Person: DURDU, BÜLENT
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Publication Open Access Analysis of infectious spondylodiscitis: 7-years data(2018-11-01) Koc, Meliha Meric; Okay, GÜLAY; Akkoyunlu, YASEMİN; Bolukcu, SİBEL; Durdu, BÜLENT; Hakyemez, Ismail Necati; OKAY, GÜLAY; AKKOYUNLU, YASEMİN; BOLUKÇU, SİBEL; DURDU, BÜLENT; HAKYEMEZ, İSMAİL NECATİ; MERİÇ KOÇ, MELİHAObjective: Infectious spondylodiscitis (SD) is an infectious disease that is rare and difficult to diagnose due to its non-specific clinical features. In this study, we aimed to describe the clinical and diagnostic features of infectious spondylodiscitis. Methods: All patients who were diagnosed with SD at our hospital during a 7-year period from January 1, 2011 through December 31, 2017 were included in the study. Spondylodiscitis is divided into the following three types: pyogenic, tuberculous, and brucellar. Clinical and laboratory data were collected retrospectively from the medical records of the patients. Results: Of the 118 patients, 66 (55.9%) were female, 81 (68.6%) had pyogenic SD (PSD), 21 (17.8%) had tuberculous SD (TSD), and 16 (13.6%) had brucellar SD (BSD). The mean age was 59.3 ± 14.6 years. Leucocytosis was significantly higher in patients with PSD (p=0.01) than in patients with other types of SD. Thoracic involvement (47.6%) was significantly higher in patients with TSD (p=0.005) than in other patients. Sacral involvement (12.5%) was significantly higher in patients with BSD (p=0.01) than in other patients. Paravertebral abscess formation (42.8%) occurred most frequently in patients with TSD. Microbiologic agents were defined in 50% (18/36) of the surgical specimens and in 12.5% of the fine needle aspiration biopsy (FNAB) specimens. Staphylococcus aureus was the most common microbiological agent in patients with PSD. Spinal surgery was defined as a risk factor for PSD (p = 0.0001). Binary logistic regression analysis revealed that female gender, thoracic involvement and night sweats were the predictive markers for TSD (OR 4.5 [95% CI 1.3-15.3] and OR 5 [95% CI 1.7-14.6]). Conclusion: PSD is the most frequent form of SD. Leucocytosis is most common in patients with PSD. Thoracic involvement and paraspinal abscess were prominent in patients with TSD. Sacral involvement was most common in patients with BSD. Thoracic involvement, female gender and night sweats were the predictive markers for TSD. The microbiological culture positivity rate was higher in surgical specimens compared to FNAB specimens. The need for surgical treatment was most common in patients with TSD.Publication Metadata only Red Cell Volume Distribution Width to Platelet Ratio is an Important Predictor of Liver Fibrosis and Cirrhosis in Chronic Hepatitis B(2016-08-01) Hakyemez, Ismail Necati; BOLUKÇU, SİBEL; Durdu, BÜLENT; ASLAN, Turan; HAKYEMEZ, İSMAİL NECATİ; BOLUKÇU, SİBEL; DURDU, BÜLENTObjective: In recent years, a lot of non-invasive tests have been examined for estimating the severity of liver fibrosis in patients with chronic hepatitis B (CHB). We aimed to evaluate the role of simple and valuable platelet-derived indices in estimating the stage of fibrosis and cirrhosis in patients with CHB.Publication Metadata only Bezmialem Vakıf üniversitesi Tıp Fakültesi Hastanesi’nde influenza tanısı alan hastaların özellikleri(2016-05-15T00:00:00Z) KASAR, NURAY; DURDU, BÜLENT; SÜMBÜL, BİLGE; BOLUKCU, SİBEL; OKAY, GÜLAY; HAKYEMEZ, İSMAİL