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GEVHER, FATİH

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FATİH
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GEVHER
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  • PublicationMetadata only
    The effect of post-treatment PSA change and multiparametric prostate MRI findings in the detection of prostate cancer in patients receiving antibiotics due to PSA elevation
    (2020-07-24T00:00:00Z) Kayalı, Yunus; Doğan, Bayram; İlktaç, Abdullah; Ersöz, Cevper; Akçay, Muzaffer; Gevher, Fatih; Akbulut, Habib; Balbay, Mevlana Derya; DOĞAN, BAYRAM; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; AKÇAY, MUZAFFER; GEVHER, FATİH; AKBULUT, HABİB
  • PublicationOpen Access
    Comparison of Scoring Systems in Predicting Success of Percutaneous Nephrolithotomy
    (2019-01-01T00:00:00Z) AKÇAY, MUZAFFER; Tosun, Muhammed; GEVHER, FATİH; KALKAN, Senad; ERSÖZ, CEVPER; Kayali, Yunus; Tepeler, Abdulkadir; AKÇAY, MUZAFFER; TOSUN, MUHAMMED; GEVHER, FATİH; KALKAN, SENAD; ERSÖZ, CEVPER; KAYALI, YUNUS
    Background: Scoring systems are useful to inform the patients about the success and complication rates of the operation prior the surgery. Aims: To determine the applicability of the popular scoring systems (Guy’s, stone size, tract length, obstruction, number of involved calices, and essence/stone density and Clinical Research Office of the Endourological Society) by means of examining preoperative data of patients treated with percutaneous nephrolithotomy. Study Design: Cross sectional study. Methods: We retrospectively reviewed files of the patients who had undergone percutaneous nephrolithotomy in our center between 2011 and 2015. Excluded from the study were patients aged <18 years, and those who were not assessed preoperatively with computed tomography. Preoperative computed tomography images of all patients were assessed by a single observer, and patients were graded based on three scoring system. Demographic data were analyzed along with perioperative data (operation, fluoroscopy, length of hospital stay, changes in hematocrit values, location, and number of access sites, stone-free and complication rates). Results: A total of 298 patients who had been treated with 300 procedures were enrolled into the study. Mean age, stone burden, number of stones, and density were 48.1±12.9 years, 663.5±442.8 mm2, 1.8±1.1 and 888.3±273 HU respectively. Scores of the cases based on Guy’s, stone size, tract length, obstruction, number of involved calices, and essence/stone density, and Clinical Research Office of the Endourological Society scoring system were calculated as 2, 7.6, and 222.1 points respectively. 81.6% of the patients were stonefree. Complications were detected in 30 (9.9%) patients. Based on receiver operating characteristic curve analysis a positive correlation was detected between success rate and scoring systems, i.e., Guy’s (p=<0.001, r=-0.309), stone size, tract length, obstruction, number of involved calices, and essence/stone density (p=<0.001, r=-0.295), and Clinical Research Office of the Endourological Society (p=<0.001, r=0.426). The Clinical Research Office of the Endourological Society scoring system had the highest predictive value. The sensitivity rates rates for Guy’s, Clinical Research Office of the Endourological Society and Stone scoring system were as 78.78%, 80% and 82.34% respectively. Conclusion: All of scoring systems predicted correctly the success of the percutaneous nephrolithotomy procedures. The Clinical Research Office of the Endourological Society scoring system had the highest predictive value. Keywords: Percutaneous nephrolitotomy, scoring methods, specificity and sensitivity, urinary calculi
  • PublicationMetadata only
    Oxidative stress and phenotype frequencies of paraoxonase-1 in teratozoospermia.
    (2019-04-22) AKBULUT, H; Ozer, OF; GULER, ERAY METİN; CAGLAR, HİFA GÜLRU; GEVHER, FATİH; KOKTASOGLU, FATMANUR; SELEK, S; ÖZER, ÖMER FARUK; AKBULUT, HABİB; GÜLER, ERAY METİN; ÇAĞLAR, HİFA GÜLRU; GEVHER, FATİH; KÖKTAŞOĞLU, FATMANUR; SELEK, ŞAHABETTİN
    Oxidative stress causes infertility in men by affecting especially sperm morphology. The aim of the study was to examine the frequencies of paraoxonase-1 (PON1) phenotypes and the serum PON1, arylesterase, total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index, catalase and thiol levels in teratozoospermic infertile men and normospermic fertile men. The study included 184 teratozoospermic infertile men and 72 normospermic fertile men. The double substrate method was employed to determine the phenotype distribution of PON1. The evaluation of sperm morphology was made in accordance with the Kruger-s criteria. TAS, catalase and thiol levels were determined to be significantly lower in teratozoospermic infertile men compared to normospermic fertile men. A significant change was not observed in the levels of TOS, PON1 and arylesterase. There was a positive correlation between catalase and thiol levels and sperm morphology. While there were significantly more teratozoospermic men with AA phenotypes compared to normospermic men, there were significantly more persons with AB and BB phenotypes in normospermic men than in teratozoospermic men. As far as we know, such a study was conducted for the first time and suggests that PON1 phenotypic distribution may play a significant role in sterile males because of impaired sperm morphology.
  • PublicationMetadata only
    Outcomes of Hypospadias Surgery Performed by Different Surgeons Under the Supervision of an Experienced Pediatric Urology Surgeon
    (2019-06-01T00:00:00Z) Ozman, Oktay; Kuru, Murat; Gezer, Murat; GEVHER, FATİH; ÖNAL, Bülent; GEVHER, FATİH
    Objective: Hypospadias is one of the most common congenital anomalies among males. Hypospadias repair is still a challenging issue due to its results and frequently seen complications. The most commonly used techniques are the meatal advancement with glansplasty incorporated and tubularized incised plate urethroplasty. The experience of the surgeon is an important factor that influence the success of the surgery. In the literature, there are not enough data about the success of these operations done by different surgeons under the supervision of a pediatric urologist.
  • PublicationMetadata only
    Analysis of extended pelvic lymphadenectomy at robotic radical prostataectomy: Efficiency and correlation with patient and tumor characteristics.
    (2020-07-24T00:00:00Z) Gevher, Fatih; Doğan, Bayram; Kiremit, Murat Can; Sağlıcan, Yeşim; Balbay, Mevlana Derya; GEVHER, FATİH; DOĞAN, BAYRAM