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ÇEŞME, DİLEK HACER

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DİLEK HACER

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ÇEŞME

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2015 - 201912020 - 202421
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    Diagnostic performance of apparent diffusion coefficient values for the differentiation of intrahepatic cholangiocarcinoma from gastrointestinal adenocarcinoma liver metastases
    (2021-12-22T00:00:00Z) Yilmaz, TEMEL FATİH; Gultekin, Mehmet Ali; Turk, Hacı Mehmet; Cesme, Dilek Hacer; Besiroglu, Mehmet; Simsek, Melih; Toprak, Huseyin; Alkan, ALPAY; YILMAZ, TEMEL FATİH; TÜRK, HACI MEHMET; ÇEŞME, DİLEK HACER; ŞİMŞEK, MELİH; ALKAN, ALPAY; TOPRAK, HÜSEYİN
    Background: We aimed to investigate whether there is a difference between intrahepatic cholangiocarcinoma (IHCC) and liver metastases of gastrointestinal system (GIS) adenocarcinoma in terms of apparent diffusion coefficient (ADC) values. Patients and methods: From January 2018 to January 2020, we retrospectively examined 64 consecutive patients with liver metastases due to gastrointestinal system adenocarcinomas and 13 consecutive IHCC in our hospital's medical records. After exclusions, fifty-three patients with 53 liver metastases and 10 IHCC were included in our study. We divided the patients into two groups as IHCC and liver metastases of GIS adenocarcinoma. For mean apparent diffusion coefficient (ADCmean) values, the region of interests (ROI) was placed in solid portions of the lesions. ADCmean values of groups were compared. Results: The mean age of IHCC group was 62.50 ± 13.49 and mean age of metastases group was 61.15 ± 9.18. ADCmean values were significantly higher in the IHCC group compared to the metastatic group (p < 0.001). ROC curves method showed high diagnostic accuracy (AUC = 0.879) with cut-off value of < 1178 x 10-6 mm2/s for ADCmean (Sensitivity = 90.57, Specificity = 70.0, positive predictive value [PPV] = 94.1, negative predictive value [NPV] = 58.3) in differentiating adenocarcinoma metastases from IHCC. Conclusions: The present study results suggest that ADC values have a potential role for differentiation between IHCC and GIS adenocarcinoma liver metastases which may be valuable for patient management.
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    Diffusion Tensor Imaging Can Discriminate the Primary Cell Type of Intracranial Metastases for Patients with Lung Cancer.
    (2021-03-04T00:00:00Z) Bilgin, Sabriye Sennur; Gultekin, Mehmet Ali; Yurtsever, Ismail; Yilmaz, Temel Fatih; Cesme, Dilek Hacer; Bilgin, Melike; Topcu, Atakan; Besiroglu, Mehmet; Turk, Haci Mehmet; Alkan, ALPAY; Bilgin, Mehmet; GÜLTEKİN, MEHMET ALİ; YURTSEVER, İSMAİL; YILMAZ, TEMEL FATİH; ÇEŞME, DİLEK HACER; TÜRK, HACI MEHMET; ALKAN, ALPAY; BİLGİN, MEHMET
    Purpose: Histopathological differentiation of primary lung cancer is clinically important. We aimed to investigate whether diffusion tensor imaging (DTI) parameters of metastatic brain lesions could predict the histopathological types of the primary lung cancer. Methods: In total, 53 patients with 98 solid metastatic brain lesions of lung cancer were included. Lung tumors were subgrouped as non-small cell carcinoma (NSCLC) (n = 34) and small cell carcinoma (SCLC) (n = 19). Apparent diffusion coefficient (ADC) and Fractional anisotropy (FA) values were calculated from solid enhanced part of the brain metastases. The association between FA and ADC values and histopathological subtype of the primary tumor was investigated. Results: The mean ADC and FA values obtained from the solid part of the brain metastases of SCLC were significantly lower than the NSCLC metastases (P < 0.001 and P = 0.003, respectively). ROC curve analysis showed diagnostic performance for mean ADC values (AUC=0.889, P = < 0.001) and FA values (AUC = 0.677, P = 0.002). Cut-off value of > 0.909 × 10-3 mm2/s for mean ADC (Sensitivity = 80.3, Specificity = 83.8, PPV = 89.1, NPV = 72.1) and > 0.139 for FA values (Sensitivity = 80.3, Specificity = 54.1, PPV = 74.2, NPV= 62.5) revealed in differentiating NSCLC from NSCLC. Conclusion: DTI parameters of brain metastasis can discriminate SCLC and NSCLC. ADC and FA values of metastatic brain lesions due to the lung cancer may be an important tool to differentiate histopathological subgroups. DTI may guide clinicians for the management of intracranial metastatic lesions of lung cancer.
