reports were reviewed. Patients with suspicious or malignant CNB results underwent total thyroidectomy. RESULTS When considering all 1,000 CNBs, the non-diagnostic rate was 1.5% (15/1,000). However, when the first 100 cases were eliminated as a learning curve, this reduced to 0.9% (8/900). Of the 143 cases with initial FNABs that were non-diagnostic, 0.7% (1/143) were also non-diagnostic on CNB. Twelve patients underwent surgery because of malignant CNB reports and all of these cases were confirmed as malignant by the postoperative pathology specimen results (100% accuracy). There were no major complications although three self-limiting minor complications were observed. CONCLUSIONS CNB is a safe and accurate method. It is more diagnostic than FNAB for nodular thyroid disease.
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    Effects of hyaluronic acid (Hyalonect) on callus formation in rabbits
    (2015-01-01T00:00:00Z) Ayanoglu, Semih; Esenyel, Cem Zeki; Adanir, Oktay; Dedeoglu, Semih; Imren, Yunus; Esen, Tuğçe; KIRAN, TUĞÇE
    Objective: Bone fragment and graft stabilization are important during reconstructive surgery of cases with comminuted fractures and bone defects. We examined the effect of Hyalonect surgical mesh on the healing dynamics of metaphyseal bone defects created in rabbit tibiae.