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Now showing 1 - 10 of 38
  • PublicationOpen Access
    Diagnostic value of dynamic contrast-enhanced magnetic resonance imaging in the evaluation of the biliary obstruction
    Purpose: In this study, our purpose was to investigate the diagnostic efficacy of the dynamic contrast-enhanced magnetic resonance imaging (MRI) method in the patients with bile duct obstruction. Materials and methods: 108 consecutive patients (53 men, 55 women, mean age; 55.77 ± 14.62, range 18-86 years) were included in this study. All the patients underwent conventional upper abdomen MRI using intravenous contrast material (Gd-DTPA) and MRCP in 1.5 Tesla MRI scanner. MRCP images were evaluated together with the T1 and T2w images, and both biliary ducts and surrounding tissues were examined for possible pathologies that may cause obstruction. Results: MRI/MRCP findings compared with final diagnoses, MRI/MRCP in the demonstration of bile duct obstruction sensitivity 96%, the specificity 100%, and accuracy 96.3%, in the detection of presence and level of obstruction, the sensitivity 96.7%, specificity 100%, and accuracy 97.2%, in the diagnosis of choledocholithiasis, the sensitivity 82.3%, specificity 96%, and accuracy 91.7%, and in the determination of the character of the stenosis, sensitivity 95.6%, specificity 91.3%, and accuracy 94.5% were found. Conclusion: The combination of dynamic contrast-enhanced MRI and MRCP techniques in patients with suspected biliary obstruction gives the detailed information about the presence of obstruction, location, and causes and is a highly specific and sensitive method.
  • PublicationOpen Access
    Severe Valvular Regurgitation: An Unexpected Complication During Transapical Aortic Valve Implantation Treated Successfully with the -Valve-in-Valve- Procedure
    (2012-12-01T00:00:00Z) BURGAZLI, Kamil Mehmet; KAVUKCU, Ethem; CHASAN, Ridvan; Bilgin, MEHMET; ERDOGAN, Ali; BİLGİN, MEHMET
    Severe symptomatic aortic stenosis (AS) in a multimorbid 77 year old female was treated with transapical aortic valve implantation with a 23 mm Edwards Sapien valve. Severe valvular regurgitation following implantation, probably due to structural valve failure, was treated successfully with a second valve-in-valve implantation. During a follow-up time of 2,5 years no further problems occurred.
  • PublicationMetadata only
    Platelet Glycoprotein IIb/IIIa Receptor Controls the Pro-Angiogenic Effect of Platelet Releasate
    (2011-11-22T00:00:00Z) ARSHAD, Muhammad; STAEDELE, Michael; ASLAM, Muhammad; HUSSAIN, Imran; RIAZ, Muhammad A.; SEDDING, Daniel G.; Bilgin, MEHMET; PIPER, Hans M.; NOLL, Thomas; GUENDUEZ, Dursun; BİLGİN, MEHMET
  • PublicationMetadata only
    post enfeksiyöz bronşiolitis obliterans hastalarının klinik ve radyolojik olarak değerlendirilmesi
    (2019-04-11T00:00:00Z) ABDİLLAHİ, FATOUMA KHALİF; Al Shadfan, Lina; Bilgin, Mehmet; Yazan, Hakan; Nursoy, Mustafa Atilla; ÇAKIR, ERKAN; BİLGİN, MEHMET; YAZAN, HAKAN; NURSOY, MUSTAFA ATİLLA
  • PublicationOpen Access
    Diffusion Tensor Imaging Can Discriminate the Primary Cell Type of Intracranial Metastases for Patients with Lung Cancer.
    (2021-03-04T00:00:00Z) Bilgin, Sabriye Sennur; Gultekin, Mehmet Ali; Yurtsever, Ismail; Yilmaz, Temel Fatih; Cesme, Dilek Hacer; Bilgin, Melike; Topcu, Atakan; Besiroglu, Mehmet; Turk, Haci Mehmet; Alkan, ALPAY; Bilgin, Mehmet; GÜLTEKİN, MEHMET ALİ; YURTSEVER, İSMAİL; YILMAZ, TEMEL FATİH; ÇEŞME, DİLEK HACER; TÜRK, HACI MEHMET; ALKAN, ALPAY; BİLGİN, MEHMET
    Purpose: Histopathological differentiation of primary lung cancer is clinically important. We aimed to investigate whether diffusion tensor imaging (DTI) parameters of metastatic brain lesions could predict the histopathological types of the primary lung cancer. Methods: In total, 53 patients with 98 solid metastatic brain lesions of lung cancer were included. Lung tumors were subgrouped as non-small cell carcinoma (NSCLC) (n = 34) and small cell carcinoma (SCLC) (n = 19). Apparent diffusion coefficient (ADC) and Fractional anisotropy (FA) values were calculated from solid enhanced part of the brain metastases. The association between FA and ADC values and histopathological subtype of the primary tumor was investigated. Results: The mean ADC and FA values obtained from the solid part of the brain metastases of SCLC were significantly lower than the NSCLC metastases (P < 0.001 and P = 0.003, respectively). ROC curve analysis showed diagnostic performance for mean ADC values (AUC=0.889, P = < 0.001) and FA values (AUC = 0.677, P = 0.002). Cut-off value of > 0.909 × 10-3 mm2/s for mean ADC (Sensitivity = 80.3, Specificity = 83.8, PPV = 89.1, NPV = 72.1) and > 0.139 for FA values (Sensitivity = 80.3, Specificity = 54.1, PPV = 74.2, NPV= 62.5) revealed in differentiating NSCLC from NSCLC. Conclusion: DTI parameters of brain metastasis can discriminate SCLC and NSCLC. ADC and FA values of metastatic brain lesions due to the lung cancer may be an important tool to differentiate histopathological subgroups. DTI may guide clinicians for the management of intracranial metastatic lesions of lung cancer.