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    Evaluation of Optical Radiation from Visual Pathways with Diffusion Tensor Imaging in Patients with Neurofibromatosis Type 1
    (2021-10-01T00:00:00Z) ÇEŞME, DİLEK HACER; ÇEŞME, DİLEK HACER
    Objective: It was investigated whether patients with neurofibromatosis type 1 (NF1) with and without optic glioma (OG) differed from the healthy control group in terms of diffusion tensor imaging (DTI) parameters obtained from optic radiation. Methods: Eighty three patients and 36 healthy controls followed with the diagnosis of NF1 were included in the study. Routine MRI and DTI were applied to all subjects. Fractional anisotropy (FA), mean diffusity (MD), radial diffusity (RD) and axial diffusity (AD) values were calculated by placing ROI on the right and left optic radiation on colored FA maps. Patients with OG detected by conventional magnetic resonance imaging (n=19) were classified as group 1, patients with NF1 without OG (n=64) were classified as group 2 and they were compared with the healthy control group in terms of DTI parameters. Results: The right and left optic radiation FA values of the patients in group 1 and group 2 were significantly different when compared with the healthy control group. Optical radiation FA values were significantly lower than healthy control group. MD values in group 1 patients with OG were significantly higher than healthy control group. Optic radiation RD values were significantly higher in group 1 and group 2 compared with healthy control group. Conclusion: There appears to be microstructural damage in optic radiation in patients with NF1 with or without OG. The idea that changes in FA values detected in optic radiation in visual pathways in patients with NF1 can be predicted in the early period of visual impairment is promising in terms of treatment planning and management.
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    Antero-posterior axis of the tibia is a better landmark for tibial component rotation in Oxford medial unicompartmental knee arthroplasty.
    (2022-09-20T00:00:00Z) Aliyev, O; Ağır, M; Aghazada, A; Çeşme, DH; Kara, D; Toprak, ALİ; Tuncay, İ; Yıldız, F; ÇEŞME, DİLEK HACER; TOPRAK, ALİ
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    A Case of Neurosarcoidosis Mimicking Brain Tumor
    (2021-01-01T00:00:00Z) SARI, LÜTFULLAH; PEKER, ABDUSSELİM ADİL; ÇEŞME, DİLEK HACER; ALKAN, ALPAY; SARI, LÜTFULLAH; PEKER, ABDUSSELİM ADİL; ÇEŞME, DİLEK HACER; ALKAN, ALPAY
    Background: Neurosarcoidosis manifests symptomatically in 5% of patients with sarcoidosis and diagnosis can be challenging if not clinically suspected. Cerebral mass-like presentation of neurosarcoidosis rarely reported in the literature. We presented a woman with neurosarcoidosis who had a cerebral mass-like lesion which completely disappeared after medical treatment.
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    Is quantitative diffusion-weighted MRI a valuable technique for the detection of changes in kidneys after extracorporeal shock wave lithotripsy?
    (2015-01-01T00:00:00Z) Hocaoglu, Elif; Inci, Ercan; Aydin, Sibel; Cesme, DİLEK HACER; Kalfazade, Nadir; ÇEŞME, DİLEK HACER
    Objective: The aim of this study was to evaluate the capability and the reliability of diffusion-weighted imaging (DWI) in the changes of kidneys occurring after extracorporeal shock wave lithotripsy (ESWL) treatment for renal stones.
