Person: KÜTÜK, NÜKHET
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Publication Metadata only Horizontal Alveolar Distraction of the Mandibular Canine Regions for Implant Placement(2010-05-01T00:00:00Z) Bulut, Emel; Muglali, Mehtap; Celebi, Nükhet; Bekcioglu, Burak; KÜTÜK, NÜKHETHorizontal alveolar augmentation by distraction osteogenesis is an alternative method for reconstructing atrophic alveolar bone. A 65-year-old woman with atrophy of the alveolar rim in the anterior lower jaw, which had inadequate width for implant placement, was presented. Under general anesthesia, vertical and horizontal osteotomies of the buccolabial cortical bone were performed in the canine regions bilaterally. Modified horizontal distraction devices were stabilized to the mandible. Distraction proceeded from the seventh postoperative day at a rate of 0.450 mm twice a day for 6 days. After 3 months, distraction osteogenesis occurred and increased the alveolar width from 2 to 7 mm. Two implants were placed in the distracted areas. Marginal bone resorbtion around the implants was not observed 12 months after implant placement.Publication Metadata only Segmental Distraksiyon ile Alveol Yarık Onarımı: 2 Olgu Sunumu(2023-02-23) VATANSEVER S.; Pergel T.; AKKOYUN E. F.; KÜTÜK N.; DOLANMAZ D.; KILIÇ B.; YARADANAKUL K.; AKKOYUN, EMİNE FULYA; KÜTÜK, NÜKHET; DOLANMAZ, DOĞAN; KILIÇ, BANUPublication Metadata only Effects of combination TGF-B1 transfection and platelet rich plasma (PRP) on three-dimension chondrogenic differentiation of rabbit dental pulp-derived mesenchymal stem cells(2019-10-13) Salkin, Hasan; GÖNEN, ZEYNEP BURÇİN; ÖZCAN, SERVET; Lekesizcan, Ayca; BAHAR, DİLEK; KÜTÜK, NÜKHET; ALKAN, ALPER; KÜTÜK, NÜKHET; ALKAN, ALPERAim: The aim of this study was to evaluate the effects of standard culture medium and chondrogenic differentiation medium with PRP on chondrogenic differentiation of rabbit dental pulp-derived mesenchymal stem cells (rabbit DPSCs) that are transfected with transforming growth factor-beta 1 (TGF-B1) gene, based on the hypothesis of TGF- B1 and PRP can be effective on the chondrogenesis of stem cells. Materials and Methods: Rabbit DPSCs were characterized by using flow cytometry, immunofluorescent staining, quantitative Real Time Polymerase Chain Reaction (qRT-PCR) and differentiation tests. For the characterization, CD29, CD44 and CD45 mesenchymal cell markers were used. Rabbit DPSCs were transfected with TGF-B1 gene using electroporation technique in group 1; with PRP 10% in group 2; with chondrogenic medium in group 3; with both chondrogenic medium and PRP in group 4. DPSCs were cultured in medium with 10% inactive PRP in group 5, chondrogenic medium in group 6, chondrogenic medium with PRP 10% in group 7. SOX9, MMP13 and Aggrecan gene expression levels were evaluated in 3, 6, 12. and 24. days by qRT-PCR. Results: The expression levels of SOX9, MMP13 and Aggrecan were higher in group 2, 3 and group 7 in 3th day however in 24th day group 7 and group 2 were found higher. The expression levels changed by time-dependent. The extracellular matrix of the cells in experimental groups were positively stained with safranin O and toluidine blue. Conclusion: The combination in culture medium of TGF-B1 gene transfection and 10% PRP accelerates the chondrogenic differentiation of DPSCs.Publication Metadata only Graft Necrosis Occurred After Iliac Crest Reconstruction After Mandibular Segmental Resection of AmeloblastomaBulut, Emel; Bekcioglu, Burak; Bas, Burcu; KÜTÜK, NÜKHETAmeloblastoma is an uncommon benign odontogenic neoplasm of the maxillofacial region constituting less than 1% of tumors of the oral cavity. Ameloblastomas have been categorized broadly into 3 biologic variants: cystic (unicystic), solid, and peripheral. Unicystic ameloblastoma is a rare and less aggressive variant of ameloblastoma. The aim of this report is to describe a case of cystic ameloblastoma treated with segmental resection and iliac graft reconstruction. The possible reasons of graft failure seen in our patient at the early stage of the healing were also discussed.Publication Metadata only Acute fetal distress following tooth extraction and abscess drainage in a pregnant patient with maxillofacial infection(2013-03-01T00:00:00Z) Celebi, Nükhet; Kutuk, M. S.; TAŞ, Mert; SOYLU, Emrah; Etoz, O. A.; Alkan, A.; KÜTÜK, NÜKHET; ALKAN, ALPEROral infections have been implicated in adverse pregnancy outcomes such as pre-eclampsia, premature delivery and growth retardation. A 28-year-old and 9 months pregnant otherwise healthy woman with a complaint of facial swelling and dental pain was referred to the Department of Oral and Maxillofacial Surgery. Oral examination revealed perimandibular and masticator space infection related to the left mandibular third molar tooth. Eight hours after surgical intervention, fetal distress developed. The patient was immediately taken into surgery and a male baby delivered by Caesarean section. The baby was then admitted to the intensive care unit. On the twelfth day of his admission, the baby was discharged in good health. Severe maxillofacial infection in pregnancy is a medically complicated situation which should be treated by an oral and maxillofacial surgeon in consultation with an obstetric and gynaecology service.Publication Metadata only Displacement of a Dental Implant and Cover Screws into Submandibular Space: A Case Report.(2017-05-23T00:00:00Z) AKKOYUN, EMİNE FULYA; DEMİRBAŞ, AHMET EMİN; TAŞDEMİR, ZEKERİYA; KÜTÜK, NÜKHET; ALKAN, ALPER; AKKOYUN, EMİNE FULYA; KÜTÜK, NÜKHET; ALKAN, ALPERPublication Metadata only OXFORD DİŞ HEKİMLİĞİ SÖZLÜĞÜ(2018-01-01T00:00:00Z) AĞRALI, ÖMER BİRKAN; AK, GÜLSÜM; ALKAN, ALPER; ALTAN, GÜLAY; ARİFOĞLU, YASİN; AYTUĞAR, EMRE; BALCIOĞLU, HÜSEYİN AVNİ; BALCIOĞLU, NİLÜFER; BÜYÜKERTAN, METE; SUNGURTEKİN EKÇİ, ELİF; ERDEM, TAMER LÜTFİ; ERDEMİR, UĞUR; EROL, FUNDA; ERTAŞ, ÜMİT; GÜRSOY, HARE; İLGÜY, DİLHAN; ÖZKAN KARACA, EBRU; ÖZDEMİR KARATAŞ, MELTEM; KARAPINAR KAZANDAĞ, MERİÇ; KESKİN, BAŞAK; KÖSE, TAHA EMRE; KÜTÜK, NÜKHET; MARŞAN, GÜLNAZ; ÖZDEMİR ÖZENEN, DİDEM; ORHAN, KAAN; ÖZCAN, İLKNUR; ERMİŞ, RABİA BANU; SÜBAY, RÜSTEM KEMAL; ŞENER, YAĞMUR; ORDULU SÜBAY, MELİKE; TATLI, UFUK; TEKİN, UĞUR; ÖZÇAKIR TOMRUK, CEYDA; TUNA, SÜLEYMAN HAKAN; TUNÇDEMİR, ALİ RIZA; TÜRKÜN, LEZİZE ŞEBNEM; UYANIKGİL, YİĞİT; YAZICI, AYŞE RÜYA; YILDIZ, ESRA; YILMAZ, NERGİZ; KÜTÜK, NÜKHETPublication Metadata only Dudak Damak Yarığı Onarılmış Bir Hastada Ortognatik ve Kemik İçi İmplant Cerrahisi ile Dentofasiyal Deformitenin Tedavisi Olgu Sunumu(2017-09-24T00:00:00Z) BİLGE, SUHEYB; DEMİRBAŞ, AHMET EMİN; KÜTÜK, NÜKHET; ALKAN, ALPER; GÜL AMUK, NİSA; KILIÇ, KEREM; KÜTÜK, NÜKHET; ALKAN, ALPERPublication Metadata only Vertical ridge augmentation using guided bone regeneration procedure and dental pulp derived mesenchymal stem cells with simultaneous dental implant placement: A histologic study in a sheep model(2019-06-01) Colpak, H. A.; GÖNEN, ZEYNEP BURÇİN; Ozdamar, S.; ALKAN, ALPER; KÜTÜK, NÜKHET; ALKAN, ALPER; KÜTÜK, NÜKHETObjectives: To determine the effects of bone graft and dental pulp derived mesenchymal stem cells (DPMSCs) implantation with simultaneous dental implant placement on osteointegration, newly formed bone and vertical bone height histologically and histomorphometrically in a sheep model.Publication Metadata only Recurrent Unicystic Ameloblastoma of the Mandible: Case Report(2018-05-13T00:00:00Z) DEMİRBAŞ, AHMET EMİN; GULİYEV, ELVİN; BİLGE, SUHEYB; KÜTÜK, NÜKHET; KÜTÜK, NÜKHET