Person: KILIÇ, ÖZGE
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Publication Open Access COVID-19 infection, vaccine status, and avoidance behaviors in adults with attention deficit and hyperactivity disorder: A cross-sectional study(2022-08-01) KILIÇ Ö.; BOYLU M. E.; Karakaya-Erdur S.; Suma-Berberoglu M.; Gudjonsson G.; Young S.; Deveci E.; KIRPINAR İ.; KILIÇ, ÖZGE; BOYLU, MUHAMMED EMİN; DEVECİ, ERDEM; KIRPINAR, İSMETObjective: We aim to examine infection risk and vaccine status of COVID-19 in attention deficit and hyperactivity disorder and evaluate the impact of demographic, clinical, and COVID-19-related factors on the infection status and behavioral avoidance of COVID-19. Methods: This cross-sectional study assessed adults with attention deficit and hyperactivity disorder recruited from an outpatient psychiatry clinic. Patients and healthy controls completed a survey on sociodemographic data, COVID-19 infection status, and vaccine status. COVID-19 Disease Perception Scale, COVID-19 Avoidance Attitudes Scale, Attitudes toward COVID-19 Vaccine Scale, Adult Attention Deficit and Hyperactivity Disorder Self-report Screening Scale for DSM-5, Adult Attention Deficit and Hyperactivity Disorder Self-Report Scale Symptoms Checklist, Patient Health Questionnaire-9, and State-Trait Anxiety Inventory were applied. Results: Ninety patients and 40 healthy controls participated. Patients did not differ from controls in COVID-19 infection and vaccine status, and behavioral avoidance of COVID-19. No demographic and clinical factor significantly affected the COVID-19 infection status. Patients scored higher than controls in the perception of COVID-19 as contagious (p = 0.038), cognitive avoidance of COVID-19 (p = 0.008), and positive attitudes toward the COVID-19 vaccine (p = 0.024). After adjustment of possible factors, a positive perception of the COVID-19 vaccine and a perception of COVID-19 as dangerous were the two factors significantly affecting behavioral avoidance of COVID-19 [R 2 = 0. 17, F(2) = 13.189, p < 0.0001]. Conclusion: Infection and vaccine status of COVID-19 in patients did not significantly differ from controls. No demographic and clinical factor significantly affected the COVID-19 infection status. Approximately four-fifths of the patients were fully vaccinated as recommended by national and global health organizations. This has increased the knowledge base showing that the COVID-19 vaccine is acceptable and receiving the vaccine is endorsed by ADHD patients. Attention deficit and hyperactivity disorder itself may provoke no kind of mental disturbance in sense of perception of the danger of this disease. Our findings have increased the knowledge base showing that the COVID-19 vaccine is acceptable and the actual practice of receiving the vaccine is endorsed in this population. Our message for practice would be to take into account not only the core symptoms and the comorbidities of the disorder but also the perception of the disease while exploring its link with COVID-19.Publication Open Access Assessment of loneliness in patients with inflammatory arthritis(2020-12-01T00:00:00Z) Emmungil, Hakan; Ilgen, Ufuk; Turan, Sezin; KILIÇ, ÖZGE; KILIÇ, ÖZGEAim: This study aimed to explore loneliness and associated factors in Turkish patients with inflammatory arthritis. Method: Adult patients with rheumatoid arthritis (RA) (n = 58), ankylosing spondylitis (AS) (n = 53), and psoriatic arthritis (PsA) (n = 30), respectively, were included in the study. A single-item visual analog scale (VAS) for loneliness, UCLA Loneliness Scale-8 (ULS-8), Beck depression inventory (BDI), Beck anxiety inventory (BAI), revised multidimensional scale of perceived social support, Health Assessment Questionnaire-Disability Index (HAQ-DI) were used for the psychometric and functional assessments. Multiple regression models were generated for predicting the ULS-8 and HAQ-DI scores. Results: There was no difference between disease groups in terms of the ULS-8 and HAQ-DI scores. Among demographic and clinical parameters, only the education status and number of drugs used had associations with the ULS-8 score. Single-item VAS score for loneliness did not predict the ULS-8 score well. There were significant correlations between the ULS-8 and HAQ-DI, depression, anxiety, social support, and physician global VAS scores. Only the education status significantly predicted (β = -0.208) the ULS-8 score in multiple regression analysis (adjusted R2 = 0.15, P < .001). Beck depression, anxiety, and patient global VAS scores remained significant for predicting the HAQ-DI after multiple regression with the covariates ULS-8, depression, anxiety, social support, patient and physician global VAS scores, and the number of drugs used (adjusted R2 = 0.53, P < .001). Disease activity and the ULS-8 scores were not found to be associated in any disease group. Conclusion: Loneliness is associated with depression, anxiety, lack of social support, disability, higher number of drugs used, and lower education but not with disease activity in Turkish patients with RA, AS, and PsA. Perception and expression of loneliness vary according to the cultural background. Single-item scales for loneliness may lack reliability compared to the