  • PublicationMetadata only
    MRI of Pancreas in Patients with Chronic Pancreatitis and Healthy Volunteers: Can Pancreatic Signal Intensity and Contrast Enhancement Patterns be Valuable Predictors of Early Chronic Pancreatitis?
    (2017-01-01) Bilgin, Sabriye Sennur; Bilgin, MEHMET; Toprak, HÜSEYİN; BURGAZLI, K. Mehmet; CHASAN, Ritvan; ERDOGAN, Ali; Balci, Numan Cem; BİLGİN, MEHMET; TOPRAK, HÜSEYİN
    Background: Chronic pancreatitis is a progressive inflammatory disease of the pancreatic parenchyma and ductal structures. Typical MR imaging features of chronic pancreatitis include dilatation of the main pancreatic duct and irregularities of branch pancreatic ducts that can be evaluated with MRCP, loss of the normal high signal intensity of the pancreatic parenchyma on T1-weighted images, and decreased enhancement on dynamic contrast-enhanced sequences.
  • PublicationMetadata only
    Nontuberculous pulmonary cavitary diseases of childhood.
    (2015-03-01T00:00:00Z) Cakir, Erkan; Gedik, AH; Ari, E; Ozdemir, A; Cakir, FATMA BETÜL; Bilgin, M; Ziyade, S; ÇAKIR, ERKAN; ÇAKIR, FATMA BETÜL; UZUNER, SELÇUK; BİLGİN, MEHMET
  • PublicationOpen Access
    Comparison of tomographic and colonoscopic diagnoses in the presence of colonic wall thickening
    (2014-01-01) Ince, ALİ TÜZÜN; BAYSAL, Birol; KAYAR, Yusuf; Arabaci, ELİF; Bilgin, MEHMET; HAMDARD, Jamshid; YAY, Adnan; Senturk, HAKAN; İNCE, ALİ TÜZÜN; ARABACI, ELİF; BİLGİN, MEHMET; ŞENTÜRK, HAKAN
    Introduction and objective: Colonic wall thickening is a common condition in a number of benignant and malignant diseases. This study investigated the accuracy of radiological diagnoses in patients diagnosed with colonic wall thickening using multislice CT (MDCT). Materials and method: Files of patients with colonic wall thickening diagnosed with 64-slice MDCT were reviewed retrospectively. The colonoscopy results of these patients were grouped under neoplastic process (cancer and adenomatous polyp), inflammatory bowel disease (IBD), diverticulitis and other etiology (nonspecific events, ischemic colitis, solitary rectal ulcer, external compression, secondary to volvulus and radiotherapy), and the results were statistically evaluated. p values < 0.05 were considered statistically significant. Results: The study was performed on 505 files (290 males [57.4%], 215 females [42.6%], mean age: 49.15 ± 18.4 years). CT and colonoscopic diagnoses were reviewed and the following CT to colonoscopy ratios was observed: neoplastic process: 44.4% vs. 40.2%; IBD: 42.4% vs. 42.4%; diverticulitis: 4% vs. 4.2%; other etiology: 9.3% vs. 3.2%. Colonoscopy failed to identify pathology in 9.9% of the patients. The sensitivity, specificity, PPV, NPV and accuracy of CT were 95.6%, 90.4%, 87.1%, 96.8% and 92.4%, respectively, in detecting neoplastic processes; 97.2%, 97.9%, 97.2%, 97.9% and 97.6%, respectively, in detecting IBD; 90.5%, 99.8%, 95%, 99.6% and 99.4%, respectively, in detecting diverticulitis, and 50%, 96,7%, 62.5%, 94.6% and 92%, respectively, in detecting other etiology. Conclusion: While, accuracy of 64 slice-CT in diagnosing colonic wall thickenings secondary especially to neoplastic processes, IBD and diverticulitis was significantly higher, but differential diagnosis is challenging in pathologies due to other etiologies.
  • PublicationMetadata only
    T2 Signal Intensity of the Trigeminal Nerve: A New Diagnostic Criteria for Trigeminal Neuralgia?
    (2018-01-01) Hatiboglu, Mustafa A.; KAYA, Ozlem K.; Alkan, ALPAY; Timocin, GİZEM; BADUR, Bahar A.; Bilgin, MEHMET; ALKAN, ALPAY; HATİBOĞLU, MUSTAFA AZİZ; TİMOÇİN, GİZEM; BİLGİN, MEHMET
    Objectives: The objectives of this study were to: 1) compare the size and T2 signal intensity of the trigeminal nerves on the symptomatic side and asymptomatic side of the patients with idiopathic trigeminal neuralgia and to correlate these morphological findings with each other in order to assess whether Magnetic Resonance Imaging (MRI) can provide evidence of microstructural changes in the affected trigeminal nerve that could be potential imaging markers for diagnosis and monitoring trigeminal neuralgia 2) correlate these data with the pain score of the patients in order to search a quantitative evaluation method of the pain in patients with Trigeminal Neuralgia (TN).
  • PublicationMetadata only
    Diagnosis and treatment of deep-vein thrombosis and approach to venous thromboembolism in obstetrics and gynecology.