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    Importance of thalamo-striatal pathway associated with neurocognitive dysfunctions in children with Neurofibromatosis type 1; Diffusion Tensor Imaging Findings
    (2021-03-01T00:00:00Z) Aydın, Sinem; İşcan, Akın; Çeşme, Dilek Hacer; Alkan, Alpay; Gultekin, Mehmet Ali; Peker, Abdusselim; ÇEŞME, DİLEK HACER; ALKAN, ALPAY
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    Presence of Auditory Pathway Abnormalities in Children With Neurofibromatosis Type 1 With Brainstem Focal Areas of Abnormal Signal Intensity: Diffusion Tensor Imaging Features
    (2024-06-10) Cesme D. H.; Atasoy B.; Alkan G.; Peker A. A.; Yilmaz T. F.; Yurtsever I.; Iscan A.; Alkan A.; ÇEŞME, DİLEK HACER; ATASOY, BAHAR; PEKER, ABDUSSELİM ADİL; YILMAZ, TEMEL FATİH; YURTSEVER, İSMAİL; İŞCAN, AKIN; ALKAN, ALPAY
    Background: To investigate whether there is a difference in mean diffusivity (MD) and fractional anisotropy (FA) values in the auditory pathways of neurofibromatosis type 1 patients with and without focal areas of abnormal signal intensity (FASI) compared to healthy controls by using diffusion tensor imaging (DTI). Methods: Patients were classified as group 1 with focal areas of abnormal signal intensity in the brainstem, group 2 without focal areas of abnormal signal intensity, and healthy control group 3 according to the MRI findings. Mean diffusivity and fractional anisotropy values of lateral lemniscus, inferior colliculus, corpus geniculatum mediale, Heschl gyrus, and brainstem were compared between groups. The correlation between mean diffusivity and fractional anisotropy values of auditory pathways and age was investigated. Results: There was a significant difference between group 1 and group 2 in terms of mean diffusivity and fractional anisotropy values at lateral lemniscus, inferior colliculus, corpus geniculatum mediale, and Heschl gyrus. Increased mean diffusivity and decreased fractional anisotropy values at brainstem were found in group 1. There was a significant difference between group 1 and group 3 in terms of mean diffusivity values at all auditory pathways. Fractional anisotropy values obtained from lateral lemniscus, inferior colliculus, and Heschl gyrus decreased in group 1 compared with group 3. There was a negative correlation between mean diffusivity values and positive correlation between fractional anisotropy values at lateral lemniscus, inferior colliculus, Heschl gyrus, and age. Conclusions: Our diffusion tensor imaging findings show that the neuronal integrity of the auditory pathways is affected in neurofibromatosis type 1 patients with brainstem focal areas of abnormal signal intensity. We think that the disappearance of brainstem focal areas of abnormal signal intensity associated with myelin repair and the regression of diffusion tensor imaging changes in the auditory pathways occur simultaneously with advancing age in patients with neurofibromatosis type 1.