more comprehensive ULS-8. Keywords: ankylosing spondylitis; inflammatory arthritis; loneliness; psoriatic arthritis; rheumatoid arthritis; social support.Publication Open Access COVID-19 related mental health issues: a narrative review of psychometric properties of scales and methodological concerns in scale development(2021-01-01T00:00:00Z) Ransing, Ramdas; Dashi, Elona; Rehman, Sajjadur; Mehta, Varun; Chepure, Ashish; KILIÇ, ÖZGE; Hayatudeen, Nafisatu; Orsolini, Laura; Vahdani, Bita; Adiukwu, Frances; Gonzalez-Diaz, Jairo M; Larnaout, Amine; Pinto da Costa, Mariana; Grandinetti, Paolo; Soler-Vidal, Joan; Bytyçi, Drita Gashi; Shalbafan, Mohammadreza; Nofal, Marwa; Pereira-Sanchez, Victor; Ramalho, Rodrigo; KILIÇ, ÖZGE© The Royal Australian and New Zealand College of Psychiatrists 2021.Objectives: The global crisis of COVID-19 and its consequential strict public health measures placed around the world have impacted mental health. New scales and tools have been developed to measure these mental health effects. This narrative review assesses the psychometric properties of these scales and tools and methodological aspects of their development. Methods: PubMed, PubMed Central, and Google Scholar were searched for articles published from 15 May 2020 to 15 August 2020. This search used three groups of terms (-tool- OR -scale- AND -mental- OR -psychological-; AND -COVID-19- OR -coronavirus-). The identified scales were further evaluated for their psychometric properties and methodological aspects of their development. Results: Though the studies developing these scales (n = 12) have demonstrated their robust psychometric properties, some methodological concerns are noteworthy. Most of the scales were validated using internet-based surveys, and detailed descriptions of the mode of administration, sampling process, response rates, and augmentation strategies were missing. Conclusions: The heterogeneous and inadequate reporting of methods adopted to evaluate the psychometric properties of the identified scales can limit their utility in clinical and research settings. We suggest developing guidelines and checklists to improve the design and testing, and result in reporting of online-administered scales to assess the mental health effects of the COVID-19 pandemic.Publication Open Access Fear During COVID-19 pandemic: Fear of COVID-19 Scale Measurement Properties(2021-09-01T00:00:00Z) Ullah, Irfan; Jaguga, Florence.; Ransing, Ramdas; Pereira-Sanchez, Victor; Orsolini, Laura; Ori, Dorottya; de Filippis, Renato; Pakpour, Amir H.; Adiukwu, Frances; KILIÇ, ÖZGE; Hayatudeen, Nafisatu; Shoib, Sheikh; Ojeahere, Margaret Isioma; Nagendrappa, Sachin; Handuleh, Jibril I. M.; Dashi, Elona; Musami, Umar Baba; Vahdani, Bita; Ashrafi, Agaah; Jatchavala, Chonnakarn; Abbass, Zargham; El Halabi, Sarah; Ogunnubi, Oluseun Peter; Pinto da Costa, Mariana; Ramalho, Rodrigo; KILIÇ, ÖZGEPublication Open Access Evaluating compliance to stimulants in adults with attention deficit and hyperactivity disorder(2021-12-03T00:00:00Z) Kılıç, Özge; Boylu, Muhammed Emin; KILIÇ, ÖZGE; BOYLU, MUHAMMED EMİNObjective: Attention deficit hyperactivity disorder (ADHD) has several negative psychosocial outcomes including poor work performance, academic failure, problems in social relationships, and criminality. However, it is among the most treatable mental disorders given the safety and efficacy of stimulants. We aimed to explore compliance levels to methylphenidate and associated sociodemographic factors in adults with ADHD.Methods: Patients with ADHD who have been following up in a single-center outpatient psychiatry clinic of a university hospital were included in the study. Diagnoses were established according to the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) during a face-to-face clinical interview. Sociodemographic data form and Morisky medication adherence scale were utilized.Results: Among 64 patients (36 males, 28 females) (mean age ± SD = 25.2 ± 6.8) with ADHD, 19 (29.7 %) and 29 (45.3%) patients showed high and medium adherence to methylphenidate respectively. However, 16 (25 %) had low adherence. Men and women did not significantly differ in compliance levels to stimulants (X2 (2) = 1.639, p = 0.441). Compliance was not found to be related to education, marital and economic status, living conditions, smoking. The number of patients who consume alcohol tends to be higher in the low adherent group although not reaching statistical significance.Discussion: One-fourth of adult patients with ADHD had low adherence to methylphenidate. Men and women did not differ in adherence levels. No significant difference has been observed in the mean ages between the three adherence groups. Our results were in line with some earlier studies on treatment adherence in ADHD but not with others that showed adherence was higher in females and younger patients. The reason for these discrepancies could be that the studies with contrary results have recruited both children and adolescents. Longitudinal multicenter studies are needed to draw conclusions on the factors affecting compliance in ADHD.Keywords: attention deficit and hyperactivity disorder, drugs/medication, pharmacology, treatment compliance, treatment adherence, demographic