NECATİ; ASLAN, TURAN; DURDU, BÜLENT; SÜMBÜL, BİLGEPublication Metadata only Infective endocarditis case due to streptococcus parasanguinis presented with spondylodiscitis(2016-01-01) Hakyemez, Ismail Necati; Durdu, BÜLENT; Okay, GÜLAY; GULTEPE, Bilge; Bolukcu, SİBEL; ASLAN, Turan; HAKYEMEZ, İSMAİL NECATİ; DURDU, BÜLENT; OKAY, GÜLAY; BOLUKÇU, SİBEL; SÜMBÜL, BİLGEStreptococcus parasanguinis is a natural member of oral flora. It is an opportunistic pathogen, and rarely cause systemic infections due to it-s low virulence. Subacute infective endocarditis may present with various clinical manifestations (eg., spondylodiscitis). A sixty-five years old male patient from Northern Iraq has referred to our emergency service with high fever, weight loss, back pain and inability to walk. The patient was a veterinarian. He was operated three years ago for colonic carcinoma and irradiated. In magnetic resonance imaging, spondylodiscitis was detected localized in lumbar 1-2 region. Transthorasic echocardiography demonstrated aortic valve vegetation. S. parasanguinis was identified in the blood cultures. In conclusion; all in all, it-s remarkable to isolate S. parasanguinis as a causal agent of infective endocarditis in a patient who is a veterinarian with history of colonic carcinoma presented with clinical manifestation of spondylodiscitis.Publication Metadata only Bir Üniversite Hastanesine Ayaktan Başvuran >=65 Yaşındaki Yüz Yetmiş Dört Hastanın Değerlendirmesi(2017-04-04T00:00:00Z) BOLUKÇU, SİBEL; OKAY, GÜLAY; SÜMBÜL, BİLGE; HAKYEMEZ, İSMAİL NECATİ; DURDU, BÜLENT; AKKOYUNLU, YASEMİN; ASLAN, TURAN; SÜMBÜL, BİLGE; DURDU, BÜLENT; AKKOYUNLU, YASEMİNPublication Metadata only Nadir bir protez eklem enfeksiyonu etkeni: Salmonella paratyphi b.(2017-03-12T00:00:00Z) OKAY, GÜLAY; DURDU, BÜLENT; HAKYEMEZ, İSMAİL NECATİ; BOLUKCU, SİBEL; SÜMBÜL, BİLGE; ASLAN, TURAN; OKAY, GÜLAY; DURDU, BÜLENT; SÜMBÜL, BİLGEPublication Metadata only Kronik hepatit B hastalarında ABO ve Rh kan grupları ile karaciğer fibrozis şiddeti ve siroz varlığı ile ilişkisinin irdelenmesi(2016-03-17) HAKYEMEZ, İSMAİL NECATİ; DURDU, BÜLENT; Bolukçu, Sibel; ASLAN, TURAN; DURDU, BÜLENTPublication Metadata only Evaluation of the Relationship Between ABO/Rh Blood Groups and Severity of Liver Fibrosis in Patients with Chronic Hepatitis B(2016-04-01) Hakyemez, Ismail Necati; Durdu, BÜLENT; BOLUKÇU, SİBEL; ASLAN, Turan; HAKYEMEZ, İSMAİL NECATİ; DURDU, BÜLENT; BOLUKÇU, SİBELObjective: Studies on the severity of fibrosis in chronic viral hepatitis are scarce and limited with only hepatitis C infection. The aim of this study was to determine the role of ABO-Rh blood groups in the severity of fibrosis and progression to cirrhosis in patients with chronic hepatitis B (CHB).Publication Metadata only SALMONELLA ENTERİDİS’E BAĞLI NADİR BİR AMPİYEM OLGUSU(2015-04-01) Kurt Çınar, Ayşe Ruhkar; Bolukçu, Sibel; SÜMBÜL, BİLGE; DURDU, BÜLENT; HAKYEMEZ, İSMAİL NECATİ; ASLAN, TURAN; SÜMBÜL, BİLGE; DURDU, BÜLENTPublication Metadata only Protez Eklem Enfeksiyonlarının Risk Faktörleri ve Etkenlerin Dağılımı Açısından İrdelenmesi: Bir Üniversite Hastanesi Verileri(2017-04-08) BOLUKÇU, SİBEL; Okay, GÜLAY; Durdu, BÜLENT; HAKYEMEZ, İSMAİL NECATİ; AKKOYUNLU, YASEMİN; ASLAN, TURAN; OKAY, GÜLAY; BOLUKÇU, SİBEL; DURDU, BÜLENT; HAKYEMEZ, İSMAİL NECATİ; AKKOYUNLU, YASEMİN