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    Does previous arthroscopic Bankart repair influence coracoid graft osteolysis in Latarjet procedure? A case-control study with computed tomography scan data
    (2023-01-01) ŞAHİN K.; Sarıkaş M.; Çeşme D. H.; Topal M.; KAPICIOĞLU M.; Bilsel K.; ŞAHİN, KORAY; SARIKAŞ, MURAT; ÇEŞME, DİLEK HACER; KAPICIOĞLU, MEHMET; BİLSEL, İSMAIL KEREM
    Background: The Latarjet procedure is commonly performed in the treatment of recurrent shoulder instability and is also indicated as a salvage procedure for recurrence after failed arthroscopic Bankart repair. Although this procedure has shown success, there has been an increased awareness of complications in recent studies, especially graft osteolysis. Most relevant research has focused on the pathophysiology, incidence, or location of graft osteolysis or the risk factors for graft osteolysis; however, the data are limited to primary Latarjet procedures. This study aimed to investigate the effect of previous arthroscopic Bankart repair surgery on coracoid bone graft osteolysis in the Latarjet procedure. Methods: This retrospective case-control study analyzed data from patients who underwent primary Latarjet procedures or revision Latarjet procedures following failed arthroscopic Bankart repair. Clinical outcome measures included range of motion, the Subjective Shoulder Value, and the Rowe score. Volumetric analysis of each transferred coracoid graft was performed using early postoperative and late postoperative computed tomography scan data, and the amount of graft osteolysis was then calculated as the percentage of volume reduction of each graft. Results: A total of 32 patients who met the inclusion criteria were included in this study, with 24 patients in the primary Latarjet group (group I) and 8 patients in the revision Latarjet group (group II). The mean age of the patients was 32.5 ± 7.7 years, and the mean follow-up duration was 52.1 ± 8.9 months. Both study groups showed significant improvement in the Subjective Shoulder Value compared with baseline (P .05). No recurrence was observed during the follow-up period. A positive apprehension sign was present in 6 patients (25%) in group I and 4 patients (50%) in group II (P > .05). Analysis of radiologic data revealed that all patients underwent some degree of graft osteolysis, with varying osteolysis ratios between 12% and 98%. The mean osteolysis ratio of the coracoid graft was 67.3% ± 22.6% in group I and 69.4% ± 25.6% in group II, with no significant difference between the 2 groups (P > .05). Conclusion: The findings of this study suggest that a considerable amount of coracoid graft osteolysis is observed after both primary Latarjet procedures and revision Latarjet procedures following failed arthroscopic Bankart repair. Previous arthroscopic Bankart repair did not seem to have a significant influence on the amount of graft osteolysis, and both primary and revision Latarjet procedures showed satisfactory clinical outcomes.
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    Clinical and radiological evaluation of treated Chiari I adult patients: retrospective study from two neurosurgical centers
    (2020-10-01T00:00:00Z) Papaker, Meliha Gundag; Abdallah, Anas; ÇEŞME, DİLEK HACER; GÖNEN, GÜVEN; Asilturk, Murad; Avyasov, Rashid; Sofuoglu, Ozden Erhan; Abdallah, Betul Guler; Emel, Erhan; GUNDAG, MELİHA; ÇEŞME, DİLEK HACER; GÖNEN, GÜVEN
    Chiari malformation type I (CM1) is a common neurosurgical disorder. It often causes debilitation in the affected patients. CM1 is a herniation of the caudal cerebellum into the spinal canal. This study aimed to evaluate the clinical and radiological outcomes of posterior fossa decompression and duraplasty (PFDD) in treated CM1 patients. In retrospective design, we reviewed the medical records of diagnosed patients with CM1 at two neurosurgical centers spanning 8 years from 2010 to 2017. We selected all CM1 patients who underwent PFDD surgery (n = 72) as the core sample for this study. We used the Chicago Chiari Outcome Scale (CCOS) to evaluate clinical outcomes. Pre- and postoperatively, we assessed the syrinx/cord ratio, the syrinx length, and the improvement of aqueductal stroke volume (ASV) on CSF flow MRIs. The mean value of CCOS was 14.1 +/- 2.1. On midsagittal MRIs, the mean regression in ectopia tonsils was 9.4 +/- 1.9 mm (i.e., mean pre- and postoperative tonsil herniation was 13.1 +/- 3.1 mm and 4.0 +/- 1.6 mm, respectively;p < 0.001). On coronal MRIs, the mean regression in ectopia tonsils was 8.4 +/- 1.5 mm (i.e., mean pre- and postoperative tonsil herniation was 13.9 +/- 2.4 mm and 5.8 +/- 1.0 mm, respectively;p < 0.001). A strong positive correlation was observed between clinical improvement and the increase in ASV values. CSF flow MRIs can help in the surgical decision and follow-up of CM1 patients. ASV <= 12 mu l is a significant predictor for surgical intervention. Full clinical and radiological evaluation utilizing CSF flow MRI are essential. Most syrinx cavities have regressed following PFDD.